1.Intravascular large B-cell lymphoma: report of a case.
Guo-hua YU ; Gui-mei QU ; Wei-dong YAO ; Zhi-qiang LANG ; Wei WANG
Chinese Journal of Pathology 2009;38(7):488-489
Antigens, CD20
;
metabolism
;
Antigens, CD34
;
metabolism
;
Antineoplastic Combined Chemotherapy Protocols
;
therapeutic use
;
Cyclophosphamide
;
therapeutic use
;
Diagnosis, Differential
;
Doxorubicin
;
therapeutic use
;
Humans
;
Lymphoma, Large B-Cell, Diffuse
;
drug therapy
;
metabolism
;
pathology
;
Male
;
Melanoma
;
metabolism
;
pathology
;
Middle Aged
;
Prednisone
;
therapeutic use
;
Vascular Neoplasms
;
drug therapy
;
metabolism
;
pathology
;
Vincristine
;
therapeutic use
2.Multilocular cystic renal cell carcinoma.
Zhi-qiang LANG ; Wei-dong YAO ; Gui-mei QU ; Lei JIANG
Chinese Journal of Pathology 2006;35(9):574-575
Carcinoma, Renal Cell
;
metabolism
;
pathology
;
surgery
;
Cytokines
;
metabolism
;
Diagnosis, Differential
;
Humans
;
Immunohistochemistry
;
Kidney
;
chemistry
;
pathology
;
surgery
;
Kidney Diseases, Cystic
;
metabolism
;
pathology
;
surgery
;
Kidney Neoplasms
;
metabolism
;
pathology
;
surgery
;
Male
;
Middle Aged
;
Mucin-1
;
metabolism
;
Nephrectomy
3.Microglandular adenosis of breast: report of a case.
Gui-mei QU ; Zhi-qiang LANG ; Wei-dong YAO ; Guo-hua YU ; Wen-fang YU
Chinese Journal of Pathology 2007;36(9):643-644
4.Leiomyosarcoma of breast with skin metastasis: report of a case.
Guo-Hua YU ; Gui-Mei QU ; Wei-Dong YAO ; Zhi-Qiang LANG ; Lei JIANG
Chinese Journal of Pathology 2007;36(12):860-861
Breast Neoplasms
;
diagnosis
;
pathology
;
Female
;
Humans
;
Leiomyosarcoma
;
diagnosis
;
pathology
;
Middle Aged
;
Skin Neoplasms
;
pathology
;
secondary
6.Multifocal eccrine angiomatous hamartoma: report of a case.
Gui-Mei QU ; Guo-Hua YU ; Wei-Dong YAO ; Zhi-Qiang LANG ; Wei WANG ; Cheng-Gong DONG
Chinese Journal of Pathology 2008;37(12):853-853
Adult
;
Eccrine Glands
;
pathology
;
Female
;
Hamartoma
;
pathology
;
Humans
;
Sweat Gland Diseases
;
pathology
7.Microadenocarcinoma in the head of the pancreas.
Zhi-qiang LANG ; Gui-mei QU ; Wei-dong YAO ; Lei JIANG
Chinese Medical Journal 2007;120(20):1853-1854
8.Effect of EBV immediate-early protein Zta on the cell cycle of Daudi cells and its mechanisms.
Qing-wei GUO ; Jin-dong GUO ; Xue-mei LIU ; Yun-ze LANG ; Hong-xia ZHANG ; Guo-sheng JIANG
Chinese Journal of Hematology 2012;33(1):47-50
OBJECTIVETo investigate the effect of EBV immediate-early protein Zta on cell cycle of Daudi cells and the involved mechanisms.
METHODSThe expression vector encoding Zta was constructed and electroporated into Daudi cells. Flow cytometric analysis was used to detect the cell cycle, Western blot to the protein levels of p21, Rb and E2F-1.
RESULTSThe vector was constructed successfully, the expression of Zta protein inhibited the proliferation of Daudi cells and promoted cell cycle from G(0)/G(1) phase \[(30.0 ± 3.4)%\] to S phase \[(47.7 ± 1.1)%\]. Meanwhile, Rb expression was significantly downregulated, E2F-1 and p21 expression upregulated by Zta.
CONCLUSIONZta could promote G(0)/G(1) phase to S phase transition in Daudi cells, which might be associated with the reduced expression of Rb and increased expression of E2F-1 and p21 protein.
Cell Cycle ; genetics ; Cell Division ; Cell Line, Tumor ; Cyclin-Dependent Kinase Inhibitor p21 ; metabolism ; E2F1 Transcription Factor ; metabolism ; Genetic Vectors ; Herpesvirus 4, Human ; genetics ; Humans ; Immediate-Early Proteins ; genetics ; Retinoblastoma Protein ; metabolism ; Trans-Activators ; genetics ; Transcriptional Activation ; Viral Proteins ; genetics
9.The crystalline polymorph control and selection of gabapentin with polymer heteronuclei.
Liu YANG ; Min-Liang RU ; Mei-Dong LANG
Acta Pharmaceutica Sinica 2010;45(1):109-113
The pharmaceutical properties, including the physical and chemical properties, and the bioavailability are greatly influenced by their polymorphism. In this paper the polymer heteronuclei were used to produce the gabapentin polymorphs that were characterized by X-ray powder diffraction, FT-IR and DSC. The results indicated that the polymer heteronuclei are an effective method to control and select the gabapentin polymorphism. One new polymorph of gabapentin was found besides all known gabapentin polymorphs.
Amines
;
chemistry
;
Anticonvulsants
;
chemistry
;
Calorimetry, Differential Scanning
;
Crystallization
;
Cyclohexanecarboxylic Acids
;
chemistry
;
Molecular Structure
;
Polymers
;
chemistry
;
Spectroscopy, Fourier Transform Infrared
;
X-Ray Diffraction
;
gamma-Aminobutyric Acid
;
chemistry
10. Developing anautomatic scale to delirium detection based on the electronic medical record system
Yan-li ZHAO ; Ling CHEN ; Dong-mei XIE ; Nan LI ; Lang-li GAO ; Ji-rong YUE
Journal of Medical Postgraduates 2020;33(2):184-187
ObjectiveAt present, there are many bedside tools for delirium, but these manual tools are time-consuming and poor feasible. The aim of this study was to establish a delirium screening scale, automatically extracting keywords from electronic medical records (EMR).MethodsWe selected electronic medical records of 779 elderly hospitalized patients in West China Hospital of Sichuan University from 2015 to 2017. Then, R software was used to automatically extract keywords to form a database undercritical ration, correlation coefficient and different analysis methods. Finally, the Delphi method and Analytic Hierarchy Process Weight were carried out to the construct weight coefficient, so as to form the formal scale.ResultsIn the study, we developed a formal scale consisting of 59 items and 11 dimensions. The score of the scale ranged from 0 to 53.4, with a mean value of 6.64, skewness of 2.6 and kurtosis of 8.2.ConclusionThe delirium screening scale based on the EMR can improve the recognition rate of delirium through intelligent and automatic warning, so as to early diagnosis and timely intervention of delirium.