Objective To explore the effects of Xingnaojing injection on plasma MMP-9 and TIMP-1 levels for patients with cerebral hemorrhage. Methods A total of 60 patients with acute cerebral hemorrhage from February 2014 to May 2015 were selected as research subjects and randomly divided into the research group and the control group, with 30 patients in each group. The research group was given Xingnaojing injection on the basis of regular treatment, and the control group was given regular treatment. The plasma MMP-9 and TIMP-1 levels of the two groups of patients were compared, and the correlation between MMP-9 and TIMP-1 levels in the patients and their correlation with cere-bral edema were analyzed. Results On the fifth day of onset of the disease in the two groups of patients, MMP-9 and TIMP-1 levels were significantly increased, and the levels were reduced on the 14th day. On the fifth day and 14th day of onset of the disease in the research group, MMP-9 level was significantly lower than that in the control group, and TIMP-1 level was significantly higher than that in the control group. The differences were statistically significant (P<0.01). In 24 h, the volume of cerebral edema in the two groups was positively correlated to MMP-9 (r=0.682, P=0.761), and was significantly negatively correlated to TIMP-1(r=-0.489, P=-0.619); on the 14th day, the volume of cerebral edema was positively correlated to MMP-9 (r=0.516, P=0.835). Conclusion Xingnaojing is able to significantly reduce the increasing degree of MMP-1 in the patients with cerebral hemorrhage, enhance the increasing degree of TIMP-1, and improve patients' cerebral edema.

Objective:To explore the application effect of 5E rehabilitation management model in the rehabilitation of stroke patients with hemiplegia.Methods:A total of 98 stroke patients with hemiplegia who were admitted to the Second Affiliated Hospital of Zhengzhou University from May 2020 to April 2021 were selected by the convenient sampling method. According to the random number table method, they were divided into the control group ( n=49) and the experimental group ( n=49) . The control group adopted the conventional rehabilitation management mode of stroke hemiplegia, while the experimental group adopted the 5E rehabilitation management model. Motor function and quality of life were compared between the two groups. Results:After 3 months of intervention, the motor function scores and quality of life scores of the experimental group and the control group were higher than those before intervention, and the motor function scores and quality of life scores of the experimental group were higher than those of the control group, and the differences were statistically significant ( P<0.05) . Conclusions:The 5E rehabilitation management model can improve the outcome of limb function rehabilitation and improve the quality of life of stroke patients with hemiplegia.