1.Effect of All-trans-retinoic Acid on the Growth and cAMP Level in Cultured Normal Human Melanocytes Stimulated by a-MSH.
Korean Journal of Dermatology 1999;37(8):1017-1028
No abstract available.
Humans*
;
Melanocytes*
;
Tretinoin*
2.Five Cases of Agminated Lentigines.
Seung Hyun HONG ; Jin Ho HONG ; Hae Jun SONG ; Chil Hwan OH
Korean Journal of Dermatology 1995;33(5):983-987
Agminated lentigines may be defind as a circumscribed grouping of small pigmented macules arranged in a small or large group, often in a segmental pattern, each macule consisting of a lentiginous epidermal proliferation of melanocytes. We report five cases of agminated lentigines in otherwise healthy persons. Histologic exarnination of the pigmented lesion revealed findings consistent with lentigo simplex.
Humans
;
Lentigo*
;
Melanocytes
3.Eczema Confined to Becker's Nevus on the Face: The Behavior of Melanocytes during Inflammation.
Annals of Dermatology 2012;24(1):99-100
No abstract available.
Eczema
;
Inflammation
;
Melanocytes
;
Nevus
4.Early Involvement of Hair Melanocytes Prior to Epidermal Melanocytes in the Progress of Halo Nevus.
Korean Journal of Dermatology 2016;54(2):151-153
No abstract available.
Hair*
;
Melanocytes*
;
Nevus, Halo*
5.Comparison of the human melanocyte culture in phorbol 12-myristate 13-acetate-contained medium and physiologic mitogens-contained medium.
Mu Hyoung LEE ; Ji Ho RYOU ; Bum Jin JUBH
Korean Journal of Dermatology 1999;37(2):168-176
BACKGROUND: The growth of cells is closely related to components in a culture medium. There are many reports about cellular characteristics of melanocytes grown in a PMA-contained medium. However, only a few reports have been studied by using a physiologic mitogens-contained medium. To understand melanocyte in vivo, it is necessary to know the cellular biology of melanocytes grown in a physiologic mitogens-contained medium. OBJECTIVE: To investigate any differences between melanocytes grown in phorbol 12-myristate 13-acetate(PMA)-contained medium and in physiologic mitogens-contained medium. METHOD: We examined morphology, number and melanin contents of cultured human melanocytes grown in a PMA-contained medium and physiologic mitogens-, such as bFGF, ET-1 and a a-MSH contained medium. Result : The results are summarized as follows : 1. There were no significant morphologic differences between cells in PMA-contained medium and in physiologic mitogens-contained medium. 2. The number of melanocytes were significantly more numerous in PMA-contained medium on the 2nd day (p<0.05), but significantly less numerous in the same medium on the 6th day (p<0.05). So, the proliferation rate of melanocytes in PMA-contained medium became lower than in physiologic mitogens-contained medium as time went by. 3. Melanocytes grown in PMA-contained medium had significantly increased melanin contents regardless of the time (p<0.05). Conclusion : The proliferation of melanocytes was better in physiologic mitogens-contained medium, the melanization was higher in melanocytes of PMA-contained medium.
Humans*
;
Melanins
;
Melanocytes*
6.Changes in Melanin and Melanocytes in Mottled Hypopigmentation after Low-Fluence 1,064-nm Q-Switched Nd:YAG Laser Treatment for Melasma.
Yong Hyun JANG ; Ji Youn PARK ; Young Joon PARK ; Hee Young KANG
Annals of Dermatology 2015;27(3):340-342
No abstract available.
Hypopigmentation*
;
Melanins*
;
Melanocytes*
;
Melanosis*
7.Some Becker's Nevus Melanocytes Remain Alive after Treatment with Q-Switched Alexandrite Laser.
Han Jin JUNG ; Sun Young MOON ; Mi Yeung SOHN ; Yong Hyun JANG ; Seok Jong LEE ; Do Won KIM ; Weon Ju LEE
Annals of Dermatology 2017;29(3):352-355
No abstract available.
Lasers, Solid-State*
;
Melanocytes*
;
Nevus*
8.A Case of Eccrine Poroma Containing Melanin Granules.
Gwang Yeol JOH ; Ai Young LEE ; Jai Il YOUN ; Yoo Shin LEE
Korean Journal of Dermatology 1985;23(1):105-108
It has been generally assumed that eccrine poroma ariees from acroayringium, epidermal sweat duct unit. One of the characteriatics of thie structure is abaence of melanocytes and melanin granules among ite cells. Hmvever, a cornplete abeence of melanocytes and melanin granules in eccrine poroma is not invariable and a few reparts of such an occurrenee were presented, We report a case of eccrine poroma on the area below lateral malleolus af left foot. Microscpically melanin granules, confirmed by the use of Fontana Masson stain, were found in some of the tumor cells.
Foot
;
Melanins*
;
Melanocytes
;
Poroma*
;
Sweat
9.Targeting senescent dermal fibroblasts responsible for hyperactive melanocytes in melasma.
Jing WAN ; Zhikai LIAO ; Bingqi DONG ; Shan JIANG ; Tiechi LEI
Chinese Medical Journal 2023;136(13):1563-1565
Humans
;
Melanocytes
;
Melanosis
;
Fibroblasts
;
Skin
10.Effect of Latanoprost on the Cultured Human Uveal Melanocytes.
Journal of the Korean Ophthalmological Society 2001;42(6):893-897
PURPOSE: To investigate the effect of latanoprost on the melanogenesis and endogenous PG release. METHODS: Primarily cultured uveal human melanocytes were exposed to 0.1 micrometer, 1 micrometer, and 10 micrometer of PhXA85 and also co-exposured with 1 micrometer of indomethacine or hydrocortisone, the melanin content of each melanocyte was measured with spectrophotometer after 1 week. RESULTS: After 1 week, the melanin content of each melanocyte was increased with 1 micrometer, 10 micrometer of PhXA85(p<0.05). After co-exposure with indomethacine or hydrocortisone, the amount of increased melanin content was less than that of PhXA85 alone and statistically significant with 10 micrometer of PhXA85(p<0.05). CONCLUSIONS: These results show that PhXA85 stimulates melanogenesis of cultured human uveal mela-nocytes and also suggests the possibility of exogenous PGF2 alpha-induced release of endogenous prostaglandin.
Dinoprost
;
Humans*
;
Hydrocortisone
;
Indomethacin
;
Melanins
;
Melanocytes*