1.Research Progress on Insect-resistant Genes From Plants
Hong-Mei CHEN ; Kun-Zhi LI ; Li-Mei CHEN ;
China Biotechnology 2006;0(11):-
Plant insect-resistantgenetic engineering hasopened a new way to prevent and cure against the insect pest incrop and wood productions. With the progresses instudies, many insect-resistantgeneswere cloned and characterized. The classification of most insect-resistantgenes from plant, the functionalmechanism and the applications of theplantinsect-resistantgenes, the problems and prospectsforusing the plant insect-resistant genes in genetic engineering was described.
2.Analysis of surveillance on iodized salt in Baotou during 2008-2010
Zhi-hong, LIU ; Xue-mei, DU ; Dong-mei, ZHAO
Chinese Journal of Endemiology 2011;30(2):179-180
Objective To find out the consumption situation of iodized salt in Baotou, identify problems and take appropriate intervention measures, and to provide scientific basis for further consolidating the results of control measures, strengthening and improving the sustainable elimination of iodine deficiency disorders. Methods Three batches of each quarter, 54 salt samples were sampled in Donghe wholesale division and Qingkun wholesale division in Baotou city salt company during 2008 - 2010; each place of Damaoqi, Baiyun district, and Qingshan district were divided into five sampling areas according to the direction of east, west, south, north, and central position, one school was selected in each district, 30 students aged 8 to 10 from each school were selected, and home salt samples were taken, and salt iodine was tested by direct titration(GB/T 13025.7-1999). Results Qualified rate of wholesale iodized salt was 100%(378/378) during 2008 - 2010, and mean salt iodine was 30.4 mg/kg;qualified rate of household iodized salt was 99.8%(2417/2421 ), and mean salt iodine was 30.4 mg/kg; iodized salt coverage rate was 99.6% (2421/2430) and consumption rate of qualified iodized salt was 99.4% (2417/2430).Conclusions Qualified rate of iodized salt, coverage rate of qualified iodized salt and consumption rate of qualified iodized salt are 90% or more, which has reached the standard of sustainable elimination of iodine deficiency disorders.
4.Myogenic sarcoma of pulmonary vein: report of a case.
Tao ZHU ; Zhi-nong JIANG ; Mei JIN
Chinese Journal of Pathology 2011;40(5):346-347
Adult
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Desmin
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metabolism
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Diagnosis, Differential
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Female
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Heart Neoplasms
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pathology
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Humans
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Myxoma
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pathology
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Ovarian Neoplasms
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secondary
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surgery
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Pulmonary Veins
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Sarcoma
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diagnostic imaging
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metabolism
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pathology
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secondary
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surgery
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Tomography, X-Ray Computed
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Vascular Neoplasms
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diagnostic imaging
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metabolism
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pathology
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surgery
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Vimentin
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metabolism
6.Extracorporeal shock wave therapy for chronic pelvic pain syndrome: an update.
Qi GUO ; Mei HONG ; Zhi-Ping WANG
National Journal of Andrology 2014;20(8):747-750
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common disease in males, which is characterized by persistent discomfort or pain in the pelvic region. As currently used drug therapies fail to produce satisfactory results, it is an urgent task to find new and effective methods for the treatment of CP/CPPS. In recent years, many reports are seen on the extracorporeal shock wave therapy (ESWT) for CP/CPPS. ESWT can significantly improve the symptoms of pelvic pain and urination disorders in CPPS patients, and its therapeutic effect is attributed to the improvement of angiogenesis and block of pain nerves.
Chronic Pain
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therapy
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High-Energy Shock Waves
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therapeutic use
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Humans
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Male
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Pelvic Pain
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therapy
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Prostatitis
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therapy
7.A novel chromene with anti-tumor activities from fungus Phomopsis sp.
Zhi-jun YANG ; Yu YIN ; Mei GE
China Journal of Chinese Materia Medica 2015;40(4):667-671
A new chromene (1) and six known compounds identified as 6-hydroxymellein (2), 6-hydroxy-5-methylmellein (3) nectriapyrone (4), chermesinone A(5), chermesinone B(6), and pomopxanthone A(7), were isolated in our investigation of the cytotoxic constituents from the fermented rice substrate of endophytic fungus Phomopsis sp. HCCB03519. The structures of these com pounds were elucidated through spectroscopic data analysis. All compounds exhibited inhibitory activities against cancer cell lines. Compound 7 showed stronger inhibition against cancer cells than the positive control 5-Fu.
Antineoplastic Agents
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chemistry
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pharmacology
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Ascomycota
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chemistry
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Benzopyrans
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chemistry
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pharmacology
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Cell Line, Tumor
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Fluorouracil
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chemistry
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pharmacology
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Humans
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Isocoumarins
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chemistry
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pharmacology
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Molecular Structure
8.Biodistribution of 99 Tcm O-labeled MAG3-2-nitroimidazole hypoxia imaging agents with different spacers in S180 scarcoma-bearing mice
Lei MEI ; Zhi YANG ; Taiwei CHU
Chinese Journal of Nuclear Medicine and Molecular Imaging 2017;37(1):25-30
Objective To evaluate the hypoxia selectivity of 99 Tcm O?labeld MAG3?nitroimidazole complexes with different spacers. Methods Four kinds of 99 Tcm O?labeled MAG3?2?nitroimidazole hypoxia imaging agents with different spacers were synthesized and radiolabeled. The stability and lipid solubility of BzMAG3?2NIEA(1), BzMAG3?2NIPA(2), BzMAG3?2NIHA(3) and BzMAG3?2NIUA(4) were measured. The uptake was investigated by biodistribution experiment using S180?bearing mice. Two?sample t test was used for statistical analysis. Results All 4 99 Tcm O?MAG3 complexes were stable and negatively charged, showing an increasing trend in fat solubility with the increase of spacer length. In biodistribution study, tumor uptake of 99TcmO?1 and 99TcmO?2 with medium? and short?carbon chain were (0.67±0.18) and (0?65±0.18) %ID/g 2 h post injection, which were (0.19±0.03) and (0.39±0.05) %ID/g for 99TcmO?3 and 99TcmO?4 with long?carbon chain (t=2.78-5.88, all P<0.05). Conclusion Molecular structure of spacers has a significant effect on the physicochemical properties and tumor targeting of 99 Tcm O?labeled MAG3?2?nitroimidazole hypoxia imaging agents, such that the medium?and short?carbon chain spacers show the best hypoxia?selective property.
10.Clinical observation of diclofenac sodium eye drops for postoperative recurrence of pterygium
Zhi-Rong, XU ; Hao, YAN ; Mei, FENG
International Eye Science 2014;(9):1712-1714
To observe the clinical efficacy of diclofenac sodium eye drops for postoperative recurrence of pterygium, and to provide safer drug regimens to prevent the recurrence of pterygium.
● METHODS: From November 2011 to September 2013, 124 patients 134 eyes who underwent surgery because of pterygium in our hospital were randomly divided into trial group ( diclofenac sodium eye drops and sodium hyaluronate eye drops) and control group ( tobramycin dexamethasone eye drops and sodium hyaluronate eye drops), all patients were followed up for 3mo ( once a week ) and the cornea, intraocular pressure and recurrence of pterygium were observed and compared between the two groups.
●RESULTS: Followed up for 3mo, 43 cases (45 eyes) in the trial group and 38 cases (39 eyes) in the control group had done the follow up as planned, in which 14 cases (15 eyes) showed the signs of recurrence, 2 cases (3 eyes) recurred eventually in the trial group, and in the meantime there were 12 cases (13 eyes) with signs of recurrence and 2 cases ( 2 eyes ) with a recurrence eventually in the control group, but no statistical difference was found between the two groups (P>0. 05);there were 6 cases (9 eyes) dropped out of the study with a higher intraocular pressure in the control group, compared to trial group (0 cases of 0 eye), the difference was statistically significant ( P < 0. 05); cornea conditions between the two groups had no statistical significance (P>0. 05).
●CONCLUSlON:Diclofenac sodium eye drops is effective and safe in preventing the recurrence of pterygium.