1.Research progress on immune system function damage induced by microwave radiation
Sanya YUE ; Rong WANG ; Yuhua WANG ; Jing LI ; Mengjuan SHANG
Journal of Environmental and Occupational Medicine 2024;41(8):954-960
With the rapid advancement and wide application of microwave technology, it enhances convenience while potentially endangering health. The immune system, as a vital shield, is an important protective barrier and also one of the sensitive targets of microwave radiation. The immune system is particularly affected by microwave radiation via innate and adaptive immune responses, which is supported by both population surveys and experimental studies; however, the precise mechanism of immunotoxicity of microwave radiation remains under investigation. In light of recent scientific advances in the correlation between microwave radiation and the immune system, the deleterious impact of microwave radiation on innate immunity was delineated. Microwave radiation can induce irregular innate immune function by damaging macrophages, neutrophils, natural killer cells, and dendritic cells. The effects of microwave radiation on adaptive immunity were also elucidated. Microwave radiation can impair cellular immune response by influencing T cell proliferation, maturation and activation, and distribution of T cell subpopulation, and also hinder humoral immune function by influencing B lymphocyte protein expression, maturation during development, and number of B cells. Disparity in the immune function of the body can precipitate the onset of various immune-associated diseases, so the immunotoxic effects of microwave radiation and associated protection need considerable attention and detailed investigation. This article reviewed the shortcomings of existing studies, and suggested that future experimental studies should use experimental parameters that are more similar to the actual scene of life and work, pay more attention to the biological effects of combined multi-frequency microwave exposure on the immune system, use standardized and unified experimental methods, and incorporate more sophisticated experimental technologies to further elucidate the laws of damage effect and exact mechanism of microwave radiation on the immune system, so as to provide a scientific basis for potent protection against the damage effect of microwave radiation on the immune system.
2.Advances in research on microwave radiation-induced reproductive system damage and its treatment
Rong WANG ; Sanya YUE ; Jing LI ; Mengjuan SHANG
Chinese Journal of Radiological Medicine and Protection 2024;44(7):633-640
Microwave technology has been widely applied in various fields such as military affairs, communication, transportation, medical treatment, and industrial and agricultural production. Nevertheless, such technology poses potential threats to human health while bringing convenience to production and life. Previous studies have shown that the reproductive system is one of the most sensitive targets to microwave radiation, and its microwave damage effect and treatment have garnered wide concern. This paper reviews the recent domestic and foreign studies on the impacts of microwave radiation on reproductive health and its treatment, especially the damage effects, mechanisms, and treatment method, from the aspects of epidemiological investigations and animal experiments. The purpose is to provide suggestions and references for future research on the effects of microwave radiation on reproductive damage and its treatment.
3.Effects of microwave radiation on learning and memory and neurotransmitters in the hippocampus
Dan DU ; Mengjuan SHANG ; Jiajin LIN ; Xia MIAO ; Yuming YAN ; Shenglong XU ; Na SUN ; Jing LI
Chinese Journal of Radiological Health 2023;32(2):209-215
The central nervous system is one of the most sensitive targets of microwave radiation. Microwave radiation can affect spatial learning and memory and neural information transmission. The effects of microwave radiation on neurotransmitters in the hippocampus and the underlying mechanisms are still unclear. This paper reviews the effects of microwave radiation on learning/memory and neurotransmitters as well as the mechanisms of action on neurotransmitters. This paper aims to provide a scientific basis for future research in this area.