2.Application of clinical pathway in treatment of pneumoconiosis with whole lung lavage.
Xiao-Ying HU ; Mei-Lan LIAO ; Yu-Lan ZHANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2009;27(7):442-443
Adult
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Aged
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Bronchoalveolar Lavage
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methods
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Critical Pathways
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Humans
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Male
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Middle Aged
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Pneumoconiosis
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therapy
3.Case of sublingual cavernous hemangioma.
Ying-Chun TENG ; Dong-Dong YU ; Mei LU
Chinese Acupuncture & Moxibustion 2014;34(1):40-40
4.Efficacy of voriconazole for treatment of invasive fungal infections in 87 cases with hematologic malignancies.
Ai-Mei FENG ; Ju-Ying WEI ; Wen-Juan YU
Chinese Journal of Hematology 2011;32(7):473-475
Adult
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Aged
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Aged, 80 and over
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Antifungal Agents
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therapeutic use
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Female
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Hematologic Neoplasms
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drug therapy
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microbiology
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Humans
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Male
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Middle Aged
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Mycoses
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complications
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drug therapy
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Pyrimidines
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therapeutic use
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Treatment Outcome
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Triazoles
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therapeutic use
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Voriconazole
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Young Adult
5.Clinical and Pathological Analysis on 66 Cases of Neonatal Pulmonary Hemorrhage
xue, XIAO ; mei-ying, ZHUO ; you-xiang, ZHANG ; li, YU
Journal of Applied Clinical Pediatrics 1992;0(06):-
Objective To explore the higher dangerous factors,the early clinical performances and its contents of neonatal pulmonary hemorrhage(NPH).Methods The clinical performances,chest radiograms and autoptical pathological materials of 66 cases of newborns who died of NPH at our neonatal department during 1993 to 2003 were reviewed and analyzed.Results The higher dangerous factors of NPH were premature delivery/low birth weight,serious diseases lead to hypoxia and severe infections.The early clinical performances of NPH were the suddenly aggravation of dyspnea and the increasing of moist sounds.The early X-ray performances were lower penetrance of lung fields extensively and well-distributly with path clouds,the intercostals space usually increased.According to the autoptical(patho)-logy,this X-ray perfomance indicated the edema of the pulmonary with small amount of hemorrhage.Conclusion The patients with the higher dangerous factors and the early clinical performances of NPH,must be diagnosed and interfered it as early as possible to reduce the mortality of NPH.
6.The Role of CNQX in the Different Types of Synaptic Release in Mice
Yi YU ; Ying MEI ; Yi RONG ; Xianguang LIN ; Xiaofei YANG
Progress in Modern Biomedicine 2017;17(27):5219-5222
Objective:To explore the role of 6-CYANO-2,3-DIHYDROXY-7-NITROQUIN OXALINE (CNQX) in different types of synapse secretion.Methods:The spontaneous mEPSCs and eEPSCs at different extracellular concentrations of CNQX in cultured cortical or hippocampal neurons were recorded respectively.Results:The half inhibitory concentration (IC50) of CNQX in evoked neurotransmitter release was significantly higher than that of spontaneous release,indicating that the spontaneous neurotransmitter release was more sensitive to CNQX.No apparent difference was observed between cortical and hippocampal cells,suggesting that the blocking effect of CNQX was similar in different brain regions.Conclusion:CNQX might have differential regulating mechanisms between excitatory spontaneous and evoked neurotransmitter release,but without brain regions specificity.
7.Detection of microvesicle miRNA expression in ALL subtypes and analysis of their functional roles.
Wen-Ying, LI ; Xiao-Mei, CHEN ; Wei, XIONG ; Dong-Mei, GUO ; Li, LU ; Hui-Yu, LI
Journal of Huazhong University of Science and Technology (Medical Sciences) 2014;34(5):640-5
Microvesicles (MVs) are the heterogeneous mixtures of vesicles. MVs released by leukemia cells constitute an important part of the leukemia microenvironment. MVs might act as important reservoirs of microRNAs (miRNAs). It is worth evaluating whether MVs possess some unique miRNA contents that are valuable in understanding the pathogenesis. In this study, we investigated the miRNA expression patterns of Nalm-6-derived MVs, Jurkat-derived MVs and normal cell-derived MVs using miRNA microarrays. The potential target genes regulated by differentially expressed miRNAs were also predicted and analyzed. Results demonstrated that 182 miRNAs and 166 miRNAs were differentially expressed in Nalm-6-MVs and Jurkat-MVs, respectively. Many oncogenes, tumor suppressors and signal pathway genes were targeted by these aberrantly expressed miRNAs, which might contribute to the development of B-ALL or T-ALL. Our findings expanded the potential diagnostic markers of ALL and provided useful information for ALL pathogenesis.
8.Morbidity regularity of severe complications of hypertensive disorder complicating pregnancy in clinics
Shu-Mei WAN ; Yan-Hong YU ; Ying-Ying HUANG ; Gui-Dong SU ;
Chinese Journal of Obstetrics and Gynecology 2001;0(08):-
Objective To analyse incidence of the severe complications of hypertensive disorder complicating pregnancy and the influence on the outcome of pregnancy.Methods A retrospective study of 4107 cases among 71 020 cases who delivered in hospitals from 1995 to 2004 in Guangzhou was conducted. Results The morbidity of hypertensive disorder complicating pregnancy was 5.78%,in which the morbidity of severe pre-eclampsia was 27.78% (1141/4107),of mitis pre-eclampsia was 72.22% (2966/4107). Maternal mortality rate was 0.19% (8/4107),and the specific mortality rate was 11.26/100 000.The proportion of severe complications of hypertensive disorder complicating pregnancy from high to low was as follows:placental abruption 1.68% (69/4107),DIC 1.36% (56/4107),hypertensive disorder complicating pregnancy induced cardiopathy(induced cardiopathy) 1.05% (43/4107),renal failure 0.97% (40/4107),cerebrovascular accident 0.58% (24/4107),and hemolysis,elevated liver enzymes and low platelet (HELLP) syndrome 0.51% (21/4107).Mortality caused by severe complications of hypertensive disorder complicating pregnancy were as follows:cerebrovascular accident 17% (4/24),HELLP syndrome 10% (2/21),DIC 5% (3/56) and induced cardiopathy 2% (1/43).The proportion of perinatal mortality from severe complications were as follows:placental abruption 43% (33/77),HELLP syndrome 42% (10/ 24),DIC 34% (22/64),renal failure 25% (11/44),cerebro vascular accident 24% (6/25)and induced cardiopathy 16% (8/49).Conclusions (1) The morbidity of severe complications from high to low are: placental abruption,DIC,induced eardiopathy,renal failure,eerebro vascular accident and HELLP syndrome.(2) The main causes of mortality for gravida and puerperant are:cerebro vascular accident, HELLP syndrome,DIC and induced cardiopathy.(3) The major complications harmful to perinatal newborns are in the order of:placental abruption,HELLP syndrome,DIC,renal failure,eerebro vascular accident and induced cardiopathy.
9.A survey on the standardized treatment of 33 cases of children thalassemia and their family economic burden in Bao'an district, Shenzhen city, 2009
Wei, WANG ; Jian-mei, LI ; Shao-ying, LI ; Rui-ying, WEN ; Yu-li, CHENG ; Hua, ZHOU
Chinese Journal of Endemiology 2011;30(3):332-335
Objective To investigate the standardized treatment of 33 children with thalassemia and their family financial burden registered in Bao'an district, Shenzhen city, and to provide basic information for formulating health policy for the government. Methods In 2009, preliminary investigations on 39 registered families with thalassemia children were conducted by telephone, and a household survey was made to collect treatment and economic status by questionnaire on 33 children. Results Among 33 cases of thalassemia children, 21 cases(63.7%) were severe anemia, 5 cases( 15.1%) in need of care or special care, and 25 cases(75.8%) were difficult or unable to maintain standardized treatment. The average family monthly income and expenditure was (4060 ± 2002) and (4926 ± 2991) yuan, respectively. The average monthly treatment costs were (2665 ± 1872) yuan, and the average debt amounted to (64 600 ± 53 940) yuan. Fifteen families[60.0%(15/25)] would reduce the times of blood transfusions or iron transpirations when they encountered revenue deficiency. Conclusions The heavy economic burdens on families with children thalassemia result in inadequate or interrupted treatment on sick children and affect their survival and quality of life, which should be taken more attention and social care.
10.Bilateral symmetry of corneal topography
Ying LI ; Yu-Mei JIN ; Xiao ZHANG ; Yu-Min SUN ; Hai-Yan LI ;
Ophthalmology in China 1993;0(01):-
Objective To compare the bilateral symmetry characters of corneal topography in patients with different refraction, age and gender.Design Retrospective case series.Participants 1000 eyes of 500 patients who were going to undergo corneal refractive surgery with myopia from 18 to 47 years old.Methods Bilateral corneal topography was obtained using TOMEY Version 3.30.Contact lenses had not been worn for more than a week before the examination,and patients with dry eye or other ocular and systemic diseases were excluded.Main Outcome Measures Symmetry and symmetric rates of corneal topography.Results Bilateral symmetry of loca- tion of the cone apex and refraction:uniform 3.4%;almost symmetry 1.8%;approximately symmetry 79.0%;asymmetry 15.8%.The rates of bilateral symmetry in patients with different refraction:0.05).Conclusions 80% of patients with myopia have bi- lateral symmetric corneal topography patterns.The rates of bilateral symmetry of corneal topography increase with the increase of spher- ical refraction(