1.Clinical investigation of knee osteoarthritis with metabolic syndrome
Chinese Journal of Rheumatology 2014;18(11):758-761
Objective To explore the morbidity and clinical characteristics of knee osteoarthritis (OA) complicated with metabolic syndrome (MS).Methods Four hundred and ten patients with knee OA were enrolled into this survey.The subjects were divided into two groups:those with knee OA only:those with both OA and MS.Clinical data in the two groups were evaluated.Results The prevalence of MS was 40.2% in all knee OA patients,there was significant difference between the two groups according to the ratio of male to female (x2=5.853,P=0.001),but no difference between the two groups according to age distribution respectively (P>0.05).For metabolic parameters,waist circumference,triglyceride (TG),low density lipoprotein cholesterol (LDL-C),systolic blood pressure and glycosylated hemoglobin (HbA1c) were significantly increased in the group with both of the two diseases (OA and MS),comparing with those with knee OA only (t=3.123,4.679,2.818,3.697,2.632,2.907,P<0.05).However,there was no difference in both group in serum total cholesterol (TC),high density lipoprotein cholesterol (HDL-C) and fasting plasma glucose level (P>0.05).Incidence of coronary heart disease,diabetes mellitus and hypertension was higher in the group with both OA and MS than that in knee OA only group (x2=6.676 and 104.12,P<0.05).The incidence of diabetes mellitus was not different between the two groups (P>0.05).Conclusion The incidence of metabolic syndrome in knee OA patients is relatively high.Effective treatment should be invited to treat knee OA with MS.
2.Relationship between plasma anti-β2-glycoprotein Ⅰ and cardiovascular disease in systemic lupus erythematosus
Chinese Journal of Rheumatology 2012;16(6):414-417
Objective To investigate the relationship between plasma anti-β2-glycoprotein I (anti-β2-GP I )and cardiovascular disease (CVD) in systemic lupus erythematosus (SLE).Methods Eighty-onepatients with SLE [the mean age was (45±18) years old,among whom 73 were female and 8 were male] and20 controls [the mean age was (43±17) years old,among whom 14 were female,and 6 were male] wereenrolled.Plasma anti-β2-GP I was measured by ELLSA.The relationship between plasma anti-β2-GP I level and CVD in SLE patients was investigated with Logistic regression model.T-test,x2 test,Spearman's correlations and Logistic regression analysis were used for statistical analysis.Results Mean plasma anti-β2-GP I increased significantly in SLE group compared to control group [ (29± 19) vs (14±8) U/ml,t=2.035,P<0.05].The plasma levels of anti-β2-GP I were higher in SLE patients with CVD than those without [(41±25)vs (18±12) U/ml,t=2.038,P<0.05].Plasma anti-β2-GP I level was positively correlated with triglyceride (r=0.337,P<0.05) and renal lesions (r=0.489,P<0.01 ).Plasma anti-B2-GP [ level was negatively correlated with high density lipoproteins (r=-0.385,P<0.05 ) and complement (r=-0.497,P<0.05 ) level.Logistic regression analysis showed that plasma anti-β2-GP I (β=0.675,95%CI0.5070.816,P<0.05) was an independent risk factor for CVD in SLE patients.Conclusion The level of plasma anti-β2-GP I in SLE patients with CVD is high,and it may play a role in the pathogenesis and progression of CVD in SLE patients.
3.The application of PET/CT to predict prognosis of radiotherapy of NSCLC
Chinese Journal of Radiation Oncology 2016;(3):288-291
Conventional CT plays an important role in the diagnosis, staging, radiotherapy target delineation, and prognosis of NSCLC, but it still has many limitations.PET/CT has been widely used in the diagnosis and treamtent of lung cancer.In particular, PET/CT metabolic parameters have great guiding significance in the prognosis of NSCLC patients undergoing radiotherapy, and may be superior to many clinical indices.This review summarizes the advances in the application of PET/CT in the prognostic evaluation of NSCLC patients undergoing radiotherapy.
5.Follow-up for lung function of patients with acute chlorine poisoning after recovery.
Chinese Journal of Industrial Hygiene and Occupational Diseases 2008;26(7):426-427
Adult
;
Aged
;
Chlorine
;
poisoning
;
Female
;
Follow-Up Studies
;
Humans
;
Lung
;
physiopathology
;
Male
;
Middle Aged
;
Young Adult
6.Clinical Study of the Multi-organ Lesions and the Occurrence of Coronary Aneurysms of 92 Pediatric Inpatients with KD.
Daiming ZHENG ; Xiaohui MENG ; Zhiwei GAO
Journal of Medical Research 2006;0(01):-
Objective To investigate the multi-organ lesions and the occurrence of coronary aneurysms in children with Kawasaki disease(KD).Methods 92 pediatric inpatients with KD were enrolled and studied.The organs involved and coronary aneurysms(CAA)were determined by checking blood routine,urine routine,stool routine,chest X-ray,electrokardiogram,liver function,echocardiogram,and clinical manifestation.Results The incidence of various organs involved in 92 patients with KD:heart 71.7%;lung 37.0%;liver 34.8%;brain 12.0%;kidney 18.5%;gastrointestinal tract 15.2%;spleen 2.2%;gallbladder 1.1%;joints 9.8%.In addition,the rate of two organs involved simultaneously was 40.2%,three and more 34.8%.The incidence of CAA in brain lesion,joints lesion and pericardial effusion complications of KD was 45.5%,44.4%,and 41.7%,respectively.Conclusions The data shows that the incidence of heart involvement in the sick-children with KD is highest,and other organs,such as lung,liver,kidney,gastrointestinal tract,brain and joints are involved in turn.The incidence of 2 and more organs involved simultaneously amounts to75.0%.CAA is the most serious complication of KD.Our study suggests that the incidence of CAA is obviously high in these lesions of brain,joints and pericardial effusion involvement in KD.
7.Familial adenomatous polyposis-associated desmoid tumors
Zheng LOU ; Enda YU ; Ronggui MENG
Academic Journal of Second Military Medical University 1985;0(05):-
Desmoid tumor(DT),a rare benign tumor sometimes with local invasion,is more frequently seen in patients with familial adenomatous polyposis(FAP) than in the general public,which might be associated with surgical trauma,genetic predisposition and hormonal factors.Fifty percent of FAP-associated DTs are intra-abdominal,usually present as non-tender,slowly growing masses.The symptoms include abdominal pain,vomiting and diarrhea,etc.Mesenteric DT can cause obstruction and ischemia of intestine,hydronephrosis and fistula.Diagnosis can be made through biopsy or CT scanning.Surgery should be considered for the abdominal wall DTs and medicine is the first choice for mesenteric DTs.Surgery should be chosen with caution.
8.An analysis of HIV/AIDS related knowledge and attitude among four population groups in Rizhao city in 2005
Hongtao WANG ; Qi ZHENG ; Xiangping MENG
Chinese Journal of AIDS & STD 2007;0(03):-
Objective To understand HIV/AIDS related knowledge and attitude among different population groups in Rizhao.Method Self-designed questionnaires were used to investigate HIV/AIDS related knowledge and attitude among rural and urban residents,hotel attendants and government officers.Results The rates of right answers on HIV/AIDS related questions among the government officers,the urban residents,the hotel attendants and the rural residents were 83.38%,72.45%,72.33% and 66.36%,respectively.Conclusion Although different population groups in Rizhao city have relatively high awareness of HIV/AIDS,there still exist some deficiencies,and consequently education and publicity in this respect should be further strengthened.
9.Studies on the Use of "Yangyinshengji", Film as Wound Dressing
Zhi GUO ; Gen MENG ; Yongyi ZHENG
Chinese Traditional and Herbal Drugs 1994;0(02):-
Yangyinshcngji" Film is a modernized wound dressing prepared by incorperating carboxymethyl cellulose into the traditional Chinose powdery prescription for nourishing the "Yiu" and promoting tissue regeneration. When used as dressing in dermabrasivc wound of short-haired albino guinea pigs, in comparison with conventional gauze dressing, it showed no significant differences in preventing wound infection, but is more effective in reducing wound exudation or enhancing wound healing (P
10.Surgical approach for sigmoid sinus diverticulum which caused pulsatile tinnitus.
Zhao-li MENG ; Yu ZHAO ; Yun ZHENG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2010;45(6):511-512
Cranial Sinuses
;
surgery
;
Diverticulum
;
complications
;
surgery
;
Humans
;
Male
;
Middle Aged
;
Tinnitus
;
etiology
;
surgery