More and more studies indicate that type 2 diabetes mellitus (T2DM) is an independent risk factor of the cognitive impairment. It is showed that factors such as diabetic vascular complications and inherenrt metabolism impairment, affect the cognitive functions of the diabetics, and poorly controlled blood sugar and insulin resistant may also play a role in it.

Objective To investigate the cognitive impairment of middle-aged patients with type 2 diabetes mellitus(T2DM). Methods Wechsler adult intelligence scale-Chinese revised edition (WATS-RC) was used as the tool to examine the cognitive function of middle-aged patients with T2DM and the healthy controls in 51 cases. The t-test was used to compare the differences in score between patients and the control group. The patients were divided into two groups with or without cognitive dysfunction. The logistic regression analysis was made for all the variables to confirm risk factors for the cognitive dysfunction in diabetes. Results The WAITS-RC scores of digit-symbol coding test and block design test were much lower(P<0.05) in diabetes versus control group. The other tests showed no significant difference. The cognitive function was negatively correlated with HbA_1>c and HOMA-IR by logistic regression analysis. Conclusions For middle-aged patients with type 2 diabetes, their cognitive functions such as learning ability, analysis and comprehensive capabilities are impaired. The cognitive function is closely related with HbA_1c and HOMA-IR.

Objective To differentiate between peri-prosthetic infection and aseptic loosening using quantitative analysis of triphasic bone scintigraphy.Methods Twenty-eight patients (9 males,19 females; mean age 67.5 years,range 49-80 years) with recurrent joint pain after arthroplasty were retrospectively assessed.All patients underwent triphasic bone scintigraphy.ROI of each joint was drawn and the ratios of affected to unaffected side were calculated.The ratios of blood flow phase,blood pool phase,static phase,Creactive protein (CRP) and erythrocyte sedimentation (ESR) were quantitatively analyzed by ROC curve.The final diagnosis was based on microbiological and histological examinations.The optimal cut-off value was chosen based on the ideal sensitivity and specificity.Results Nine patients were diagnosed as septic loosening,17 patients aseptic loosening,1 patient bursitis of hip joint and 1 patient suture reaction.Taking the positive results of blood flow phase or blood pool phase as standard for diagnosing septic loosening,the sensitivity,specificity and accuracy of bone scintigraphy were 7/9,78.9％ (15/19) and 78.6％ (22/28),respectively.The AUC of blood pool phase was 0.942,and the sensitivity and specificity were 8/9 and 78.9％(15/19),respectively,with the optimal cut-off value of 1.40.The AUCs of blood flow ratio and CRP were 0.816 and 0.795,with cut-off values of 1.53 and 1.20,respectively.The AUCs of static phase ratio and ESR were 0.474 and 0.722,respectively,both P＞0.05.Conclusions For the diagnosis of septic loosening,quantitative analysis of triphasic 99Tcm-MDP bone scintigraphy,particularly with the ratio of blood pool phase,is more accurate than qualitative analysis.

Objective To evaluate the curative effect of comprehensive rehabilitative treatment for lumbar intervertebral disc protrusion by using the MRI tests before and after the treatment. Methods Forty patients with lumbar intervertebral disc protrusion were treated by a comprehensive rehabilitative treatment program composed of physical modalities, medications, traction, massage and medical gymnastics, for 30 days. MRI test were performed with all the patients, and comparison of the MRI manifestations before and after the treatment was conducted to evaluate the therapeutic efficacy. Results The clinical effective rate was 82.5%. There was no significant difference between the MRI manifestations, including MRI signal intensity, thickness and degree of the protrusion, anteroposterior and transverse diameter, width of lateral recess, before and after the treatment. Conclusion The comprehensive rehabilitative treatment program used in this study did not significantly decrease the size of lumbar intervertebral disc protrusion, but did relieve or cure the clinical symptoms of the patients.

Objective To evaluate 18 F deoxyglucose positron emission tomography (FDG PET) in the detection of suspicious recurrence in head and neck cancers , as compared with CT/MRI imaging. Methods Thirty seven patients with clinically suspicious recurrences in head and neck cancers underwent FDG PET, with 34 checked with CT/MRI imaging. The final diagnosis of recurrence were proved by pathology or clinical following up. Results FDG PET detected recurrence successfully in 32 of 37(86.5%) patients with 3 false positives and 2 false negatives. The FDG PET sensitivity, specificity and accuracy in defining local recurrence were 91.7%, 76.9%, 86.5%, respectively; and those of CT/MRI were 68.2%, 75.0%, 61.8%, respectively. Conclusion In comparison with CT/MRI, FDG PET possesses a higher accuracy in detecting recurrence in head and neck cancers.

Objective To analyze the risk factors of thyroid nodule (TN) in Harbin City,Heilongjiang Province.Methods From November 2014 to January 2015,residents lived in Nangang,Daoli,Daowai districts and villagers of Xubao Town of Hulan District of Harbin City were selected as research subjects,who lived in the local regions for more than 5 years,a total of 2 650 people were surveyed.Influence factors of TN were surveyed by general survey,clinical examination and thyroid ultrasound examination.Logistic regression analysis was used to analyze relationships between various factors and TN in single factor analysis and multiple factors analysis.Results Excluding 36 cases with thyroid surgery history,the total prevalence of TN was 22.92％ (599/2 614),single factor Logistic regression analysis found that females [odds ratio (OR) =1.597,95％ confidence interval (CI) =1.328-1.919],elderly (OR =3.356,95％CI =2.699-4.173),living in cities and towns (OR =1.677,95％CI =1.391-2.021),obesity (OR =1.245,95％CI =1.036-1.497),history of hypertension (OR =1.766,95％CI =1.414-2.205) were the risk factors of TN.In multiple factors Logistic regression analysis,risk factors from high to low in the order were elderly (OR =3.076,95％CI =2.436-3.884),females (OR =1.819,95％CI =1.493-2.215),living in cities and towns (OR =1.701,95％CI =1.400-2.066),history of diabetes (OR =1.644,95％CI =1.235-2.189),obesity (OR =1.325,95％CI =1.085-1.618).Conclusions The risk factors of TN include living in cities and towns,females,elderly,obesity,history of hypertension or diabetes in Harbin City of Heilongjiang Province.

Objective To explore the current status and influence factors of intraoperative hypothermia nursing intervention .Methods A total of 617 nurses in operation room from 17 hospitals were randomly selected by stratified cluster sampling method .The current status and influence factors of intraoperative hypothermia nursing intervention were analyzed with 6 scales.Results A total of 617 questionnaires were issued , and there were 607 valid questionnaires collected , with 98.4% recovery rate.The scores of cognition status scale , self-efficacy scale , safety culture assessment scale , Maslach Burnout Inventory , management status scale and behavior status scale were (77.02 ±8.40), (59.96 ±7.84), (87.84 ±9.67), (61.05 ±15.68), (38.28 ± 5.97) and (45.97 ±8.66), respectively.The single factor correlation analysis showed that job burnout was only related to behavior status (P<0.05), and there were correlations among all the other factors (P<0.05). The multiple linear regression analysis showed that the cognition status , safety culture, job burnout and management status were influence factors of behavior status of intraoperative hypothermia nursing intervention (P<0.05).Conclusions Besides providing cognitive training and belief intervention , the nursing managers should enhance the humanistic care for nurses in order to improve the implementation of intraoperative hypothermia nursing intervention and nursing service quality .

Objective To evaluate the effects of comprehensive thermal insulation measure for maintaining body temperature during perioperative period of liver transplantation for the late hepatic alveolar echinococcosis, and provide theoretical basis for improving the success rate of the operation. Methods A total of 18 patients undergoing liver transplantation for the late hepatic alveolar echinococcosis received comprehensive thermal insulation measure. The changes of nasopharyngeal and rectal temperature, pH, heart rate and blood pressure were monitored in the whole process of operation to justify the effective. Results After 5 min the new liver reperfusion, the nasopharyngeal and rectal temperature were (35. 78 ± 0. 69) and (35. 97 ± 0. 65)℃, and the value of pH decreased dramatically to (7. 29 ± 0. 08), but the heart rate increased to (100. 58 ± 5. 47) times/min (P<0. 01). The systolic blood pressure were (82. 21 ± 10. 45) and (83. 59 ± 12. 71) mmHg during no liver period and 5 min new liver reperfusion (P<0. 01), but all above indexes became normal after 30 min reperfusion. Conclusions During perioperative period of liver transplantation for the late hepatic alveolar echinococcosis, comprehensive thermal insulation measure can maintain the body temperature and other vital signs and effectively prevent the occurrence of intraoperative hypothermia.

Objective:To explore the mediating effect of medication self-efficacy between perceived social support and compliance behavior in young patients with newly treated pulmonary tuberculosis under the Southern Xinjiang Model.Methods:A cross-sectional survey was conducted in Kashgar Tuberculosis Prevention and Control Institute Hospital and Tuberculosis Specialist Hospital of Hetian from January 2022 to April 2023. A total of 302 young patients with initial treatment of pulmonary tuberculosis in were selected as the research objects by convenience sampling method. The General Information Questionnaire, the Tuberculosis Compliance Behavior Rating Scale, Perceived Social Support Scale and Self-efficacy for Appropriate Medication Use scale were used to investigate, and the correlation analysis and mediating effect analysis were carried out.Results:The total scores of compliance behavior, self-efficacy and perceived social support were (119.09 ± 13.49), (23.48 ± 6.25) and (55.67 ± 11.33) respectively. All dimensions of medication self-efficacy and perceived social support were positively correlated with compliance behavior ( r values were 0.555 - 0.943, all P<0.01), and medication self-efficacy was positively correlated with perceived social support ( r = 0.981, P<0.01). Medication self-efficacy played a partial mediating effect between perceived social support and compliance behavior, accounting for 74.46% of the total effect. Conclusions:The medication self-efficacy of young patients with newly treated pulmonary tuberculosis is the mediating variable between perceived social support and compliance behavior. Medical staff should focus on and carefully evaluate the medication self-efficacy and perceived social support of patients, so as to give supportive intervention in time, so as to change or even reverse the non-compliance behavior and improve the compliance level of patients.

Objective:To explore the status quo and influencing factors of stigma in young patients with newly diagnosed pulmonary tuberculosis.Methods:From September 2021 to February 2022, 313 young patients with newly diagnosed pulmonary tuberculosis who were treated and registered in Kashgar, Xinjiang, were selected by convenience sampling. The General Information Questionnaire, Tuberculosis-related Stigma Scale and Tuberculosis Medication Adherence Scale were used to investigate the patients. Multiple linear regression analysis was used to explore the influencing factors of stigma of young patients with newly diagnosed pulmonary tuberculosis.Results:The total score of stigma of 313 young patients with newly diagnosed pulmonary tuberculosis was (47.84±7.55) . Multiple linear regression analysis showed that gender, education level, clinical symptoms, doctor-patient communication and social support were the influencing factors of the stigma of young patients with newly diagnosed pulmonary tuberculosis ( P<0.05) . Conclusions:Young patients with newly diagnosed tuberculosis in Kashgar, Xinjiang, have a strong stigma. Medical and nursing staff should focus on women and patients with low education, strengthen doctor-patient communication, popularize disease-related knowledge, and actively mobilize their social support.