No abstract available.
Meningitis, Bacterial*

No abstract available.
Meningitis, Bacterial*

No abstract available.
Ethmoid Bone* ; Meningitis, Bacterial*

Population-based epidemiologic surveillance for bacterial meningitis in Hanoi from 2000 to 2002. The population under surveillance consists of children under 5 years of age, living in Hanoi urban districts. The results showed that bacterial meningitis represents an important cause of infant and childhood morbidity in Vietnam.
Meningitis, Bacterial ; epidemiology

No abstract available.
Meningitis, Bacterial* ; Stapes*

No abstract available.
Epidural Abscess* ; Meningitis, Bacterial*

BACKGROUND AND OBJECTIVE

Accurately diagnosing bacterial meningitis and ventriculitis in children is challenging due to nonspecific symptoms and the lack of specificity in conventional CSF parameters. Cerebrospinal fluid (CSF) procalcitonin (PCT) is a promising diagnostic marker but studies on its utility in children are lacking. We aimed to assess the diagnostic value of CSF procalcitonin for bacterial meningitis and ventriculitis in children and establish a clinically relevant cut-off level.

A total of 131 patients were included in the study, and the CSF PCT levels were measured in two groups. Group 1 comprised of patients with bacterial meningitis and ventriculitis (n=21), while Group 2 consisted of patients with tuberculous meningitis, fungal meningitis, viral encephalitis, autoimmune encephalitis, central nervous system (CNS) leukemia, and non-infectious or inflammatory CNS conditions (n=110).

CSF PCT demonstrated an area under the curve of 96.57% in the receiver operating characteristic analysis. With a cut-off of 0.19 ng/mL, it achieved high sensitivity (90.48%) and specificity (91.82%), making it an excellent test for distinguishing between bacterial meningitis and ventriculitis from control diseases.

CSF procalcitonin is highly effective in distinguishing pediatric bacterial meningitis and ventriculitis. Especially in clinical scenarios where the conventional laboratory tests are inconclusive, it can complement clinical assessment to diagnose CNS infections accurately and guide prudent antibiotic use.

To evaluate the diagnostic value of lactate dehydrogenase (LDH) in bacterial meningitis (BM) and viral meningitis (VM), LDH was determined simultaneously in cerebrospinal fluid (CSF) and in sera of 89 children suffering from meningitis (51 BM and 38 VM) by 3 time (acute phase, 7-10 days later, and recovering period). Control group consists of 33 normal children. In blood, LDH activity was always elevated, statistically different from control group (p<0.05) but these was no difference between BM and VM. So LDH in sera isn't helpful in the differential diagnosis between BM and VM. In contrast, LDH activity in CSF was highly statistical difference from control group (p<0.001) and there was statistical different between BM and VM. Therefore, LDH activity in CSE has great value in the differential diagnosis between BM and VM; it possesses prognostic value in BM.
Meningitis ; cerebrospinal fluid ; blood ; Meningitis, Bacterial ; Meningitis, Viral

No abstract available.
Eosinophilic Granuloma* ; Eosinophils* ; Meningitis, Bacterial*

No abstract available.
Humans ; Infant, Newborn ; Meningitis, Bacterial*