Objective To investigate the effect of the complementary matching character teaching model in clinical infectious department nursing teaching and improve the effect of nursing teaching. Methods 164 student nurses in our hospital from June 2010 to May 2011 were selected and they were randomly divided into the experimental group(37 nurses) and the control group(127 nurses). Besides, the experimental group was divided into introverts (60 nurses) and extroverts (70 nurses) according to the 16 personality factor test scale. The traditional nursing teaching mode was adopted in the control group while in the experimental group complementary matching character teaching model was applied, including four groups: outgoing teachers for introverted students, outgoing teachers for outgoing students, introverted teachers for outgoing students and introverted teachers for introverted students. After two months of training, all the nurses were requested to take a closed book examination and the data of the examination scores and the students' evaluation were analyzed as the teaching effect evaluation by using SPSS 19.0 and the counting data by χ2 inspection, the measurement data by single factor analysis of variance and the test level of α=0.05(bilateral). Results The final evalua-tion results of control group and the group of introverted teacher for introverted students are significantly lower than those of other groups ( P<0 . 05 ) . Conclusion The complementary matching character teaching method has more advantages than the traditional one, but the matching of introverted teacher and introverted students should be avoided. The interaction of teachers and students should be given full play to improve the quality of practice nurse teaching.

Objective To know about the students'wills on the reform in the practical teachings.Methods Sample survey and the relevant analysis were made by the grades of students.Results The main factors to influence students'attitude in learning were as the following order:personal interests,the way of teachings,the importance of the content in teachings,the students asking for more cases,information and topic contents as well as the additional practical teachings such as outdoor visits,situational simulation and community survey,with the low evaluation on social practice and internship.Conclusion Reform in practical teachings should be implemented to meet the various needs to develop pragmatic capacity for the students in different grades.

Due to the limit of large number of students,the traditional teaching mode of lecture in morality and politics theory simply emphasizes teaching lectures in theory and basic knowledge,while ignores the connection between theory and practice.This paper holds that only by creating a novel teaching mode which integrates lecture teaching and multiple chains of practice teaching,together with the mechanism guarantee,can an effective teaching be realized.

Objective To explore the effect of cucumber to moisten lips to alleviate xerostomia in patients with gastrointestinal decompression. Methods 180 patients were consecutively recruited at the department of gastric & intestinal surgery of the affiliated hospital of Guilin medical univemity from August 2010 to December 2011,they were randomly divided into the observation group and the control group,80 in each group.The observation group was given cucumber to moisten their lips besides conventional care,and the control group was only given conventional care.Finally we compared the two groups,and display difference between them in comfort degree of oral cavity. Results The comfort degree and oral cavity conditions of the observation group were better than those of the control group. Conclusions Giving cucumber to moisten lips can alleviate xerostomia and improve comfort level in patients with gastrointestinal decompression.

OBJECTIVE: To study the mechanism of Huoxue Qianyang Granule (HXQYG), a traditional Chinese compound medicine, in revising the left ventricular hypertrophy of hypertension. METHODS: Spontaneous hypertension rats (SHR) were randomly divided into seven groups: untreated group, Songling Xuemaikang (SLXMK)-treated group, captopril-treated group, high-, medium- and low-dose HXQYG-treated groups, and normal control group. The systolic blood pressure (SBP) and left ventricular mass index (LVMI) were measured. The content of angiotensin II (Ang II) in left ventricular tissue was determined by radioimmunoassay. The expressions of angiotensin converting enzyme (ACE) protein and mRNA in left ventricular tissue were analyzed separately by immunohistochemical method and RT-PCR. RESULTS: (1) SBP and LVMI were higher in the untreated group than those in the normal control group, and they were lower in the high- and medium-dose HXQYG-treated groups than those in the untreated group, but higher than those in the captopril-treated group, and without significant difference as compared to those in the SLXMK-treated group. (2) The content of Ang II and expressions of ACE protein and mRNA in the left ventricular tissue in the untreated group were higher than those in the normal control group, and they were lower in the HXQYG-treated groups than those in the untreated group, but higher than those in the captopril-treated group, and without significant difference as compared to those in the SLXMK-treated group. CONCLUSION: HXQYG can reverse the left ventricular hypertrophy of SHR, which may be due to decreasing the amount of Ang II and expressions of ACE protein and mRNA in the left ventricular tissue.

Objective To investigate the expression and significance of Syndecan-1 and E-Cadherin proteins in human sporadic colorectal carcinoma(SCC). Methods Immunohistochemical SP method was used to determine the expression of Syndecan-1 and E-Cadherin in 52 cases of SCC and 18 normal colorectal tissues. Results The positive expression rates of Syndecan-1 and E-Cadherin proteins were 65.38%,100% and 61.54%, 100% in SCC and normal colorectal tissues, respectively, the difference of which between SCC and normal colorectal tissues was statistically significant(P

Objective:To investigate the effects of Seroxat on Essential Hypertensive subjects with anxiety and depression and to explore its clinical implications. Methods:After evaluating 77 cases with essential hypertension by SDS and SAS, the subjects with positive results who were followed for 12 weeks from baseline assessments were randomly divided into experimental group (routine treatment and Seroxat) and control group(only routine treatment) and the subjects with negative results were regarded as non-anxiety and non-depression group. The time of the amelioration of symptom , the duration of hospitalization, the drug costs and clinical outcome were compared between 3 groups. The scores of SDS\SAS\QOL were compared within and between the experimental and control group.Results: In experimental groups and non-anxiety and non-depression groups, the time of the amelioration of symptom and the duration of hospitalization were shorter, the drug costs were less and clinical outcome was significantly better than those of control group. The scores of SDS and SAS in experimental groups were significantly lower and the scores of 3 items of QOL were significantly higher than those of control groups.Conclusion:The drug therapy on anxiety and depression could shorter the time of the amelioration of symptom, the duration of hospitalization, decrease the drug costs in hospital, significantly improve clinical outcome, and also lower the degree of psychological obstacle, improve quality of life of essential hypertension patients.

Objective To explore the influence of levothyroxine(L-T4) in the treatment of primary hypothyroidism on myocardial enzymes and lipids.Methods 78 patients with primary hypothyroidism were selected and treated with L-T4 for 12 weeks.The fasting serum levels promote thyroid hormone(TSH),free T3 (FT3),free T4 (FT4),total cholesterol (TC),triglycerides (TG),low-density lipoprotein cholesterol (LDL-C),aspartate aminotransferase enzyme (AST),creatine kinase (CK) and its isoenzyme (CK-MB),lactate dehydrogenase(LDH) were monitored and analyzed before and after treatment.Results After L-T4 treatment for 12 weeks,compared with before treatment,TSH,TC,TG,LDL-C,CK,CK-MB,LDH,AST were significantly decreased or restored (t =10.5223,26.8498,22.7699,16.2735,22.9329,13.1910,32.0907,22.9597,all P ＜ 0.01).The FT3 was negatively correlated with TG (r =-0.3782),LDL-C(r =-0.3506),AST(r =-0.2843),LDH(r =-0.2974),CK(r =-0.3726) (all P ＜ 0.01)and CK-MB(r =-0.2559) (P ＜ 0.05).FT4 was negatively correlated with TC (r =-0.2660),TG (r =-0.4661),LDL-C(r=-0.5119),LDH(r=-0.5936),CK(r=-0.4877),CK-MB(r=-0.5463) (all P＜0.01)and AST(r =-0.2328) (P ＜0.05).TSH was positively correlated with TC(r =0.5341),TG(r =0.7567),LDL-C(r =0.8240),AST (r =0.3923),LDH (r =0.8073),CK (r =0.9661),CK-MB (r =0.7336) (all P ＜0.01).TSH had,the best correlationship with CK (r =0.9661).Conclusion L-T4 can significantly improve the thyroid function and reduce the blood lipids,myocardial enzymes levels of patients with primary hypothyroidism.

Objective To investigate the expression of HMGB1 mRNA in endometrial carcinoma and its correlation with clinicopathological features of endometrial carcinoma. Methods Semi-quantitative RT-PCR method was used to detect the expression level of HMGB1 gene in 56 cases of endometrial carcinoma and 20 cases of normal endometrium. Results The expression of HMGB1 mRNA in endometrial carcinoma (0. 3512 ± 0. 0985 ) was significantly higher than that in normal endometrium (0. 2208 ± 0. 0170 ).There was a significant difference in the two groups( P ＜0. 05 ). Grouping by clinicopathological features,the expression of HMGB 1 mRNA in endometrial carcinoma had a correlation with clinical-surgical stage ( P＜0. 05), metastasis of lymph nodes ( P ＜ 0. 05), and depth of myometrial invasion ( P ＜ 0. 05 ). Conclusion The high level of HMGB1 mRNA indicated that HMGB1 might play an essential role in the genesis, growth, invasion and metastasis of endometrial carcinoma.

BACKGROUND: The formation of long-term memory includes acquisition, consolidation and reconsolidation. Reconsolidation is very important for the new memory transforming into stable memory. Stress is an important environmental factor in the process of learning and memory. Corticosterone is very important for stress response. At present, research about the impact of corticosterone on reconsolidation of novel object recognition memory is less. Thus, it is very important to test the impact of corticosterone on reconsolidation of novel object recognition memory in rats.
OBJECTIVE: To analyze the effects of corticosterone on the reconsolidation of novel object recognition memory in rats.
METHODS: (1) The rats were intraperitoneal y injected with corticosterone (0.1, 1 and 3 mg/kg) immediately after reactivation. The discrimination index was used to assess memory performance and calculated as the difference in time exploring the novel and familiar objects. (2) The rats were intraperitoneal y injected with corticosterone (3 mg/kg) 6 hours after reactivation. The discrimination index was used to assess memory performance and calculated as the difference in time exploring the novel and familiar objects. (3) The rats were intraperitoneal y injected with corticosterone 3 mg/kg without reactivation. The discrimination index was used to assess memory performance and calculated as the difference in time exploring the novel and familiar objects.
RESULTS AND CONCLUSION: Immediate injection of corticosterone 3 mg/kg after reactivation significantly decreased the discrimination index. At 6 hours after reactivation or without reactivation, corticosterone administration did not impact the discrimination index. These results confirmed that corticosterone administration immediately after reactivation impairs the reconsolidation of novel object recognition memory. The damage effect depends on the reactivation experience and the specific time window after reactivation.