OBJECTIVE To prevent and control hospital cross-infection and hematogenous disease dissemination during oral cavity procedures.METHODS The problems that existed universally in instrument treating processes during oral cavity procedures were taken seriously.The perfect management rules and regulations were established.The instructions of technical operation were carried out strictly.We strengthened own-self occupation protection and implemented the standard prevention isolation principle.We guaranteed oral cavity synthesis method to implement,such as the instrument cleaning,disinfection,and antiseptic quality.RESULTS The hospital infection occurred in the oral cavity procedures could be reduced and avoided fundamentally through implementing infection control measure.The medical safety could be ensured.CONCLUSIONS The personnel standard diagnosing and treating operation of medical care should be established in hospital.The idea of disinfection and isolation asepsis should be enhanced.Own-self occupation protection must be required strictly.It is extremely important to control the infection during the oral cavity procedures.

Tests of effects on life of adult fruit fly of Cordyceps polysaccharides from submerged fermentation products showed that the polysaccharides had the activity against senescence. Some samples had very notable effect among which polysaccharides from AT01 (both intracellular and extracellular) had the best effects.

Objective To compare the sedative effects and pharmacoeconomic profiles of two kinds of combination of dexmedetomidine in traumatic brain injury patients.Methods94 cases of traumatic brain injury from February 2015 to September 2016 were selected and randomly divided into two groups including A group(47 patients) and B group(47 patients).All patients received the same nursing intervention before and after operation.Patients in group A were given right of dexmedetomidine combined with propofol drug therapy, patients in group B were given dexmedetomidine combined with midazolam drug treatment.To maintain the agitation score (SAS) in the standard state of two~four and efficiency of sedation, the mean arterial pressure (map), respiratory rate (RR), heart rate (HR), oxygen saturation (SpO2), arterial carbon dioxide partial pressure (PaCO2), central venous pressure (CVP) Glasgow Coma Score (GCS) and pharmacoeconomic profiles were tested in all patients.ResultsAll patients in two groups achieved the expected sedative effect and analgesia scores.However, A group showed a greater decrease in MAP, RR and HR after sedation as compared to B group.In two groups, there was no significant difference was observed in pulse oxygen saturation (SpO2),partial pressure of carbon dioxide in artery(PaCO2), central venous pressure(CVP)or GCS score before and after sedation.Dexmedetomidine combined with MI of alprazolam treatment phase compared with dexmedetomidine and propofol regimen is more economical, and the difference has statistical significance (P<0.05).ConclusionThe effects of dexmedetomidine combined with propofol and dexmedetomidine combined with midazolam two regimens can achieve good sedative effect.But combined with propofol group compared to midazolam combined with group of respiratory and circulatory system have better inhibitory effect, also in drug economics angle, midazolam midazolam combined with group than that of propofol combined with group is more economical, patients taking lower cost.

Objective To assess the risk factors of pulmonary infection in patients with cerebral hemorrhage,and then to provide references for policy-making.Methods Relative literature of crosssectional or case-control studies about risk factors of pulmonary infection in patients with cerebral hemorrhage was searched by computer in data bases such as CNKI,VIP,CBM,WanFang Data and PubMed from January of 1994 to October 2014.Resluts A total of 22 studies (2 case-control studies and 20 crosssectional studies) were brought into the study.The risk factors' OR and its 95％CI was 2.64(2.10-3.33) for over 60 years of age,2.05(1.56-2.69) for smoking history,3.07(2.24-4.19)for those who have diabetes,3.36 (2.40-4.70) for those who have chronic pulmonary diseases,1.54 (1.16-2.05) for those who have heart diseases,2.38 (1.83-3.08) for those who have a history of stroke,5.07 (3.15-8.16) for disorder of consciousness,2.78(2.36-3.27) for amount of bleeding over 30ml,2.85(2.22-3.66) for deviated from midline,2.58 (1.60-4.17) for breaking into ventricle,2.05(1.67-2.51) for high level of fasting blood sugar respectively,and so on.Conclusions Prophylactic measures can be carried out according to the risk factors of pulmonary infection in patients with cerebral hemorrhage,and then to reduce the incidence rate of pulmonary infection.

ObjectiveTo explore the effect of rehabilitation in open wards on chronic schizophrenic patients.Methods48 chronic schizophrenic patients were shifted to open wards with comprehensive rehabilitational therapy.They were evaluated with Positive And Negative Symptoms Scale(PANSS),Nurse's Observation Scale for Inpatient Evaluation(NOSIE),Social Disability Screening Schedule (SDSS) before and 6 months after the shifting.ResultsThere was significant difference in the total scores, negative symptoms scales score, general psychopathological scales score and response deficient factor score of PANSS, all the factors scores except psychiatric manifestations and depression of NOSIE, and scores of SDSS pre- and post-shifting(P<0.01).ConclusionRehabilitation in open wards can improve the negative symptoms and social function of chronic schizophrenics.

Objective To investigate the expressions of estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER-2) and relationships of these expressions with the clinicopathology in breast cancer patients aged 70 years old and over. Methods The expressions of ER, PR and HER-2 were detected by immunohistochemical staining from 124 elderly breast cancer patients, and the relationships of these expressions with pathological classification, tumor size, lymph node metastasis and TNM stage were analyzed. Results Among 124 patients, the positive expression rate of ER and PR was 75.0% (93/124) and 71.0% (88/124),respectively. They were not associated with pathological classification, tumor size, lymph node metastasis or TNM stage (all P＞0. 05). The positive expression rate of Her-2(+++) and Her-2 (++) was 11.3% (14/124) and 24.2% (30/124), respectively. And the expression of Her-2 was significantly associated with tumor size, lymph node metastasis and TNM stage (P＜0. 05) but not with pathological classification (P＞0. 05). Conclusions The positive expressions of ER and PR are not correlated with the clinicopathology in elderly breast cancer patients. Her-2 overexpression is positively associated with tumor size, lymph node metastasis and TNM stage.

Comparing the definition,classification,quantity,core capacity construction and the supervision mode of Chinese and the United States specialist nurses,there was a gap between them.The training for the specialist nurses in China was at the initial stage.The advanced experience should be learned from America to provide the reference for building the core capacity and supervision mode of the specialist nurses.

OBJECTIVE:To analysis the volatile components in wild strains of Rabdosia rubescensin in Jiyuan area. METH-ODS:Headspace solid phase microextraction (HS-SPME) was conducted to extract the volatile components in 43 wild species of R. rubescens,GC-MS was conducted to identify the components,and peak area normalization method was conducted to calculate the relative content of the components. RESULTS:The variety and relative contents of the volatility components in 43 wild species had obvious differences and the ranges of species number and relative content was from 0 to 11 and from 0 to 84.03% respectively. Caryophyllene,caryophyllene oxide,dihydroactinidiolide,phytone and patchouli alcohol were main components which existed in a variety of different strains of volatile components of R. rubescens,and were mainly composed of terpenes,ketones,alcohols and es-ters. In addition,fatty acids such as palmitic acid,oleic acid and linoleic acid were contained in a few individual varieties. CON-CLUSIONS:The internal quality in 43 wild species of R. rubescens has certain differences.

This study was aimed to assay the antibacterial activity of compounds from Rabdosia rubescens. Disc dif-fusion (K-B method) was used to screen the in vitro antibacterial activity. All kinds of chromatography were used to isolate the chemical constituent and structure was identified by MS and NMR spectroscopy. The results showed that six compounds were isolated and identified as oridonin (1), rosmarinic acid (2), caffeic acid (3), salicylic acid (4), ferulic acid (5), vanillic acid (6). Oridonin had activity against Staphylococcus aureus (SA), Methcillin-resistant Staphylococcus aureus (MRSA), β-lactamase positive Staphylococcus aureus (ESBLs-SA), and showed the highest ac-tivity (MIC is 3.125, 6.25 and 6.25 μg·disc-1, respectively), but was still weaker than that of berberine as positive control (MIC is 0.156 μg·disc-1). Ferulic acid had activity against SA and MRSA (MIC is 50 and 50 μg·disc-1, re-spectively). Salicylic acid had only activity against SA (MIC 50 μg·disc-1). It was concluded that oridonin, ferulic acid and salicylic acid were the main antibacterial activity compounds from R. rubescens.

Objective To study the effect of extended nursing on puerperal melancholia incidence.Methods Two hundred perpetrates received interventions of extended nursing after delivery,including education about puerperal state,turning on hot line and creation of QQ group,follow-ups and supporting from family members.Result The incidence rate of puerperal melancholia since performance of extended nursing was significantly lower than what is after its performance(P<0.01).Conclusions The extended nursing can help perpetrates to receive nursing knowledge,alleviate their anxiety,strengthen the confidence to take care of baby.As the result,it can reduce the incidence of puerperal melancholia.