Objective:To explore the effects of nursing based on health belief model on respiratory function exercise compliance and respiratory function among lung cancer patients.Methods:From September 2017 to August 2018, we selected 84 lung cancer patients planed surgery at the First Affiliated Hospital of Zhengzhou University as subjects by convenience sampling. All of patients were divided into two groups according to admission time, 40 cases in control group (from September 2017 to February 2018) and 44 in experimental group (from March to August 2018) . Control group carried out routine nursing and health education. On the basis of that, experimental group implemented nursing care based on health belief model. Respiratory function of patients between two groups after surgery was compared with the percentage of predicted value of forced expiratory volume in one second shared by forced vital capacity (FEV1%) and percentage of predicted value of forced vital capacity (FVC%) ; respiratory function exercise compliance after surgery was compared with the Breathing Exercise Compliance Questionnaire.Results:One week after surgery, the scores of respiratory function exercise compliance of patients in experimental group and control group were (42.1±8.4) and (36.8±10.2) with a statistical difference ( t=-2.609, P<0.05) ; the FEV1% and FVC% of patients in experimental group were (63.8±12.1) and (57.5±11.3) , higher than those in control group with statistical differences ( t=-2.167, -2.617; P<0.05) . Conclusions:Nursing based on health belief model can improve respiratory function exercise compliance and respiratory function among lung cancer patients, which is worthy of clinical popularization.

Objective:To investigate the clinical features,therapeutic methods,therapeutic efficacy,and prognostic characteristics of older patients with acute myeloid leukemia(AML).Methods:We collected data from 134 older patients with AML treated at Peking University International Hospital between January 2015 and February 2023.White blood cell count,bone marrow primitive cell count,cytogen-etic and molecular characteristics,and European LeukemiaNet(ELN)risk stratification at initial diagnosis were retrospectively ana-lyzed.Patients were assigned into two groups according to treatment plan―high-intensity chemotherapy and low-dose treatment―to determine whether intensive chemotherapy would yield survival benefits during treatment and the factors affecting survival.Results:Among 36 patients treated with high-intensity chemotherapy,22(61.1%)achieved complete response(CR);among 90 treated with low-intensity therapy,46(51.1%)achieved CR;and among 19 treated with azacitidine(AZA)+ venecra(VEN),14(73.7%)achieved CR.Medi-an overall survival(OS)was 15 months for high-intensity chemotherapy and 14.5 months for low-intensity treatment(P=0.226).According to ELN risk stratification,patients in the low,medium,and high risk groups exhibited OS of 18,14,and 9 months,respectively(P=0.009).OS for high-intensity chemotherapy and low-dose therapy was 22 and 15 months in the low-risk group(P=0.745),9 and 15 months in the medium-risk group(P=0.783),and 9 and 8 months in the high-risk group(P=0.739),respectively.Patients in the intensive chemotherapy group(n=36)had an OS of 15 and 17 months(P=0.689)compared with AZA+VEN treatment(n=19).The prognosis of six patients with TP53 mutation was significantly worse than those without the mutation,and the median OS was 2 months and 14 months,respectively(P=0.004).One-and 3-year survival rates for the low-,medium-and high-risk groups were 79%,53%,and 44%,and 41%,20%,and 3%,respectively.Multivariate analysis revealed that high peripheral blood white blood cell count(P=0.034),ELN risk stratification(P=0.002),and complications(P=0.017)were correlated with OS,while treatment intensity,age,sex,and bone marrow primitive cell count were not significantly correlated with OS.Conclusions:High-intensity chemotherapy did not yield a significant survival benefit in older patients with AML;however,this result needs to be confirmed in patients at low risk.Patients with TP53 mutations had a poor prognosis.Multivariate analyses revealed that baseline mo-lecular characteristics,leukocyte count,and comorbidities were more important than treatment intensity in predicting survival among older patients with AML.