China ; Humans ; Periodontics ; trends

Dental Scaling ; Dentistry ; manpower ; General Practice, Dental ; manpower ; Health Education, Dental ; manpower ; Humans ; Oral Hygiene ; Outcome Assessment (Health Care) ; Periodontitis ; therapy ; Toothbrushing

Aggressive Periodontitis ; diagnosis ; therapy ; Humans

Dental Implantation, Endosseous ; Dental Implants ; Dental Restoration Failure ; Humans ; Prognosis

Volatile oil components and the contents and types of amino acid in spica of Prunella vulgaris were analysed by GC-MS and amino acid analyzer. Esters, fatty acids, aromatic hydrocarbon, ketone and several alcohol compounds were identified by mass spectrum comparison. In these ingredients, beta-ionone smelled aroma of cedar, raspberry, nerolidol showed weak sweet soft orange blossom flavor, neroli tasted sweet and fresh, nerolidol tasted sweet with light aroma of wood, hexadecanal showed a weak aroma of flowers and wax, alpha-sinensal had rich and fresh sweet orange flavor. To some extent, these types of aromatic substances can affect the taste of herbal tea or decoction made of Spica Prunellae. Among amino acids detected, natural amino acids accounted for a larger proportion, and those natural amino acids showed bitterness, slight bitterness, sourness (freshness), sweetness, slight sweetness, sourness (slight freshness). The results indicated that bitter and slightly bitter amino acids have the greatest impacts on the sense of Spica Prunellae.
Amino Acids ; analysis ; Gas Chromatography-Mass Spectrometry ; Oils, Volatile ; analysis ; Prunella ; chemistry ; Taste

Acute Disease ; Animals ; Behavior, Animal ; drug effects ; Female ; Male ; Mice ; Mice, Inbred ICR ; Nitriles ; poisoning ; Rabbits

OBJECTIVETo observe root surfaces and analyze the mineral contents in cementum of patients with rapidly progressive periodontitis (RPP).

METHODSTen teeth were selected from RPP patients, adult periodontitis (AP) patients and healthy (H) control subjects respectively, and prepared for scanning electron microscopy (JSM-35C). The energy-dispersive X-ray analysis was used to measure the mineral contents in cementum (Ca, P, Mg).

RESULTSThe root surfaces of RPP teeth were similar to that of AP teeth. Ca: 64.60% +/- 2.29% vs 63.54% +/- 2.97%, P > 0.05; P: 32.54% +/- 1.29% vs 32.97% +/- 2.40%, P > 0.05; Mg: 2.86% +/- 1.29% vs 3.48% +/- 1.02%, P > 0.05; Ca/P: 2.00 +/- 0.17 vs 1.95 +/- 0.25, P > 0.05. There were no differences in Ca, P, Mg contents and Ca/P ratio between RPP teeth and AP teeth.

CONCLUSIONThere may not be cementoplasia in a part of RPP teeth.

Adult ; Dental Cementum ; chemistry ; ultrastructure ; Humans ; Microscopy, Electron, Scanning ; Periodontitis ; pathology ; Tooth Root ; chemistry ; ultrastructure

Objective To investigate the change of secretory leukocyte protease inhibitor (SLPI) and elastase(EA) in the different stages of periodontal inflammation and to evaluate the possibility of the two proteins as saliva markers reflecting overall periodontal health status.Methods Unstimulated whole saliva were collected from 86 subjects (divided into 4 groups as healthy,gingivitis,moderate periodontitis and severe periodontitis).Fifteen patients with moderate or severe periodontitis were only given scaling and root planning(SRP).Whole saliva was collected and clinical patameters were recorded at baseline and four weeks after the treatment.SLPI concentrations were determined with enzyme linked immunosorbent assay (ELISA) systems,while EA with low-molecular-weight substrate reaction.Results There were no statistical differences of SLPI concentrations among four groups ( P ＞ 0.05 ).However,EA activities in moderate periodontitis and severe periodontitis groups [ 0.077 (0.060) and 0.077 (0.489 ) ] were higher than in healthy and gingivitis group [0.058(0.028) and 0.058 (0.024) ] (P ＜0.05).SLPI only showed a weak negative correlation with age ( r =- 0.301,P ＜ 0.05 ),rather than with EA or clinical parameters.In 15 patients with chronic periodontitis the mean concentration of SLPI and EA activity was 2.031 (2.449 ) μg/L and 0.075 ( 0.118 ),and both decreased significantly to 1.405 ( 0.659 ) μg/L and 0.055 (0.028) respectively 4 weeks after SRP.Conclusions After SRP,the decrease of SLPI concentration and EA activity in saliva may reflect the periodontal inflammation subsiding.SLPI in saliva was not correlated with the development of periodontal inflammation.

OBJECTIVETo investigate the periodontal status of the family members of type 2 diabetes mellitus.

METHODSA total of 167 subjects in 43 families of type 2 diabetes were enrolled in this study (71 male, 96 female; mean age: 49.2). Periodontal index including probing depth (PD), plaque index (PLI), bleeding index (BI), attachment loss (AL) and the numbers of tooth loss were recorded.

RESULTSNinety-seven diabetic patients all have periodontitis, 50 mild, 24 moderate and 23 severe periodontitis. Of 48 non-diabetic patients, there are 5 gingivitis, 30 mild, 11 moderate and 2 severe periodontitis. There is statistically significant difference in the incidence of gingivitis mild moderate and severe periodontitis between diabetic and non-diabetic patients (chi(2) = 17.96, P < 0.05). The periodontal index PD, AL and numbers of tooth loss in diabetes family members were significantly higher than those of non-diabetes family members (P < 0.05). The clinical parameters were not different between well-controlled family member and non-diabetes family member.

CONCLUSIONSPeriodontal destruction of diabetes members was more severe than that of non-diabetes members. Diabetes mellitus may be a risk factor for periodontitis.

Adolescent ; Adult ; Aged ; Diabetes Mellitus, Type 2 ; complications ; Female ; Gingivitis ; complications ; epidemiology ; Humans ; Male ; Middle Aged ; Periodontal Index ; Periodontitis ; complications ; epidemiology ; Young Adult

OBJECTIVETo evaluate the short term clinical results of scaling and root planning (SRP) only, SRP combined with amoxicillin (AMX) and metronidazole (MTZ) after supragingival scaling or after SRP in the treatment of aggressive periodontitis (AgP).

METHODSA total of 45 patients with AgP were randomly divided into SRP group, SRP with AMX + MTZ after supragingival scaling group and AMX + MTZ after SRP group. Subgingival scaling and root planning were performed one week after supragingival scaling and finished within 1 month. AMX and MTZ were given for 7 days immediately after supragingival scaling or the last time of SPR. Clinical examinations including probing depth (PD), attachment level (AL) and bleeding index (BI) were performed at baseline and 8 weeks after non-surgical periodontal treatment by the same examiner.

RESULTSThere were more PD reduction and AL gain in both AMX + MTZ after supragingival scaling group and AMX + MTZ after SRP group compared with SRP group [2.5 (1.8, 3.3) mm, 2.3 (1.9, 2.7) mm vs. 1.8 (1.3, 2.1) mm, P < 0.05]; [0.9 (0.5, 1.4) mm, 0.8 (0.4, 1.3) mm vs. 0.4 (0.2, 1.0) mm, P < 0.05]. In sites PD ≥ 7 mm, PD reduction was more in AMX + MTZ after supragingival scaling group than AMX + MTZ after SRP group [4.0 (3.0, 5.0) mm vs. 4.0 (3.0, 4.0) mm, P < 0.05)].

CONCLUSIONSThe combined use of AMX and MTZ during non-surgical periodontal treatment for patients with AgP was effective in short term. In patients with most sites PD ≥ 7 mm, AMX and MTZ could be taken after supragingival scaling, but the long-term clinical effects needs further investigation.

Adult ; Aggressive Periodontitis ; drug therapy ; therapy ; Amoxicillin ; therapeutic use ; Anti-Bacterial Agents ; therapeutic use ; Anti-Infective Agents ; therapeutic use ; Combined Modality Therapy ; Dental Scaling ; Drug Therapy, Combination ; Female ; Humans ; Male ; Metronidazole ; therapeutic use ; Root Planing ; Time Factors ; Young Adult