1.Biblio Metrics Analysis on Apoplexy
International Journal of Traditional Chinese Medicine 2008;30(2):97-100
By collecting literatures on apoplexy recorded in"Database of Basic TCM disease"from 2001 to 2005,we statistically analyzed changes on volume of documents,major authors,major journals,and contents of study in these literatures.
2.The role and significance of Traditional Chinese Medicine Thesaurus of China
Jinong CHU ; Li PENG ; Meng CUI ; Jing ZHANG
International Journal of Traditional Chinese Medicine 2014;(12):1060-1063
This article briefly reviews the development of Traditional Chinese Medicine Thesaurus of China. As a professional thesaurus on TCM, its status and role in the database construction, literature retrieval, cataloging, periodicals indexing and information standardization were discussed. Its significance in the medical information organization, and data resource integration were described in this paper.
3.Investigation and Comparison on Traditional Chinese Medicine Terminology Standards
Yuanbai LI ; Meng CUI ; Yang YANG ; Xiaobo ZHU ; Chaojie LIAN ; Meng LI ; Jing ZHANG ; Huaiping XI ; Hongming MA ; Na ZU
World Science and Technology-Modernization of Traditional Chinese Medicine 2013;(7):1592-1595
In this article, the Chinese Traditional Medicine and Materia Medica Subject Headings, Standards of the People's Republic of China - Classification and Codes of Diseases and Zheng of Traditional Chinese Medicine and the Chinese Terms in Traditional Chinese Medicine and Pharmacy were compared. Three standards were compared from the terminology quantity, content and classification. Each standard has its special feature. The compatibility and consistency are not strong in these standards. More authoritative traditional Chinese medicine terminology standards need to be established for the application in the clinical practice and scientific research.
4.Optimization of electroporation parameters in HL-60 cells for STIM1 siRNA interference during its differentiation.
Hai-Yang CHEN ; Wen-Ying ZOU ; Cui-Hua XIE ; Xiao-Jing MENG ; Chun-Qing CAI
Chinese Journal of Applied Physiology 2011;27(4):497-499
Cell Transformation, Neoplastic
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drug effects
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genetics
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Dimethyl Sulfoxide
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pharmacology
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Electroporation
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methods
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HL-60 Cells
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Humans
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Membrane Proteins
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genetics
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Neoplasm Proteins
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genetics
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RNA Interference
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RNA, Small Interfering
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genetics
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Stromal Interaction Molecule 1
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Transfection
5.Analysis of Microbia sensutivity tests in 130 Mycobarterium tuberculosis strains
Yansheng TIAN ; Xingkun CUI ; Lingbao MENG ; Dongni DU ; Li ZHANG ; Jing WANG ; Guoqing ZHANG ; Hongguang LI
Chinese Journal of Laboratory Medicine 2001;0(04):-
Objective To explore the characteristics of mycobacterium dependend antituberculous drug. Methods 137 strains of mycobacterium were tested for resistance by the absolute concentration method on Lowenstein Jensen medium. Dependent positive were the coloun that on higher concentration drug medium stronger than lower concentration than controls. Results 12(8.76%) of the 130 strains M. tuberculosis and 7 strains nontuberculous mycuberculous (NTM) were found dependent, in which strains dependend on INH, RFP and SM were 3(2.19%), 10(7.3%) and 3(2.19%) respectively, 4(2.92%) were dependend on two drugs. Conclusions Were NTM dependent, Not found all detected from multiple strains.
6.Validation and reliability of a Chinese version of Death Attitude Profile-Revised
Lu TANG ; Lingjun ZHOU ; Jijun ZHAO ; Yuxiang LI ; Ling ZHANG ; Jing CUI ; Xianli MENG
Chinese Journal of Practical Nursing 2014;30(22):37-40
Objective To develop a Chinese version of Frommelt Attitude Toward Care of the Dying scale (FATCOD) and evaluate its validity and reliability to provide a tool for the field of hospice care and death education used among nurses.Methods FATCOD scale was adopted according to Brislin's translation model for cross-cultural research and its reliability and validity of the new Chinese version was tested in 126 nurses.Factor analysis and correlation analysis were applied to establish the validity and reliability.Results The Chinese version of FATCOD scale consisted of 30 items.The Cronbach's α coefficient of the scale was 0.828; split-half coefficient of the whole scale was 0.807; the varimax rotation factor analysis of the scale identified twelve principal factors and explained for 69.5% variances.Conclusions The Chinese version of FATCOD scale is valid and reliable in the sample of nurses,and can be used in the field of hospice care and death education.
7.Novel drug composition ameliorating thrombosis and its molecular mechanisms.
Meng NING ; Jing-Hui HUANG ; Yan-Fang ZHANG ; Wen-Yu CUI ; Hai WANG
Chinese Journal of Applied Physiology 2014;30(2):184-188
OBJECTIVETo investigate the antithrombotic effects and its molecular mechanisms of prazosin combined with anisodamine (Ani).
METHODSIsolated rat tail artery rings model was employed to evaluate the vasodilative effects of drugs, mice tail thrombosis model induced by carrageenan was used to study the antithrombotic effects and its molecular mechanisms of the drug composition.
RESULTSAmong alpha1-adrenoreceptor antagonists, prazosin(Pra) had the greatest relaxation rate, which was (82.6 +/- 8.9)%, and the EC50 value was 0.44 micromol/L. The drug composition of anisodamine and prazosin of different doses could decrease the length of the tail thrombosis from (24.6 +/- 4.6)mm to (6.9 +/- 2.7)mm, and the rate of thrombosis was decreased from 86.6% to 50.0%. The drug composition could prolong the prothrombin time (PT) distinctively, but it had no effect on the activated partial thromboplastin time (APTT). It also could restrain the decrease of serum levels of tissue plasminogen activator (t-PA) and 6- Keto -PGF1alpha as well as the increase of type-1 plasminogen activator inhibitor (PAI-1) and thromboxane B2 (TXB2) in the mice.
CONCLUSIONThe drug composition formed by anisodamine and prazosin has good effects of relaxing extremities tiny blood vessels and it can fight against thrombosis, its antithrombotic mechanisms may be related to the influence of the extrinsic coagulation pathway, inhibition of platelet activation functions and the promotion of fibrinolysis function.
Adrenergic alpha-1 Receptor Antagonists ; pharmacology ; Animals ; Disease Models, Animal ; In Vitro Techniques ; Male ; Prazosin ; pharmacology ; Rats ; Rats, Wistar ; Solanaceous Alkaloids ; pharmacology ; Thrombosis ; drug therapy
8.On the important role of Siguan points in treatment of chronic fatigue syndrome.
Jing-jing WANG ; Hong MENG ; Cheng-bin CUI ; Yu-jing SONG ; Xiao-hong WANG ; Zhong-chao WU
Chinese Acupuncture & Moxibustion 2006;26(2):116-119
OBJECTIVETo probe into the role of Siguan points in treatment of chronic fatigue syndrome.
METHODSBased on diagnosis, pathogenesis and etiology of chronic fatigue syndrome in TCM, the role of Siguan points in treatment of chronic fatigue syndrome were induced by means of relative literatures of Siguan points in recent 10 years from 3 aspects.
CONCLUSIONAcupuncture at Siguan as main points has a better therapeutic effect on chronic fatigue syndrome.
Acupuncture Points ; Acupuncture Therapy ; Fatigue Syndrome, Chronic ; therapy ; Humans
9.Fludarabine combined with pirarubicin chemotherapy for patients with relapsed or refractory indolent non-Hodgldn lymphoma
Huaqing WANG ; Lihua QIU ; Zhengzi QIAN ; Wei LI ; Xingrui MENG ; Yun HOU ; Zheng SONG ; Jing ZHAO ; Xiuzhen CUI ; Xishan HAO
Journal of Leukemia & Lymphoma 2009;18(10):609-611,615
Objective To evaluate the efficacy and safety of fludarabine and pirarubicin (FT) regimen in the treatment of refractory or relapsed indolent non-Hodgkin lymphoma (NHL). Methods A total of 40 patients with relapsed or refractory indolent NHL were treated with FT regimen, one cycle for 28 days, total 6 cycles. The data of indolent NHL patients treated with fludarabine, noventrene and dexamethasone (FND) regimen were collected as control. Results 40 patients were given 228 cycles chemotherapy, overall response rate was 62.5 %, median progression-free survival was more than 20 months and 2 years overall survival rate was 70.0 %. The main toxicities was leucopenia (80.0 %), but the incidence of WHO Ⅲ-Ⅳ leucopenia and pneumonia was less than that of in the control group, the rate were 12.5 % vs 29.0 % and 2.5 % vs 23.0 % respectively (P <0.05). Conclusion The efficacy of FT regimen was as good as FND regimen, but the incidence of leucopenia and pneumonia by Ⅲ-Ⅳ was lower in FT group than in FND group. So the FT regimen was an effective and safe second-line salvage regimen for relapsed or refractory indolent non-Hodgkin lymphoma.
10.The effect of hypothermia on the vasoconstriction and vasodilatation and concerned with vasoactive drugs.
Wen-Zhi HAN ; Meng NING ; Jing-Hui HUANG ; Wei LIU ; Yan-Fang ZHANG ; Wen-Yu CUI ; Hai WANG
Chinese Journal of Applied Physiology 2014;30(3):204-207
OBJECTIVETo investigate the changes of vasoconstriction and vasodilatation under different temperature conditions and the protective effects of Vitamin E (Vit E) against endothelial injury induced by hypothermia.
METHODSThe tail arterial rings were prepared for isometric tension recording using multi wire myograph system. The effect of temperature on relaxation and construction was evaluated. Incubate the arterial rings with different concentration of Vit E when they were exposed to hypothermia, then acetylcholine (ACh)-induced endothelium-dependent relaxation was investigated to evaluate the activity of endothelial.
RESULTS(1) The hypothermia could enhanced the dose-dependent construction induced by PE in mice tail artery. (2) Exposure to hypothermia also resulted in increase of sodium nitroprusside (SNP)-induced re-After incubation with Vit E, the vascular relaxation responses to ACh increased in an endothelium-dependent manner, when compared with the hypothermia-treated group.
CONCLUSIONThe vascular function of constriction was attenuated by hypothermia, while the relaxation was increased. Vit E could prevent the hypothermia-induced decrease in vascular endothelial cells.
Animals ; Arteries ; drug effects ; physiology ; Cold Temperature ; Hypothermia ; In Vitro Techniques ; Male ; Mice ; Prazosin ; pharmacology ; Solanaceous Alkaloids ; pharmacology ; Vasoconstriction ; drug effects ; Vasodilation ; drug effects ; Vasodilator Agents ; pharmacology ; Vitamin E ; pharmacology