1.The effect of renal angioplasty and medical therapy on blood pressure and renal function in asymptomatic ARAS patients with stenosis of 50%~70%—a prospective controlled study
Chinese Journal of Practical Internal Medicine 2001;0(03):-
0.05).Conclusion Renal angioplasty showed a drug-dosage-saving effect on blood pressure and seemed to protect the renal function from deterioration in asymptomatic ARAS patients with stenosis ranged from 50% to 70%.Large-scaled and long-term studies are needed to verify our results.
2.Long term outcome of PTRA and stenting in patients with atherosclerotic renal artery stenosis and predictors analysis
Chinese Journal of Interventional Cardiology 2003;0(05):-
70% were treated with stents.Patients were followed at 1 month and then every 3 to 6 months.Blood pressure and serum creatinine were measured and dosage of antihypertensive drugs were recorded.The Chinese equation was used to calculate estimated GFR.Results The mean follow-up period was 33.8?10.5(24-54) months.(1) Compared with baseline,blood pressure decreased siginificantly at 1 month and gained a further decrease at 24 months(SBP 129.1?12.9 mmHg vs 139.2?17.5 mmHg;DBP 72.6?7.1 mmHg vs 80.6?12.8 mmHg,both P0.05).Renal function was improved in 9.3% and stabilized in 62.9% of patients,and the overall benefit rate was 72.2%.(3) Logistic analysis revealed that male and diabetes were independent risk factors for renal function deterioration(OR=11.1 and 5.88,respectively,both P
3.Epidemiological Investigation of Constitutional Types of TCM in 355 Cases of Tumor
Xiangnong ZHANG ; Xin WANG ; Mei WANG
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(05):-
Objective To explore the distributed regularity of constitutional types of patients who suffered the gastroenteric carcinomas and lung cancer by epidemiological investigation of constitutional types,in order to analyze the characteristics of different kinds of tumor patients.Methods The standardized Constitution in Chinese Medicine Questionnaire(CCMQ) was answered by 355 patients to evaluate the scores of all kinds of constitutional types.The individual constitutional type was distinguished by the top score method,and the distribution rules of constitutional types in different kinds of tumor patients was analyzed.Results Among the tumor patients,the gentleness type accounted for 17.46 percent,eight pathological constitutions accounted for 82.54 percent.The most two types of pathological constitutions in gastroenteric carcinomas patients were Yang-deficiency and Qi-deficiency,which accounted for 23.98 percent and 23.39 percent respectively,while the majority of that in lung cancer patients were Qi-deficiency(42.93%) and Yang-deficiency(15.76%).Conclusion The patients suffering from different kinds of tumor have different constitution characteristics.It is a better idea to integrate the constitution analysis with syndrome differentiation treatment in clinical practice.
4.Effect of angiotensin-converting enzyme inhibitor on renal function in patients with unilateral atherosclerotic renovascular disease
Xin ZHANG ; Mei WANG ; Haiyan WANG
Chinese Journal of Nephrology 2005;0(08):-
0.05], whereas it is significantly decreased in ACEI group[(69.3?14.6)ml?min-1? (1.73 m2)-1 vs (63.5?16.4)ml?min-1?(1.73m2 )-1,P
5.Progression of treatment in locally advanced breast cancer
Xiaomao GUO ; Xin MEI ; Qian ZHANG
China Oncology 2000;0(06):-
Neoadjuvant chemotherapy combined with surgery and/or radiotherapy is the common method in treating locally advanced breast cancer.This article reviewed the progress on the rationales for neoadjuvant chemotherapy,regimens and courses of chemotherapy,the factors relative to the outcome of the treatment and prognoses,advantage and disadvantage of neoadjuvant chemotherapy.The progress in diagnosis,surgery,radiotherapy and endocrine therapy for locally advanced breast cancer are also summarized.
6.Thought imprinting analytic comprehensive therapy in a lowered resistance state
Yan MIN ; Xin ZHANG ; Yan MEI ; Weidong WANG
International Journal of Traditional Chinese Medicine 2011;33(3):217-219
Based on previous therapeutic experience, we introduce one specific technique of analytic comprehensive therapy in a lowered resistance state, belonging to the systematic psychotherapy of SPT. Analytic comprehensive therapy in a lowered resistance state is a specific and practical technique of SPT, which has been gradually standardized and matured with more than two decades of practice and improvement.
7.Design and validation of bone marrow histological scoring system for myelodysplastic syndrome
mei, ZHANG ; xin-xu, DU ; xu-cheng, JIANG
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(09):-
Objective To design a bone marrow histological scoring system for myelodysplastic syndrome(MDS) in order to provide an objective evaluation of clinical diagnosis,disease development and outcome prediction. Methods HE and Gomori staining were used to observe the morphological alterations in 149 bone marrow biopsies.Immunohistochemical staining for MPO,CD235,F8,CD42b,CD61 and CD34 was performed.The scores of distinct morphological changes of MDS were valued. Results The bone marrow histological scoring system for MDS was established and validated.The scoring system comprised 8 distinct histological features of MDS in bone marrow biopsy.When the score was ≥5,there was significant difference between normal bone marrow biopsy and bone marrow biopsy with MDS(P
8.THE STRATEGIES FOR PREVENTING AND TREATING INFECTION OF CYTOMEGALOVIRUS IN BONE MARROW TRANSPLANTATION
Mei ZHANG ; Shaanxi LIU ; Baoyan WANG ; Xin LIU ; Ruibo CAI
Journal of Pharmaceutical Analysis 1999;11(1):45-47
In bone marrow transplantation (BMT), cytomegalovirus (CMV) interstitial pneumonitis (IP) is one of the most dangerous complications, which has been the first important cause to lead the failure of BMT. At present, there is no effective and specific therapy for CMV-IP, therefore how to prevent CMV infection effectively is a top task. From 1991 to 1996, we used comprehensive steps to prevent CMV-IP in BMT, and none of 14 patients developed CMV-IP. The preventing results that we achieved by using the steps were quite satisfied.
9.Sorting of side population cells from breast cancer MCF-7 cell line and its biological characteristics
Xin SUN ; Ping LI ; Mei ZHANG ; Jiao CHEN
Chinese Journal of Primary Medicine and Pharmacy 2012;19(13):1927-1928
Objective To separate the side population cells(SP) from breast cancer MCF-7 cell line,and observe its biological characteristics.Methods Flow cytometry and Hcechst 33342 dye efflux assay were used to isolate SP cells and non-SP cells from the MCF-7 cell line of human breast cancer.Tumorigenicity of the two subpopulations was observed by a soft agar cloning method.Results The results of FACS analysis indicated that (6.5 ± 0.4 ) %of the MCF-7 cells were SP cells;The vitro colony formation rate of SP cells was(38.5 ±9.4)%,and higher than that of non-SP cells ( 8.4 ± 2.6 ) % ( t =5.34,P < 0,05 ).Concluslon The SP cells sorted from MCF-7 cell line enriched tunor stem cells,which exhibited high tumorigenicity.It indicated that SP cells should play a principal role in breast cancer.
10.Study on medication rule of depressive disorder in medical records of Er Xu Ming Yi Lei An
Tao LI ; Yan MEI ; Xin ZHANG ; Weidong WANG
International Journal of Traditional Chinese Medicine 2011;33(7):617-618
Objective To study the origin, position, pathogenesis and differentiation rule of depressive disorder in ancient medical records, Er Xu Ming Yi Lei An. Methods Study medical records in ancient medical books, Ming Yi Lei An, Xu Ming Yi Lei An, Er Xu Ming Yi Lei An. Adopt Excel to establish medical records' database about depressive disorder, and use frequency analysis method to summarize medication rule of Chinese materia medica for treating depressive disorder. Results Six body symptoms referred in medical records are anorexia,lassitude, sweating, abdominal distension, insomnia, and hypochondriac pain, account 53.41% in top ten symptoms;regulating Qi method is the most frequently used treatment; The most frequently use prescriptions in a descending order are Xiaoyaosan, Buzhong Yiqi Tang, Taoren Chengqi Tang, Modified Guipi Tang, Wendan Tang, Liujun Zi Tang, Suanzaoren Tang, et. Most frequently applied medical herbs in a descending order are bupleurum, dried tangerine peel, white peony alba, tumeric root tuber, fossilia ossis mastoid, and Chinese angelica, et. Conclusion There are certain rules in the origin, pathogenesis, diagnosis and prescriptions of depressive disorder in ancient medical records, Er Xu Ming Yi Lei An.