1.Analysis of serum gastric function and Helicobacter pylori infection in patients with gastric hyperplastic polyps and gastric fundic gland polyps
Menglan WANG ; Junliang LIU ; Yanhong WANG ; Rui ZHONG ; Sujuan FEI
Clinical Medicine of China 2019;35(5):460-464
Objective To analyze the serum gastric function and Helicobacter pylori ( HP ) infection in patients with gastric hyperplastic polyps and gastric fundic gland polyps.Methods From December 2017 to December 2018, 135 patients with gastric polyps and pathologically confirmed gastric hyperplastic polyps and gastric fundic gland polyps were enrolled in the hospital of Xuzhou Medical University.Among them, 68 patients with hyperplastic polyps, 67 cases of the gastric fundic gland polyps.Serum Hp antibodies ( UreA, UreB, VacA, CagA antibodies ) were qualitatively detected by immunoblotting.Eighty patients with chronic superficial gastritis were selected as the control group.Three groups of serum pepsinogen?I ( PG?I),pepsinogen?Ⅱ( PG?Ⅱ),gastrin were detected by enzyme?linked immunosorbent assay (ELISA).Gastrin?17( G?17) and calculate PGⅠ and PGⅡ ratio( PGR).Results The levels of serum PGⅡ(13.13(8.15,20.30) μg /L) and G17 (8.44(3.72,27.17) pmol/L) in the gastric hyperplastic polyp group were higher than those in the control group (9.16(5.56,15.14) μg/L and 1.83(0.87,5.95) pmol/L) ( P<0.05),and the PGR level was lower than the control group ( P<0.05);serum PGI ( 120.12 ( 86.72,174.70) μg/L), PGII ( 11.92 ( 7.27,22.26) μg/L),G17 ( 5.68 ( 1.79, 14.65) pmol/L) in the gastric fundic gland polyp group was higher than the control group (( 101.32 (79.17,131.33) μg /L,9.16 ( 5.56,15.14) μg /L,1.83 ( 0.87,5.95) pmol/L) ( P 均<0.05)) ( P<0.05); serum G17 (8.44(3.72,27.17) pmol/L) level in gastric hyperplastic polyp group was higher than gastric fundus polyp group (5.68(1.79,14.65) pmol/L) ( P<0.05); Hp infection rate in gastric hyperplastic polyp group61.76%(42/68)was higher than that in the gastric fundic gland polyp group40.30%(27/67) (P<0.05),and type I Hp was the main one (P<0.05).The serum PGⅡ and G17 levels in the gastric hyperplastic polyp group were higher than those of Hp negative ( all P<0.05).There were no significant differences in serum PGI, PGⅡ, G17, and PGR levels between the HP?positive and negative?positive patients in the gastric fundus polyp group.The serum PGI and PGR levels in the hypertrophic polyp group were higher than those in the HPⅡ type ( all P<0.05).There was no significant difference in the levels of serum PGⅠ,PGⅡ,G17,and PGR between the gastric fundic gland polyps group and the type Ⅱ.Conclusion Serum PG and G17 levels in patients with gastric hypertrophic polyps and gastric fundic gland polyps are higher than those in patients with chronic superficial gastritis.Patients with gastric hyperplastic polyps have higher HP infection rate and abnormal gastric function than gastric fundic gland polyps.
2.Assessment of transmission capacity of influenza and effect evaluation of suspension measures in schools and nurseries
XU Yucheng, ZHANG Ruiyin, ZHOU Zhifeng, ZHONG Jianming, CHEN Haochuan, ZHAO Menglan, LI Xueyun
Chinese Journal of School Health 2021;42(2):273-276
Objective:
To estimate the transmission capacity of influenza clustering in schools and nurseries, and to evaluate the effect of suspension measures, providing a basis for formulating disease management strategies and control measures.
Methods:
The SEIAR dynamics model was used to simulate the epidemic data, calculating the basic regeneration coefficient R 0 of the epidemic to evaluate the epidemic transmission capacity, and calculating the cumulative incidence rate of the epidemic to evaluate the prevention and control effect of the suspension measures.
Results:
The basic regeneration coefficient R 0 was 8.44(8.01,8.89) without intervention. There were statistically significant differences in R 0 of influenza epidemic among different types of school(F=9.52, P<0.01). The R 0 of influenza epidemic in primary and secondary schools were higher than that in nurseries(P<0.05). R 0 of influenza A was higher than that of influenza B(t=2.71, P<0.01). R 0 of influenza A(H3) was higher than of influenza B(Victoria)(P<0.05). The cumulative incidence of the outbreaks which were suspended for 4 days and 7 days was significantly lower than that in the non-suspensions(P<0.05). However, there was no significant difference in the cumulative incidence of the outbreaks between the 4-day suspension and the 7-day suspension(P>0.05).
Conclusion
Transmission capacity of school-based influenza epidemic is high, especially among primary and secondary schools. When the epidemic situation of infected class meets the suspension standard, it is recommended to suspend classes for 4 days.
3.Chen Zhiqian's Thoughts on Public Health in the 1920s
Zhexi GONG ; Jinheng LI ; Pu'an CUI ; Menglan LIN ; Zhong HE
Acta Academiae Medicinae Sinicae 2024;46(5):700-705
During his studies at the Peking Union Medical College(1921-1929),Chen Zhiqian formed his thoughts on public health under the influences of modern medical education and the advanced thinking of the times,which laid an ideological foundation for his later engagement in rural health care and reflected the medical progress in China at that time.In the 1920s,Chen Zhiqian's thoughts on public health mainly encompassed five aspects.First,health was a cornerstone of the country's wealth and people's well-being.Second,he belived in comprehensive"big medicine"which emphasized the combination of prevention and treatment.Third,he advoca-ted the return of medicine to the state and the building of a medical system covering all people.Fourth,he advo-cated maternal training and institutional standardization,emphasizing child health protection.Fifth,he was com-mitted to the popularization of health science and advocated health education reform.Summarizing the above five aspects is of great significance for enriching and improving the academic evaluation about Chen Zhiqian and pro-vides a reference for today's work on public health.
4.Exploring the feasibility of narrative medical records:from concept to clinical practice
Fei LI ; Jianli WANG ; Naishi LI ; Liming ZHU ; Jiaxin ZHOU ; Cuiwen FA ; Menglan LIN ; Yongqing HAN ; Chenyanwen ZHU ; Zhong HE ; Xiaohong NING
Chinese Medical Ethics 2024;37(11):1263-1269
Based on the theoretical reflection on the reflective function of medical records,the important findings in the practice of medical records writing in the field of palliative care,and conceptual analysis of narrative medicine tools,combined with empirical investigation materials and analysis,this paper focused on the practice of medical records writing for reflection and research.The main contents include defining the concept of narrative medical records,which are medical records used in clinical practice that incorporate narrative content;clarifying their characteristics and functions at different levels;and exploring practical paths for their application in clinical practice.Based on an in-depth exploration of the uniqueness of narrative medicine practice at Peking Union Medical College,it also emphasized the necessity of writing medical records with narrative thinking.Specifically,it focused on using narrative thinking and forms to enhance the improvement of current medical records writing,and further sought a general framework and multiple possibilities for narrative medicine clinical pathways.
5.Reflection on general and innovative education of palliative care in China
Xiaona QI ; Qiang YAO ; Qinming YU ; Miaomiao ZHAO ; Yan WANG ; Menglan ZHONG ; Lijuan YU
Chinese Medical Ethics 2024;37(3):332-338
With the process of China’s aging population intensifying, palliative care, as an important guarantee for improving the quality of life of terminally ill patients, is receiving more and more social attention, and the demand is constantly increasing. Palliative care needs versatile professionals, and general education can enhance people’s awareness and understanding of it, enabling more people to understand, accept, and participate in palliative care. With the advancement of knowledge and technology in palliative care, the traditional cramming education models are no longer able to meet the actual needs. Therefore, there is an urgent need to innovate palliative care education strategies. By analyzing the current problems in the general education of palliative care in China, this paper proposed thoughts and suggestions for general and innovative education of palliative care in several aspects, such as establishing general and innovative education systems and evaluation systems of palliative care, diversifying educational contents and methods, strengthening medical staffs training, promoting diversified student groups, and strengthening the popularization of palliative care knowledge among the public.