OBJECTIVE:To observe the synergism and attenuation of Fermented Radix Astragali Powder(FAP)on Cyc-lophosphamide(Cy),a tumor chemotherapeutics,and to explore more economical and effective assistant chemotherapeutics.METHODS:In synergism experiments,the mice tumor models(S180 and H22 solid tumor and H22 ascitic tumor)were used to observe the effects of FAP combined with Cy on tumor control rate and survival time of mice.In attenuation experiments,the effects of FAP against toxic reactions including myelosuppression,atrophy of immune organs,and lesions on renal function induced by high dose of Cy in mice were observed.RESULTS:FAP did enhanced the the antitumor effect of Cy on S180 and H22 solid tumor,lessened Cy-induced toxic reactions such as aleucocytosis,the reduction of the nucleated cells in bone marrow and the weight loss of spleen in mice,meanwhile,it showed protective effect on renal function yet without no significant influence on hepatic function.CONCLUSION:FAP has synergistic and attenuation effects on Cy.

Objective To investigate the state of glucocorticoid(GC) - induced osteoporosis (GIOP) and the current prevention of GIOP in patients with primary glomerulonephritis. Methods Primary glomerulonephritis patients receiving GC therapy were observed and bone mineral density (BMD) in the lumbar spine and the femoral neck were measured. Age, sex, body - mass - index, smoking history, the time and accumulative dose of GC treatment, and the state of osteoporosis prevention were investigated, the factors that influence the BMD were analyzed. Results A total of one hundred and twenty- three patients were included in this study. Among them, osteoporosis and os-teopenia were found in 82 patients (66.7%). Lumbar spine BMD decrease gradually with the increase of the accumulative dose of GC. There were statistical differences in the BMD of lumbar spine in patients with receving GC at the period of less than 1 month compared with other groups( 1-12 months) (P

Purpose To discuss changes of macular choriocapillaris hemodynamics in AMD. Methods Eighty six eyes of 86 patients underwent ICGA,including macular drusen in 15 eyes of 15 patients,exudative AMD in 52 eyes of 52 patients,atrophic AMD in 19 eyes of 19 patients,for the observation of macular choriocapillaris perfusion. Results Choriocapillaris filling phase (CFP) of exudative AMD was obviously longer than that of eyes with normal, atrophic AMD and drusen groups ( P

The extracted human maxillary central incisors were endodontically treated and restored with glass-fiber post. Then they were randomly divided into four groups and tested. Results showed that groups with ferrule more than 2 mm had higher fracture resistence than others.

Objective: To compare the coronal sealing abilities of different post and cement systems through measuring the value of leakage by using dye method. Methods: Fifty human mandibular premolars with single canal were divided into 6 groups randomly. A group: roots sealed by temporary material, B group: roots restored with fiber post adhered with composite resin cement, C group: roots restored with casting metal post and core adhered with composite resin and zinc phosphate cement, D group: positive control, E group: negative control. After finishing preparation and restoration of roots, microleakage was determined by using dye method. Results: The groups restored with any post and core system produced significantly less microleakage than temporary material sealing group(P<0.05). But no differences were detected between two groups bonded with the composite resin cement (P>0.05). Posts adhered with zinc phosphate luting agent produced more leakage than those with composite resin cement(P<0.05). Conclusion: Luting agent can decrease the coronal microleakage. Composite resin cement provides better sealing ability.

Objective To investigate the nursing intervention on the effect of diagnosis and treatment of emergency patients with urolithiasis. Methods 98 patients with urolithiasis in emergency department of our hospital from January 2009 to January 2011 were randomly assigned into the observation group and the control group with 49 cases in each group. The control group received routine care, on this basis the observation group was given systemic nursing intervention. The tolerance, SAS score and satisfaction degree was compared. Results 40 patients in the observation group was well tolerated, accounting for 81.6%, significantly higher than 63.3% of the control group. SAS score and satisfaction degree of the observation group were significantly better than the control group. Conclusions Nursing intervention for emergency patients with urolithiasis can significantly reduce pain, improve the mental state and increase their satisfaction degree, which is worthy of clinical application.

Objective:To explore the relationship between false increase of white blood cell count and fragility of erythrocyte membrane in automatic whole blood count. Methods: The osmosis and incubation osmosis fragility of erythrocyte membrane in controls 1 (Group 1, n =30)and white blood cell count false increase (Group 2, n =30) were detected by the operation rule of the group of clinical examination. Results: Compared with the results of Group 1 frogility of erythrocy to membrane in infectious hepatitis,livercirrhosis and liver cancer were reduced( P

Objective To investigate the optimal mild hypothermia course and cerebral temperature of the neonatal rats after hypoxic-ischemic brain injury. Methods The posthypoxic-ischemic rats of experimental group (n=60) were placed in the glass jars immeresd in water bath held constaut at either 29 C or 3l C for 24h, 48h or 72h. While the rats of room temperature group (n=22) were stayed in room air. Blood glucose, blood gases and neuropathology findings were studied to determine the therapeutic effects. Results The brain temperature droped 3C or 5C when enviro ment temperature was 31C or 29C respectively. The blood glucose remained normal. Neuropathology findings reveled that the brain damage of experimental rats reduced 46%～86% compared to the room temperature group. Conclusion Reducing the cerebral temperature by 4～5 C for 72 hours after hypoxic-ischemic brain injury can lead to superior protective effect.

Objective To discuss the image of indocyanine green angiography (ICGA) about high myopia. Methods Tweenty seven patients (54 eyes) with high myopia underwent ocular examination, fundus color photography, simultaneous ICGA and fluorescein angiography (FFA) with the confocal scanning laser ophthalmoscope.The findings for the two modes of amgiographies were compared. Results Lacquer crack was evident on ICGA in 19 eyes among which the focal, plaque choroidal neovascularization (CNV) were apparent in the middle part of lacquer cracks in 10 eyes (52.6%) .In comparison the lacquer cracks were seen in only 7 eyes on FFA. Choroidal capillary atrophy was seen on ICGA and FFA in 14 eyes and ICGA shew thick choroidal vessels in 3 eyes. Conclusion ICGA is superior to FFA for showing choroidoretinal degeneration and atrophy,lacquer crack and CNV in high myopic eyes, and conduce to evaluating prognosis.