OBJECTIVE: To compare the trauma of neck dissection on the human body between two-striae incision and traditional "L" shaped incision by serum trauma cytokines. METHODS: Patients with differentiated thyroid carcinoma hospitized from December 2008 to July 2011 were divided into 2 groups according to their own will. The first group 26 patients) had two-striae incision and the second group 32 patients) had traditional "L" shaped incision. The serum level of interleukin(IL)-2, IL-6 and C-reactive protein (CRP) in all patients were examined 1 day before and 1, 3 and 5 days after the surgery. RESULTS: No statistical significance was found between the 2 groups, although level of IL-2 decreased 1 day after the surgery, but recovered to normal 3 days later. The level of IL-6 in both groups increased 1 day after the surgery, began to decrease 3 days after the surgery, and recovered to normal 5 days after the surgery. The level of CRP suggested statistical significance (P<0.05), which increased obviously 1, 3 and 5 days after the surgery. No statistical difference was found before or after the surgery between the 2 groups (P>0.05). After follow-up for 8-40 months, no local recurrence or lymph node metastasis was found. CONCLUSION Compared with the traditional "L" shaped incision, two-striae incision in neck dissection does not increase the serum level of trauma cytokines and trauma to human body after the surgery. Two-striae incision is an ideal surgical approach to differentiated thyroid carcinoma.
Adult ; C-Reactive Protein ; metabolism ; Carcinoma, Papillary ; blood ; surgery ; Cytokines ; blood ; Female ; Humans ; Interleukin-2 ; blood ; Interleukin-6 ; blood ; Male ; Middle Aged ; Neck Dissection ; methods ; Thyroid Neoplasms ; blood ; surgery