Aggressive Periodontitis ; diagnosis ; therapy ; Humans

Humans ; Optical Imaging

Liver blood flow was measured in normal & CCl4-intoxicated mice & rats, using the electrolysis-generated hydrogen gas method. The results showed that the intramuscular injection of 6-15/kg of ISM increased significantly the liver blood flow in normal mice & rats. In acute or chronic CCl4-intoxicated mice & rats, the liver blood was decreased but the blood flow was restored the normal level by the ISM. In addition, the protective effect against liver injury was also observed by the histological examination & electron micrographs.The above results suggest that the protective effect of ISM against CCl4-induced liver injury seems to be through increasing the liver blood flow, improving liver's microcirculation & preventing or mitgating the denaturing or necrosis of liver cells.

AIM:To study characteristic components and fingerprint of the essential oils of processed Rhizoma curcumae longae,and further use as one of evaluation of quality control. METHODS:The essential oils were ex-tracted by steam distillation from ten batches of samples,and the characteristic components of the essential oils were analysed by GC-MS. And then mutual fingerprint of the characteristic components was established by Microsoft Office Excel 2003. RESULTS:Twenty-seven characteristic components of essential oil consisted of Ar-turmerone,Tumerone,Curlone,?-Curcumene,?-Zingiberene,?-Sesquiphellandrene and their derivatives,which were compose of about 88. 8% ～94. 9% of the total essential oil. The retention time and peak area of the components appeared the characteristic fingerprint. CONCLUSION:The method and the fingerprint have a good reproducibility,and can be used to identify and evaluate the quality of processed Rhizome curcumae longae.

ObjectiveTo explore the relation between personality and depression in elderly,particularly to investigate mediating effect of positive psychological resource.MethodsThe eysenck personality questionaire-revised short scale for Chinese(EPQ-RSC),self-rating depression scale(SDS) and scales for positive psychological resource were performed by 270 elderly in community of Tianjin.Then correlation analysis,regression analysis and path analysis were accomplished to explore association between those variables.Results Neuroticism and Psychoticism personality correlate positively with depression ( r=0.45,0.48) and contribute about 30％ variance of it (F=49.95 ).Positive psychological resource such as optimism,resilience and self-efficacy correlated negatively with depression ( r =- 0.41,- 0.39,- 0.20 ) and contributed 19％ variance of it (F =30.02 ).The results of path analysis showed positive psychological resource mediated the relation between personality and depression also.ConclusionNeuroticism and Psychoticism are important risk factors of depression in elderly.Positive psychological resource such as optimism,resilience and self-efficacy are key protecting factors for depression and they mediate the relation between vulnerable personality and depression.

Objective To evaluate the effects of moderate oxygen concentration (40％ O2) on A549 cells and expression of transforming growth factor-β1 (TGF-β1) mRNA and connective tissue growth factor (CTGF) mRNA in A549 cells.Methods Cultured A549 cells were seeded in 6-well plates (1 mYhole) or in 10 cm diameter dishes (5 ml/dish) with the density of 1 × 1O5 cells/ml and randomly divided into 3 groups (n =12 each) using a random number table:control group (group C),40％ oxygen concentration group (group 40％ O2),and 95％ oxygen concentration group (group 95 ％ O2).A549 cells were exposed to air,40 ％ O2 and 95 ％ O2 for 48 h in C,40％ O2 and 95％ O2 groups,respectively.The necrosis and expression of TGF-β1 mRNA and CTGF mRNA were detected at the end of culture.Results Compared with group C,the necrosis rate was significantly increased,while the expression of TGF-β1 mRNA and CTGF mRNA was up-regulated in 40％ O2 and 95％ O2 groups (P ＜ 0.05).Compared with group 95 ％ O2,the necrosis rate was significantly decreased,while the expression of TGF-β1 mRNA was down-regulated (P ＜ 0.05),and there was no significant difference in CTGF mRNA expression in group 40 ％ O2 (P ＞ 0.05).Conclusion Exposure to moderate oxygen concentration for a certain time can induce damage to A549 cells,but the severity is lighter than that caused by high oxygen concentration,and up-regulation of TGF-β1 and CTGF gene expression may be involved in the mechanism.

Objective To gain more pathophysiolgic knowledge about acute obstructive hydrocephalus and to explore its rapid and effective treatment by establishing canine acute obstructive hydrocephalus model.Methods Acute obstructive hydrocephalus model was established by injecting cyan-acrylic gel glue into the fourth ventricle via posterior fosse craniotomy in 9 male adult mongrel dogs.At the same time,lateral ventricle catheterization were performed and were fixed on the scalp to connect reservoir bag so that the changes of intracranial pressure (ICP) could be measured dynamically,and the changes of neurological function were observed.Results Acute obstructive hydrocephalus model was successfully established in 6 of the total 9dogs.ICP was (48.2 ± 6.1 ) cm H2 O at 48 hours after the injection and was (56.4 ± 5.7 ) cm H2 O at 72 hours after the injection,it increased 392％ and 459 ％ respectively.And the ICP after injection was significantly different(P ＜ 0.01 )compared with that before injection (12.3 ± 3.1 )cm H2O.Conclusion The establishment of acute obstructive hydrocephalus model has high success rate,and is easy to reduplicate; ICP could be measured dynamically and also could be reduced by releasing CSF;Thus,ventricular drainage is the most rapid and effective treatment for acute obstructive hydrocephalus.

This study was carried out to observe the hemodynamic changes in patients with BuddChiari syndrome(BCS) during venoauricular bypass. Twenty-one patients with BCS,ASA grade Ⅱ-Ⅲ, aged 33.4 years on average, were involved. The anesthesia was induced with intravenous midazolam, fentanyl and atracurium. The hemodynamic parameters were measured by Swan-Ganz catheter at various times during whole procedures. As cdmpared with those before anesthesia. CO, CI, SI, LVSWI and RVSWl reduced significantly following general anesthesia(P

OBJECTIVE:To introduce a self-cure method for the cough caused by cold.METHODS:By placing control group and trial group,30 cases(control group)were assigned to receive Dextromethorphan Hydrobromide oral liquid and 32 cases(trial group)to employ self-cure method for cough caused by cold.And a self-cure method for the cough caused by cold was induced.RESULTS & CONCLUSION:The practice of self-cure method can speed up the self-cure of cough caused by cold and this method deserves to be popularized.

Objective:With the development of the medical model, huge changes have also occurred in current nursing practice. This study focused on the evaluation of "excellent nurses" working in hospital. Also, the study also aimed to examine differences among doctors, nurses and patients in their ratings. Methods: 630 doctors, 660 nurses, 552 patients completed an evaluation questionnaire for rating excellent nurses. Results: The questionnaire contained items reflecting important characteristics pertaining excellent nurses. Conclusion:There were significant differences between doctors, nurses, and patients in their ratings of excellent nurses.