Objective To explore the changes of residual lipoprotein-cholesterol (RLP-C) after three meals in coronary heart disease group and control group, to explore the best time point for detecting post-prandial RLP-C levels. Methods Thirty-one patients andcontrols were recruited and divided into coronary heart disease group and control group. Vein blood samples were collected at 4 hours of fasting and three meals, and serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) concentrations were measured. Serum RLP-C levels was calculated according to the equation. Results There were no significant differences in serum fasting TC, TG, LDL-C, non-HDL-C and RLP-C levels between CHD patients and controls (P＞ 0. 05). The CHD patients had lower HDL-C concentrations than controls (P ＜ 0. 05). Postprandial serum TG and RLP-C levels increased significantly in CHD patients after each meal (P ＜ 0. 01), and reached the peak at 4 hours after dinner. The CHD patients had higher postprandial serum RLP-C levels after lunch and dinner, and higher serum TG level after lunch than the controls (P ＜ 0. 05). Conclusion There was no significant difference in the concentration of fasting serum RLP-C between the two groups. However, its concentration changed more significantly at 4 hours after lunch and dinner compared to that of fasting. Therefore, the RLP-C level measured at 4 hours after lunch and dinner may be more practical in clinic.

Objective To explore the changes of residual lipoprotein-cholesterol (RLP-C) after three meals in coronary heart disease group and control group, to explore the best time point for detecting post-prandial RLP-C levels. Methods Thirty-one patients andcontrols were recruited and divided into coronary heart disease group and control group. Vein blood samples were collected at 4 hours of fasting and three meals, and serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) concentrations were measured. Serum RLP-C levels was calculated according to the equation. Results There were no significant differences in serum fasting TC, TG, LDL-C, non-HDL-C and RLP-C levels between CHD patients and controls (P＞ 0. 05). The CHD patients had lower HDL-C concentrations than controls (P ＜ 0. 05). Postprandial serum TG and RLP-C levels increased significantly in CHD patients after each meal (P ＜ 0. 01), and reached the peak at 4 hours after dinner. The CHD patients had higher postprandial serum RLP-C levels after lunch and dinner, and higher serum TG level after lunch than the controls (P ＜ 0. 05). Conclusion There was no significant difference in the concentration of fasting serum RLP-C between the two groups. However, its concentration changed more significantly at 4 hours after lunch and dinner compared to that of fasting. Therefore, the RLP-C level measured at 4 hours after lunch and dinner may be more practical in clinic.

A case of portopulmonary hypertension characterized by repeated syncope was retrospectively analyzed. Intrahepatic or extrahepatic factor-induced portal hypertension complicated with metabolic disorder of vasoactive substances, vascular pressure, inflammation, etc. may result in systolic and diastolic dysfunction of pulmonary arteries and systemic hyperdynamic circulation, the long-term effect of which can induce vascular remodeling and consequently, pulmonary hypertension. The pathogenic process is rather insidious. Pulmonary hypertension is clinically characterized by the raised average pulmonary artery pressure, normal pulmonary capillary wedge pressure and high pulmonary vascular resistance. Currently available therapeutic approaches include drug therapy targeting on pulmonary hypertension and liver transplantation.
Blood Pressure ; Humans ; Hypertension, Portal ; complications ; diagnosis ; Hypertension, Pulmonary ; complications ; diagnosis ; Liver Transplantation ; Syncope ; complications ; diagnosis