Objective:To investigate the routine maintenance and inspection methods of magnetic resonance imaging (MRI) equipment, reduce the failure rate and improve the image quality, and ensure the normal operation of medical image diagnostic equipment.Methods:According to the characteristics of the equipment, to make maintenance inspection goals and complete the daily management of MRI equipment. According to the medical equipment management system requirements, to establish and maintain records to provide data to meet the requirements and the effective operation of quality management system, and to record the data for each equipment for continuity and traceability.Results: There are the potential problems through the management and analysis of MRI equipment data. And the problems were timely solved to make the device operate steady. It’s easy to get a clear and reliable image and to provide an objective and true diagnostic basis for clinical.Conclusion: The routine maintenance and inspection of MRI equipment is an indispensable and important work in medical engineering.

Objective: To study the relationship between negative behavior of preschool children and behavior of their mothers. Method.. 742 mothers of children in their 3 ～ 6 year old age were tested by self- made questionnaire. Results: Negative behavior was not significantly related to age and gender of children. It was negatively related to maternal supporting behavior and positively to maternal un- supporting behavior. The culture background (urban/rural), family income and mother' s occupation were found to be important factors mediating maternal un- supporting behavior. Conclusion: Negative behavior of preschool children is influenced by mother' s behavior, which in turn has its cultural - economical background.

Objective To understand the current situation of multidrug-resistant organism (MDRO)infection in hospitalized patients in a tertiary first-class hospital,as well as efficacy of bundle intervention measures on preven-tion and control of infection. Methods Hospitalized patients who were infected with MDROs in this hospital during 2012-2014 were monitored and conducted bundle intervention. Results In 2012-2014,a total of 1909 MDRO strains were isolated. The isolation rates of MDROs in 2012-2014 were 30.69% ,31 .04% ,and 29.40% respec-tively,bedside intervention rates were 81 .02% ,92.05% ,and 94.23% respectively,implementation rates of clinical isolation were 69.97% ,82.98% ,and 93.04% respectively;MDRO isolation rates during 2012-2014 were not sig-nificantly different(P>0.05);bedside intervention rates and implementation rates of clinical isolation were both sig-nificantly different(both P<0.05). The top 3 isolated MDROs in 2012-2014 were extended-spectrumβ-lactamases (ESBLs)-producing Escherichia coli,multidrug-resistant Acinetobacter baumannii,and ESBLs-producing Klebsiel-lapneumoniae. Conclusion Bundle intervention measures,such as multi-department collaboration and strengthened on-site supervision,can promote more standardized management of healthcare-associated infection,enhance the im-plementation rate of clinical isolation,and effectively prevent and control the spread of MDRO in hospital.

DNA ; chemistry ; Genes ; Genes, erbB-2 ; Humans ; Pathology ; trends

The clinician training system in Japan is different from that in China as their medical students are allowed to take medical doctor examination immediately following their graduation.But they must undergo at least two years of training in basic clinical knowledge and skills prior to taking any clinical practice.This training system is inspirational for us as follows:China should include standardized training of residents into the law of medical practitioners,and medical graduates must take two years of knowledge training in full medicine before they are qualified for clinical practice.On top of this training,they need to undergo at least three years of specialized doctor training,making them competent clinicians with comprehensive knowledge coverage and outstanding skills in specific areas following such staged training.

Objective: To revise a coping style scale for adolescents and analyze the characteristics of adolescents' coping style.Methods: 1013 middle school students were sampled for the research: 783 for the explosive factor analysis and T test,while the other 330 for the confirmative factor analysis.Results: 5 factors were extracted through EFA and explained 45.17% of the variance.The results of CFA showed satisfactory construction validity: RMSEA = 0.067.The results of T tests for the effects of different age,gender,family type were significant.Conclusion: The Coping Style Scale for Adolescents achieves satisfactory reliability and validity;the adolescents' coping styles are influenced by age,gender and one-child family.

Objective: To evaluate the clinical effect of the double-orifice technique in the treatment of the anterior leaflet prolapse of mitral valve. Methods: 35 patients with severe anterior leaflet prolapse of mitral valve underwent valve repair using the double-orifice technique. The condition of valve was assessed with echocardiography preoperatively, intraoperatively, and postoperatively. Results: The mean postoperative valve area was (4 1?1 8) cm 2 against the preoperative valve area of (8 3?1 6)cm 2. Mild regurgitation was found in 2 patients after operation. There were no hospital deaths. At the latest follow-up, the heart function was improved significantly in all patients (NYHA class I). Echo-Doppler assessment of valve showed stable valve function in all patients. There were no late stenosis of valve and no late death. Conclusion: The results of this study show that the double-orifice technique is a safe and effective method for treatment of anterior leaflet of mitral valve with low mortality and morbidity, and excellent early and mid-term results.

Objective To investigate the clinical features,treatment and prognosis of paraneoplastic pemphigus (PNP).Methods A retrospective study was performed on 11 patients with PNP hospitalized in the Department of Dermatology,Ruijin Hospital.Clinical characteristics of these patients were analyzed.Results Of the 11 patients,10 had oral or labial erosions or ulcers,and 6 had obstructive bronchiolitis.Computed tomography (CT)showed solitary internal tumors in all the patients after appearance of skin lesions,and 8 of them were diagnosed with Castleman's disease.All the patients had been treated with corticosteroids before operation,but achieved no obvious improvement.After 2-7 months of postoperative treatment with low-dose prednisone and thalidomide,both cutaneous and mucosal lesions healed with the relief of pulmonary symptoms in 5 patients.Conclusions Oral erosions or ulcers appear to be the most common initial manifestation of PNP with Castleman's disease as the most frequent accompanying tumor.Early detection and timely resection of tumors are keys to successful treatment of PNP,and postoperative treatment with glucocorticoids and thalidomide proves to be effective for PNP.

Objective To explore the pathogenesis and clinical value of Th1/Th2 and normal intestinal flora from the angle of immunological and intestinal micro environment balance by detecting the plasma interferon-γ(IFN-γ)and interleukin-4(IL-4)and fecal bifidobacteria in Children with Allergic Asthma,so as to provide a theoretical basis through early intervention of probiotics to correct the Th1/Th2 balance.Methods The levels of blood plasma IFN-γ,IL-4 and fecal bifidobacteria amount of 165 cases of chil-dren with allergic asthma and 150 health students as control group were detected by ELISA and real time fluorescence PCR at the same time.Retesting these above indexes after applying bifidobacteria regulation of intestinal flora for 6 months.The clinical relative factors and experimental data were statistically analyzed.Results The level of IFN-γof asthmatic children were remarkably lower than those in the control group(P <0.05),while the level of IL-4 of asthmatic children were remarkably higher than those in the control group(P <0.05),and the amount of bifidobacteria of asthmatic children were remarkably lower than those in the control group(P <0.05).The level of IFN-γand bifidobacteria of asthmatic children improved remarkably and the level of IL-4 decreased significantly after applying bifidobacteria regulation of intestinal flora for 6 months.All of them had remarkable statistically signifi-cant.Conclusion The immune balance was affected by the intestinal flora balance of vice versa.This would provide an important theo-retical support to prevent the occurrence of allergic asthma by the early probiotics regulation of intestinal flora and immune balance.

Objective To investigate the relationship of pulmonary function and metabolic indexes in overweight as well as obesity people.Methods Three hundred and five health examination adults were selected as our subjects.The basic parameters,metabolic indexes and pulmonary function were measured.Of which,pulmonary function indexes include forced vital capacity (FVC),forced expiratory volume in one(FEV1),peak expiratory flow(PEF),the ratio of the forced expiratory volume in the first one second to the forced vital capacity (FEV1/FVC),the ratio of the forced expiratory volume in the first one second to the vital capacity(FEV1/VC),maximal expiratory flow after 50％ of the FVC (MEF50),maximal expiratory flow after 25％ of the FVC (MEF25),and each index value of lung function was expressed the ratio of the measured value/the predictive value.Metabolic indexes include triglycerides (TG),total cholesterol (TC),low-density lipoprotein cholesterol (LDL-C),fasting plasma glucose (FPG)),C-reactive protein (CRP),high-sensitivity C-reactive (hs-CRP),superoxide dismutase(SOD),systoloc blood pressure (SBP) and diastolic blood pressure (DBP).Statistical analysis methods include one-way analysis of variance and Spearman correlation analysis.Results The levels of FVC,FEV1,FEV1/FVC in overweight and the obesity group were (85.74 ± 13.94)％ and (82.85±13.34)％,(84.52 ± 14.62)％ and (82.74 ± 14.18)％,(103.40 ± 13.05)％ and (103.17 ±8.99)％respectively,lower than that of normal weight group [(95.79 ± 26.83) ％,(92.65 ± 26.93) ％,(99.98± 11.88) ％,all P values less than 0.05)].Compared with the normal weight group,the levels of TG,SBP,FPG in overweight group and the obesity group were significantly increased.The levels of LDL-C,DBP,hs-CRP in obesity were (5.05 ± 0.83) rmtmol/L,(86.64 ± 10.49) mmHg,(3.74 ± 5.51) mg/L respectively,higher than that of normal group [(3.08 ±0.96) mmol/L,(77.69 ± 13.20) mmHg,(2.33 ±4.67) mg/L,P ＜0.05)].SOD activities in overweight and obesity group were (140.82 ± 13.16),(144.89 ± 13.82) U/L respectively,significantly lower than that of normal weight group[(148.64 ± 14.94) U/L,P ＜0.05)).The levels of SBP,DBP,hs-CRP in the over weight group were (127.77 ± 19.07) mmHg,(80.87 ± 12.21) mmHg,(2.31± 3.73) mg/L),higher than that of obesity group.Among metabolic indices,TG,SBP,DBP,FBG,CRP,hs-CRP and SOD were related with FVC (r =-0.129,-0.129,-0.136,-0.180,-0.220,-0.217 respectively,P ＜ 0.05 or P ＜ 0.01).There was negatively correlated relationship between SBP,FBG,CRP,hs-CRP and FEV1 (r =-0.128,-0.127,-0.148,-0.198 respectively,P ＜0.05 or P ＜0.01),So were SBP,CRP,hs-CRP and PEF (r =-0.137,-0.117,-0.133 respectively,P ＜ 0.05).Negatively correlated relationship between hsCRP,SBP and MEF50 were seen (r =-0.126,-0.124,P ＜ 0.05).Meanwhile there was negatively correlated relationship between SOD and FVC,FEV1/FEV,PEF,MEF50 (r =0.149,0.094,0.119,0.141,0.129respectively,P ＜ 0.05 or P ＜ 0.01).Conclusion Impaired pulmonary function and metabolic disorders were showed in the overweight and obesity people.Metabolic indexes were related with pulmonary function.