Since 2007 the state and the Ningxia Hui Autonomous Regional Government gave strongly support to Hui medicine and medical hospital, Ningxia Hui medical hospital has attained great development. But some problems must be pay attention to, such as lacking of special person and the poor knowledge of Hui medical hospital. So how to promote the sustainable development of Hui medical hospital was becoming a vital problem. Based on the previous studies and researches, this paper summarized the following five aspects:strategic positioning, product development, medical services, policy environment, cultural propaganda of Hui medical hospital, trying to build a "Five in One" characteristic development pattern of Ningxia Hui medical hospital and laying a solid foundation for the development of Hui medicine and Hui medical hospitals.

BACKGROUNDTo investigate the methylation and deletion of p16 gene and its diagnostic value in non-small cell lung cancer.

METHODSA total of 50 lung cancer tissues and 54 normal lung tissues were examined for p16 gene methylation in exon 1 and deletion in exon 2 by PCR based methylation analysis and duplex PCR respectively.

RESULTSOut of 50 lung cancer tissues, 16 were positive for the p16 gene exon 1 methylation (32.0%), and 14 for the p16 gene exon 2 deletion (28.0%). However, in 54 cases of normal lung tissues, only 2 showed the p16 gene exon 1 methylation(3.7%), and none showed the p16 gene exon 2 deletion. There were significant differences in methylation rate (Fisher's exact= 0.000 ) and deletion rate (Fisher's exact= 0.000) between the two groups.

CONCLUSIONSThe methylation and deletion may be important mechanisms for p16 gene inactivation in non-small cell lung cancer. The detection of p16 gene status may contribute to the diagnosis of lung cancer.