Child atopic disease is a global public health problem.Because it can cause various mental health problems, it is getting more and more attention.In recent decades, the prevalence of child atopic diseases is dramatica-lly increasing, and children′s physical and mental health are affected to different degrees.There are several hypotheses about the potential mechanism between atopic diseases and psychological problems.Herein, the psychological and behavioral problems in children with atopic diseases and the associated mechanism will be discussed.Furthermore, it suggests that the professionals should pay more attention to the children′s psychosomatic diseases, and pay more attention to the interactive effect between atopic diseases and mental health problems.It is important for the diagnosis, prevention and intervention of children with the psychosomatic diseases.