1.Diagnostic value of three dynamic contrast-enhanced spiral CT scan in liver abscess
Hanlian JIANG ; Qingrui ZHANG ; Meijun ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2011;18(18):2495-2496
ObjectiveTo explcer spiral CT of the liver abscess performance of three dynamic enhanced scanning and its diagnostic value. MethodsRetrospective analysis of clinical or pathologically confirmed by the 7cases of liver abscess CT, all patients were confirmed by CT scan and hepatic arterial phase, portal phase, balance of three dynamic contrast-enhanced scan, 1 case of delayed 7 minutes and then scan. Results7 cases of a total of 10liver abscess. Three dynamic enhanced MRI signs:6 typical abscess in four cases,showed double loop sign; an abscess had no enhancement phase enhanced the performance of balance on the edge just to clear; an edge enhancement was tumor size sign. 4 cases does not show typical abscess in three petal sign and tumor size sign; a show cluster sign andcontinuing to strengthen the sign, while changing the boundary clear and sharp. 4 of 10 abscesses in the liver parenchyma around the abscess,showed a transient arterial phase hepatic enhancement. ConclusionDynamic contrast-enhanced spiral CT scan three phases of liver abscess, especially in atypical liver abscesses had a higher diagnostic value.
2.Design of Balance Function Telerehabilitation System Based on C/S.
Xiulin XU ; Jiaojiao ZHANG ; Meijun AN ; Jianhui WANG
Journal of Biomedical Engineering 2015;32(2):363-372
This article shows a new design of telerehabilitation system for balance function assessment and training in our laboratory. The system is based on C/S network architecture, and realizes the telecommunication through socket network communication technology. It implements the teletransmission of training data and assessment report of sit-down and stand-up, online communication between doctors and patients, and doctors'management of patient information. This system realizes remote evaluation and telerehabilitation of patients, and brings great convenience for the patients.
Humans
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Physical Therapy Modalities
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Postural Balance
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Rehabilitation
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Telecommunications
3.Isolation and identification of several chemical constituents in sponge Tedania sp.
Lixin ZHANG ; Feng XUE ; Meijun TANG
Chinese Journal of Marine Drugs 1994;0(03):-
Objective To investigate the chemical constituents in sponge Tedania sp..Methods Solvent extraction,gel and silica column chromatography were used to separate the chemical constituents,the structures of whichwere identified by physicochemical properties and spectral analyses.Results Six compounds were isolated and their structures were identified as cholesterol(1),stearic acid(2),?-sitosterol(3),daucosterol(4),4-hydroxybenzoic acid(5)and thymidine(6).Conclusion Compounds 1,2,3,5 were first found from this marine invertebrate.
4.Classic clinical thinking cultivation of treatise on febrile disease teaching course
Meijun LU ; Youtang ZHANG ; Min SUN
International Journal of Traditional Chinese Medicine 2013;35(12):1090-1091
The classic treatise on febrile disease is one of the four great classics of traditional Chinese medicine,is the bridge of TCM theory and clinical courses.We think there are the following three aspects to cultivate the students' clinical thinking through this classic,teaching:the first is case teaching method throughout the class; the second is the application of multiple teaching methods to improve the teaching effect; and the third is the reform of examination way and improving the students' clinical interest.
5.Measurement of health-related quality of life in coronary heart disease: a review.
Meijun Lü ; Huiyong ZHANG ; Zhe ZHANG ; Guanlin YANG
Journal of Integrative Medicine 2011;9(12):1277-85
This paper introduces the development and application of health-related quality of life (HRQOL) scales in research on coronary heart disease (CHD). Currently, the scales for CHD patients have been more systematically developed and widely used in foreign countries, while domestically in China, they are developed successfully but problematically; research in this field has started later and the scales introduced are limited and not suitable for the entire range of domestic CHD patients. Thus, this paper introduces 26 HRQOL scales in research on CHD, including five generic scales, ten disease-specific scales from abroad and eleven scales originating from China. With the deficiency of HRQOL scales, especially that in traditional Chinese medicine and specific scales, this paper analyzes and summarizes the problems existing in development of scales. The authors also provide solutions in order to help the development and application of scales in further studies.
6.Cloning and Sequencing of the Gene Encoding Variant-Specific Surface Antigen from Giardia lamblia
Yajie LI ; Meijun TENG ; Yongzhi LUN ; Da LI ; Yongqing ZHANG
Chinese Journal of Parasitology and Parasitic Diseases 2008;26(3):197-202
Objective To clone and sequence variant-specific surface antigen gene from Giardia lamblia isolate SUCH/89/BTMRI/2(C2) derived from human in China. Methods Total genomic DNA of G.lamblia was extracted and a full-length variant-specific surface antigen gene fragment was amplified by pelymerase chain reaction (PCR). The PCR product was cloned into pMD19-T simple-vector, transformed into an Escherichia coli JM109 strain and then sequenced. The sequence analysis for cloned fragment was finished by Vector NTI 9.0 software for the homology of Giardia variantspecific surface antigen gene to that of sequences publishend in GenBank. Results The full-length variant-specific surface antigen gone fragment from G. lamblia was found to be 2 142 bp, encoding a 713 amino acid polypeptide and contained a single open reading frame (ORF). The deduced polypeptide sequence was rich in cysteine (11.8 mol%), most of which occurred with in 29 copies of the 4-amino acid CXXC motif, one GGCY-tetrapeptide motifs and three NXS consensus N-linked glycosylation sites. This polypeptide was also rich in threonine (10.2 mol%), glycine (12.1 mol%) and alanine (10.1 mol%). Like other previously identified VSPs, it contained a highly conserved hydropbebic Cterminal region. The homology of G. lamblia SUCH/89/BTMRI/2(C2) variant-specific surface antigen gene to that of sequence (TSA417) published in GenBank was 99% both at the nueleotide and the amino acid levels. Conclusion The full length variant-specific surface antigen gene from the isolate of G. lamblia has the common characteristics with other previously identified VSPs.
7.An investigation of foot care behavior in patients with high risk of type 2 diabetic foot and analysis of influencing factors
Jing LI ; Yuehua ZHANG ; Meijun WANG ; Qiuling XING
Chinese Journal of Practical Nursing 2015;31(18):1357-1360
Objective To investigate the level of foot care behavior and analyse related influencing factors in patients with high risk of type 2 diabetic foot (DF).Methods Apply the Chinese version of the Nottingham Assessment of Functional Footcare to 300 cases of patients with high risk of DF and take oneway ANOVA and multiple stepwise linear regression analysis on the general information and current foot condition.Results The score of foot care behavior was (45.58 ±7.83) scores.52.3 percents patients' scores were less than 45.Gender,previous education of diabetic foot care and history of diabetic foot ulcer were influencing factors of foot care behavior in patients with high risk of type 2 diabetic foot (t=3.196,3.392,2.462,P<0.05).Conclusions The current level of foot care behavior was relatively low in patients with high risk of type 2 DF.It was also approved that female patients with high risk of DF who had received diabetic foot care education and suffered from diabetic foot ulcer before score much higher on foot care behavior.
8.The positive experience of family caregivers of diabetic foot:a qualitative study
Yuehua ZHANG ; Qiuling XING ; Jing LI ; Meijun WANG
Chinese Journal of Practical Nursing 2015;(31):2396-2399
Objective Mining and exploring the positive experience of family caregivers of diabetic foot,aims to deepen the conceptual framework of positive aspects of caregiving and to provide a basis for interventions. Methods A qualitative study design was used guided by the conceptual framework of positive aspects of caregiving.Ten family caregivers of patients with diabetic foot were surveyed. The Colaizzi qualitative analysis method and the framework method were used to analysis the qualitative data. Results The caregivers′positive experience was described from 4 aspects:quality of caregiver/care receiver daily relationship, caregiver′s feeling of accomplishment, meaning of the caregiver′s role in daily life and the caregivers′gain. The caregivers′positive experience was influenced by the caregiver′s sense of self-efficacy and the enrichment events in daily life. Conclusions Family caregivers of diabetic foot get positive experiences in caregiving. The conceptual framework of positive aspects of caregiving explains the relationship between caregivers′positive experience and the determine factors, and it will be helpful to the designing and implementing of interventions. The positive experience should be considered when an intervention program will be conducted for supporting family caregivers.
9.Preventive effect of gastrodin on cognitive decline after cardiac surgery with cardiopulmonary bypass: A double-blind, randomized controlled study.
Zhao, ZHANG ; Pu, MA ; Younian, XU ; Meijun, ZHAN ; Yunjian, ZHANG ; Shanglong, YAO ; Shihai, ZHANG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2011;31(1):120-7
Cognitive decline is a common complication after cardiac surgery with cardiopulmonary bypass (CPB), but as such no pharmacological therapy has been shown to be efficacious in preventing the decline. However, gastrodin has been shown to have multi-pharmacological effects on neurological functions. We undertook this study to test the hypothesis that gastrodin would potentially prevent CPB-associated neurocognitive decline. We randomly assigned 200 patients undergoing mitral valve replacement surgery to receive either gastrodin (40 mg/kg) or saline after the induction of anesthesia and subsequently evaluated cognitive function before surgery, at discharge, and at 3rd month after surgery by using a battery of five neurocognitive tests, or adverse effects of gastrodin postoperatively. Neurocognitive decline in postoperative function was defined as a drop of 1 SD or more in the scores on tests of any one of the four domains of cognitive function. Cognitive decline occurred in 9% of the patients in the gastrodin group in contrast to 42% in the control group (P<0.01) at discharge. Cognitive outcome could be determined at 3rd month in 87 patients in the gastrodin group and 89 in the control group. Cognitive decline was detected in 6% in the gastrodin group and 31% in the control group (P<0.01). The incidences of possible adverse effects were similar between two groups. These results indicate that gastrodin is an effective and a safe drug for the prevention of neurocognitive decline in patients undergoing mitral valve replacement surgery with CPB.
10.Preventive Effect of Gastrodin on Cognitive Decline after Cardiac Surgery with Cardiopulmonary Bypass: A Double-Blind, Randomized Controlled Study
ZHANG ZHAO ; MA PU ; XU YOUNIAN ; ZHAN MEIJUN ; Zhang YUNJIAN ; YAO SHANGLONG ; ZHANG SHIHAI
Journal of Huazhong University of Science and Technology (Medical Sciences) 2011;31(1):120-127
Cognitive decline is a common complication after cardiac surgery with cardiopulmonary bypass (CPB),but as such no pharmacological therapy has been shown to be efficacious in preventing the decline.However,gastrodin has been shown to have multi-pharmacological effects on neurological functions.We undertook this study to test the hypothesis that gastrodin would potentially prevent CPB-associated neurocognitive decline.We randomly assigned 200 patients undergoing mitral valve replacement surgery to receive either gastrodin (40 mg/kg) or saline after the induction of anesthesia and subsequently evaluated cognitive function before surgery,at discharge,and at 3rd month after surgery by using a battery of five neurocognitive tests,or adverse effects of gastrodin postoperatively.Neurocognitive decline in postoperative function was defined as a drop of 1 SD or more in the scores on tests of any one of the four domains of cognitive function.Cognitive decline occurred in 9% of the patients in the gastrodin group in contrast to 42% in the control group (P<0.01) at discharge.Cognitive outcome could be determined at 3rd month in 87 patients in the gastrodin group and 89 in the control group.Cognitive decline was detected in 6% in the gastrodin group and 31% in the control group (P<0.01).The incidences of possible adverse effects were similar between two groups.These results indicate that gastrodin is an effective and a safe drug for the prevention of neurocognitive decline in patients undergoing mitral valve replacement surgery with CPB.