1.Two Medical Cases of SHI Da-zhuo Using Integrated Traditional Chinese and Western Medicine for Left Ventricular Remodeling and Left Atrial Expansion after Acute Myocardial Infarction
Chinese Journal of Information on Traditional Chinese Medicine 2017;24(6):100-102
This article summarized two medical cases of Professor SHI Da-zhuo treating acute myocardial infarction by Yiqi Huoxue Tuodu Shengji TCM therapy on the basis of conventional Western medicine therapy. Comparison of echocardiography before and after treatment showed that Yiqi Huoxue Tuodu Shengji TCM combined with conventional Western medicine therapy could inhibit the expansion of atrium and ventricle, improve the cardiac ejection fraction and improve the cardiac function after acute myocardial infarction, which could provide references for integrated traditional Chinese and Western medicine therapy for acute myocardial infarction.
2.Relationship between tyrosine phosphorylation and protein expression of insulin receptor substrate-1 and insulin resistance in gestational diabetes mellitus
Hong-Mei QU ; Yuan-Hua YE ; Wei PENG ; Ying ZHAN ;
Chinese Journal of Obstetrics and Gynecology 2001;0(04):-
Objective To study the relationship between tyrosine phosphorylation(TP)and protein expression of insulin receptor substrate-1(IRS-1)and insulin resistance in patients with gestational diabetes mellitus(GDM).Methods IRS-1 expression and TP in skeleton muscle tissue were determined by Western blot and immunoprecipitation in women with GDM(GDM group,n=22),normal pregnant women(normal pregnancy group,n=22)and normal nonpregnant women(normal nonpregnant group,n=13).Fasting plasma glucose(FPG)and fasting insulin(FINS)were measured by oxidase assay and immunoradioassay. Results(1)The levels of FPG,FINS,and insulin resistance index were calculated according to homeostasis model assessment [ HOMA-IR;(5.6?0.8)mmol/L,(15.4?5.1)mU/L,and 1.2?0.5 ] in GDM group were significantly higher than those in normal pregnancy group [(4.4+0.5)mmol/L,(10.6 ?3.1)mU/L,and 0.8?0.3;P
3.CD28/B7 costimulating signal and its clinical significance.
Journal of Experimental Hematology 2002;10(3):265-267
It is necessary that the two signals are required in T cells activation. The first signal is specific, which T cell receptor could recognize and bind MHC molecule by antigen-presenting cells. Another one is nonspecific, which results from CD28/B7/CTLA4 molecules on T cells and antigen-presenting cells. The both of signals regulate function of T cells such as the activation, proliferation and secreting cytokines. CTLA4 showed the up-regulation in CD28/B7 costimulatory pathway as a negative signal. The immunosuppression could occur by blocking CD28/B7 pathway. It provided useful method for immunotherapy in the autoimmune diseases and graft-versus-host disease. But then, the activation of CD28/B7 could be valuable for the immune system recognizing and eliminating tumor cells.
Abatacept
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Animals
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Antigen-Presenting Cells
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immunology
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Antigens, CD
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Antigens, Differentiation
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immunology
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B7-1 Antigen
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immunology
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CD28 Antigens
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immunology
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CTLA-4 Antigen
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Humans
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Immunoconjugates
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Signal Transduction
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immunology
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T-Lymphocytes
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immunology
4.Cloning and expression analysis of GGPPS gene from Panax notoginseng.
Dan-dan MIN ; Mei-qiong TANG ; Gang LI ; Xiao-sheng QU ; Jian-hua MIAO
China Journal of Chinese Materia Medica 2015;40(11):2090-2095
According to the transcriptome dataset of Panax notoginseng, the key geranylgeranyl pyrophosphate synthase gene (GGPPS) in terpenoid backbone biosynthesis was selected to be cloned. Using specific primer pairs combining with RACE (rapid amplification of cDNA ends) technique, the full-length cDNA sequence with 1 203 bp, which containing a 1 035 bp open reading frame, was cloned and named as PnGGPPS. The corresponding full-length DNA sequence contained 2 370 bp, consisted of 1 intron and 2 exons. The deduced protein PnGGPPS contained 344 amino acids and shared more than 73% identity with GGPPS from Ricinus communis and Salvia miltiorrhiza. PnGGPPS also had specific Aspartic acid enrichment regions and other conserved domains, which belonged to the Isoprenoid-Biosyn-C1 superfamily. The quantitative real-time PCR showed that PnGGPPS expressed in different tissues of 1, 2, 3 years old root, stem, leaf and 3 years old flower, and the expression level in 3 years old leaf was significant higher than that in other organs, which suggested that it might not only be involved in the regulation of the growth and development, but also be associated with the biosynthesis of chlorophyll and carotenoids, the development of chloroplast, the shade habit and the quality formation of P. notoginseng.
Cloning, Molecular
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Computational Biology
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Geranylgeranyl-Diphosphate Geranylgeranyltransferase
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genetics
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Panax notoginseng
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genetics
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Real-Time Polymerase Chain Reaction
5.Intravascular large B-cell lymphoma: report of a case.
Guo-hua YU ; Gui-mei QU ; Wei-dong YAO ; Zhi-qiang LANG ; Wei WANG
Chinese Journal of Pathology 2009;38(7):488-489
Antigens, CD20
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metabolism
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Antigens, CD34
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metabolism
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Antineoplastic Combined Chemotherapy Protocols
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therapeutic use
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Cyclophosphamide
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therapeutic use
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Diagnosis, Differential
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Doxorubicin
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therapeutic use
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Humans
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Lymphoma, Large B-Cell, Diffuse
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drug therapy
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metabolism
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pathology
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Male
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Melanoma
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metabolism
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pathology
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Middle Aged
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Prednisone
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therapeutic use
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Vascular Neoplasms
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drug therapy
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metabolism
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pathology
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Vincristine
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therapeutic use
6.Microglandular adenosis of breast: report of a case.
Gui-mei QU ; Zhi-qiang LANG ; Wei-dong YAO ; Guo-hua YU ; Wen-fang YU
Chinese Journal of Pathology 2007;36(9):643-644
7.Leiomyosarcoma of breast with skin metastasis: report of a case.
Guo-Hua YU ; Gui-Mei QU ; Wei-Dong YAO ; Zhi-Qiang LANG ; Lei JIANG
Chinese Journal of Pathology 2007;36(12):860-861
Breast Neoplasms
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diagnosis
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pathology
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Female
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Humans
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Leiomyosarcoma
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diagnosis
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pathology
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Middle Aged
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Skin Neoplasms
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pathology
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secondary
8.Renal Bellini's collecting duct carcinoma: report of a case.
Wei WANG ; Guo-hua YU ; Gui-mei QU ; Wei-dong YAO ; Lei JIANG
Chinese Journal of Pathology 2010;39(9):631-631
Carcinoma, Medullary
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pathology
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Carcinoma, Renal Cell
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diagnosis
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metabolism
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pathology
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radiotherapy
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surgery
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Diagnosis, Differential
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Humans
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Keratins
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metabolism
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Kidney Neoplasms
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diagnosis
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metabolism
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pathology
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radiotherapy
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surgery
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Neoplasms, Squamous Cell
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pathology
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Nephrectomy
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Radiotherapy, Adjuvant
9.APPLICATION OF TRICKLING FILTERS IN TREATMENT OF WASTEWATER FROM GAS-GENERATING WITH HEAVY OIL
Guo-Qu ZENG ; Mei-Ying XU ; Yong-Hua LUO ; Wen-Juan CAI ; Guo-Ping SUN ;
Microbiology 1992;0(04):-
A research combined trickling filter system and active sludge aeration system was applied in the treatment of industrial wastewater from gas-generating with heavy oil. The wastewater contained both high contents of NH+4-N and mixed hydrocarbons including various PAHs. Its BOD5/COD ratio was less than 0.3 and belongs to recalcitrant, toxic wastewater. The results showed a touch-growth biofilms system was formed on the porous packing material and it played a key role in the decrease of toxicity of the influent. It could also improve the biodegradability of the wastewater.
10.Study on Treatment of Dyeing Wastewater in the Combination Process of ABR and SBR
Guo-Qu ZENG ; Sui-Zhou REN ; Mei-Ying XU ; Ying-Hua CEN ; Guo-Ping SUN ;
Microbiology 1992;0(06):-
A laboratory scale combination process of anaerobic baffled reactor(ABR) with sequencing batch reactor(SBR) for treatment of real dyeing wastewater was studied.The effects of operational conditions were investigated.The results demonstrated that removal rates of COD,colour and aniline were 32%~95%,89%~99% and 50%~98%,respectively,the effluents of COD were 30.0 ~97.1mg/L,colour were 8 ~40 times dilution ratio,concentration of aniline were 0.20 ~0.95 mg/L,which could meet the National Discharge Criteria(GradeⅠ) under the operational conditions of HRTs of 24~36 h,organic loading rates of 0.43 ~2.46 kg COD/(m~(3)?d),the influent pH values of 6.5~8.0,ambient temperatures of 20℃~35℃ at the ABR stage and DOs of 2 mg/L,reaction times of 3~10h,settle times of 2 h at the SBR stage.