1.Analysis of object surface cleanness and relative factors in cardiac surgical ICU
Rong YANG ; Xu QIAO ; Meina HOU
Chinese Journal of Modern Nursing 2015;21(2):144-145
Objective To assess the effect of existing cleaning methods applied in cardiac surgical intensive care unit, analyze potential danger and provide evidence to support clean processes in the future. Methods Each patient′s bed unit was defined as a sample and the frequency of hand-to-bed contact and the extent of patient-to-bed contact were assessed.Totals of 15 monitoring surface on each sheet were taken after sterilization within 24 hours and the Relative Light Units( RLU) of the monitoring surface values were compared with Adenosine Triphosphate ( ATP) bioluminescence techniques.Results RLU values were more than 500 on bedside table surface, bed block, ECG buttons,micro pump surface, pressurized infusion ball surface and crank bed.RLU values were between 250 and 500 on nurses′small table surface, breathing machine buttons, rulers and stethoscope surface.RLU values were less than 250 on treatment plate, footboard, pump lines and vacuum tube surface.Conclusions Hand hygiene plays a significant role in daily life.It is important to strengthen routine hand hygiene publicity and education, and monitoring and supervision can be used as an effective measure to improve the surface cleanliness of objects.
2.The clinical effect of Yaotongning capsule combined with etoricoxib in the treatment of lumbar pain and inflammatory status in elderly patients with lumbar osteoarthritis
Pengfei LI ; Qiang JIAN ; Meina QIAO ; Changgui SUN ; Junfeng GAO
Journal of Pharmaceutical Practice 2020;38(4):368-372
Objective To study the clinical effect of Yaotongning capsule combined with etoricoxib for the pain and inflammation of lumbar vertebrae in elderly patients with lumbar osteoarthritis. Methods 120 elderly patients with lumbar osteoarthritis admitted to our hospital from January 2016 to June 2018 were randomly divided into the control group and the observation group, with 60 patients in each group. Patients in the control group were treated with etoricoxib, while patients in the observation group were treated with etoricoxib plus Yaotongning capsule orally. Both groups received medications for 2 weeks. Spinal pain and quality of life score changes were recorded. The inflammatory cytokines in serum TNF-α, GM-CSF, COX-2 and BMP-2 levels were monitored. The clinical efficacy was compared and drug safety profile was evaluated for two groups. Results The effective rates of the control group and the observation group were 78.33% and 91.67% respectively. The effective rate in the observation group weas significantly higher (P<0.05). After treatment, the VAS score for the patients in the observation group was significantly lower than that in the control group (P<0.05). The SF-36 score in the observation group was significantly increased (P<0.05), and the levels of TNF-α,GM-CSF and COX-2 in the serum were significantly lower than those in the control group (P<0.05), and the levels of BMP-2 were significantly increased (P<0.05). Conclusion Yaotongning capsule combined with etoricoxib in the treatment of senile lumbar osteoarthritis has definite curative effect. It significantly reduced lumbar pain, improved quality of life, inhibited inflammatory reaction, and had a better drug safety profile. The further clinical investigation for the combination therapy is warranted.