No abstract available.
Melanosis*

Melanosis

No abstract available.
Melanoma* ; Melanosis*

Melanosis ; Vitiligo

Background: Melasma is an acquired hyperpigmentary disorder occurring on sun-exposed areas of the face and neck. There is little information on its prevalence, epidemiology and clinical characteristics in the Philippines. Objective: To determine the prevalence, epidemiology and clinical characteristics of melasma in Philippine dermatology patients. Methods: This was a multicenter, cross-sectional study conducted from July to December 2013. The investigators determined the prevalence of melasma in 12,068 dermatology patients from six government hospitals and private clinics in Metro Manila, Philippines. The melasma patients, aged 18 years and above, were given self-administered questionnaires with topics related to demographic information and medical history. They were also examined by the investigators (dermatologists) to determine the clinical profile of their melasma. Results: Of the 12,068 dermatology patients who were seen at the selected hospitals and private clinics, 153 (1.26%) were clinically diagnosed with melasma. A majority of the melasma patients were Filipinos (73.20%), aged 41-50 years old (37.91%), with an average age of 42.40 + 9.68 years, and Fitzpatrick skin types III and IV (29.41% and 57.52%, respectively). Melasma was more prevalent in females (81.70%), most of whom had prior history of pregnancy (76.8%). Oral contraceptive use was also reported in 37.6% of the female patients from which 63.83% have used it for only 1 year or less. A majority had no coexisting thyroid disease (75.16%) and daily sun exposure was limited to 1 hour or less for most patients (43.14%). Their melasma was mostly malar in distribution (60.13%), epidermal (61.44%), and mild (51.63%) to moderate (27.45%) in severity. The average mMASI score was 4.63 + 3.32. Conclusion The prevalence of melasma was low among Philippine dermatology patients sampled. A majority of the melasma patients were Filipinos, aged 41-50 years old, with Fitzpatrick skin type IV, limited sun exposure, and no coexisting thyroid disease. They were mostly females with a prior history of pregnancy. Their melasma was mostly malar in location, epiderma type, and mild in severity. These descriptive data can serve as baseline information for further studies on melasma in the Philippines.
Melanosis ; Philippines

No abstract available.
Fibroblast Growth Factor 7* ; Humans* ; Hyperpigmentation* ; Keratinocytes* ; Lentigo* ; Melanosis*

No abstract available.
Lasers, Dye* ; Melanosis*

30 patients aged 18-60 years old with melasma localized at the epiderm and epiderm plus mesoderm layer topically treated by 2% hydroquinone preparation within 6 months at the Venero-dermatol Institute were evaluated. Good and very good results reached in 42.5%. The size of lesion minimized by > 10% each months, especially 21% in the 2nd month. Mean size of lesion minimized by 75%. In 11.2% of patients, the size of lesion minimized by 90-100% and 56.3% of patients had got the lesion of 70-89% minimized size.
Therapeutics ; Melanosis ; Hydroquinones

No abstract available.
Melanosis* ; Tranexamic Acid*

No abstract available.
Hypopigmentation* ; Melanins* ; Melanocytes* ; Melanosis*