1.Classic clinical thinking cultivation of treatise on febrile disease teaching course
Meijun LU ; Youtang ZHANG ; Min SUN
International Journal of Traditional Chinese Medicine 2013;35(12):1090-1091
The classic treatise on febrile disease is one of the four great classics of traditional Chinese medicine,is the bridge of TCM theory and clinical courses.We think there are the following three aspects to cultivate the students' clinical thinking through this classic,teaching:the first is case teaching method throughout the class; the second is the application of multiple teaching methods to improve the teaching effect; and the third is the reform of examination way and improving the students' clinical interest.
2.Expression of resistance-related genes in lung carcinomas tissue and its clinical significance
Meijun LU ; Caicun ZHOU ; Xinghua YI ; Al ET
China Oncology 2001;0(03):-
0.05).The patients with positive P gp and LRP expression responded more poorly to chemotherapy than those with negative P gp and LRP expression ( P
3.Meta-analysis and Trial Sequential Analysis of Therapeutic Efficacy of Compound Xuanju Capsules Combined with Chemical Medicine versus Chemical Medicine Alone in the Treatment of Polycystic Ovarian Syndrome
Yizheng ZHONG ; Jiahua HUANG ; Meijun PAN ; Fan HUANG ; Weipeng SUN ; Lu ZHANG ; Jing LIN ; Jingjing CHEN ; Pengpeng XIE ; Langchi HE ; Wei FAN ; Kaimin GUO
China Pharmacy 2019;30(17):2404-2409
OBJECTIVE: To systematically evaluate the efficacy of Compound xuanju capsules combined with chemical medicine versus chemical medicine alone in the treatment of polycystic ovarian syndrome (PCOS), in order to provide evidence-based medicine guidelines for clinical medication. METHODS: Retrieved from PubMed, Embase, Cochrane library, CBM, VIP, CJFD and Wanfang database from database establishment to Apr. 5, 2019, randomized controlled trials (RCTs) about therapeutic efficacy (total response rate, ovulation rate, pregnancy rate, FSH level, LH level, testosterone level, degree of endometrial thickening) of Compound xuanju capsules combined with chemical medicine (trial group) versus chemical medicine alone (control group) in the treatment of PCOS were collected. After data extraction and quality evaluation of included studies with modified Jadad scale, Meta-analysis was conducted by using STATA 14.0 software. Trial sequential analysis (TSA) was conducted by using TSA 0.9 software. RESULTS: A total of 15 RCTs were included, involving 1 259 patients. The results of Meta-analysis showed that the total response rate [RR=1.27,95%CI(1.13,1.44),P<0.001], ovulation rate [RR=1.18,95%CI(1.03,1.37),P<0.001], pregnancy rate [RR=1.34,95%CI(1.11,1.61),P<0.001], serum hormone level {FSH [SMD=-0.66,95%CI (-0.51, -0.82),P<0.001], 95%CI(-1.76,-1.41),P<0.001], LH [SMD=-1.24,95%CI(-1.39, -1.08),P<0.001], testosterone [SMD=-1.59,95%CI(-1.76,-1.41),P<0.001]} and endometrial thickness [SMD=1.20,95%CI(1.04,1.37),P<0.001] of the trial group were better than those of the control group, with statistical significance. The results of TSA were reliable. CONCLUSIONS: In the treatment of PCOS, Compound xuanju capsules combined with chemical medicine is better than chemical medicine alone in improving total response rate, pregnancy rate, ovulation rate and endometrial thickness, and reducing serum hormone levels.