1.Research on ereythropoietin and its receptor in anemia of neoplasm
Journal of Leukemia & Lymphoma 2008;17(3):231-233
The anemia of chronic disease is chronic infection, inflammation, a class of cancer-related anemia syndrome, anemia in patients with malignant tumors often. In recent years recombinant human erythropoietin, widely used in clinical treatment of anemia, Especially in cancer-related anemia treatment achieved remarkable results, a blood transfusion to avoid the many adverse effects and improve the patient' s quality of life. A control chemotherapy-induced anemia is an important choice. Therefore, rhEPO on cancer-related anemia treatment mechanism has also become a research hotspot.
2. Hippocampus glioma with temporal lobe epilepsy as the main manifestation: The clinicopathologic properties
Academic Journal of Second Military Medical University 2010;31(1):60-62
Objective: To study the clinicopathologic properties of hippocampus glioma with temporal lobe epilepsy(TLE) as the main manifestation. Methods: The clinical data of 6 patients with TLE and hippocampus masses were retrospectively analyzed. The 6 patients included 2 males and 4 females, with the longest history of epilepsy being 4 years. Results: All the 6 patients were surgically treated and were pathologically confirmed to have gliomas, including one angiocentric glioma( AG), one pilocytic astrocytoma (PA) with mucous degeneration, one astrocytoma, one oligoastrocytomao, one oligodendroglioma and one glioblastoma. Glial fibrillary acidic protein(GFAP) was strongly positive in all cases. Epilepsy disappeared after surgery in 5 cases; one patient had recurrence and received a second operation. Conclusion: Hippocampus gliomas with TLE as the main manifestation are usually low-grade gliomas of various types, and operation can obtain satisfactory prognosis.
3.A preliminary study of the relationship between Sema4A gene expression and Th cytokines in immune thrombocytopenia.
Hu ZHOU ; Hong-mei WANG ; Li MA
Chinese Journal of Hematology 2011;32(9):622-623
Adult
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Cytokines
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metabolism
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Female
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Gene Expression
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Humans
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Interleukin-2
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blood
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Interleukin-4
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blood
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Male
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Semaphorins
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genetics
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metabolism
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T-Lymphocytes, Helper-Inducer
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metabolism
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Thrombocytopenia
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genetics
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metabolism
6.The 6th National Conference on Hematology of Ingrative Traditional Chinese and Western Medicine.
Feng LIU ; Xiao-mei HU ; Rou MA
Chinese Journal of Integrated Traditional and Western Medicine 2003;23(4):319-320
Anemia, Aplastic
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drug therapy
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Animals
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Drugs, Chinese Herbal
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therapeutic use
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Humans
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Leukemia, Myeloid, Acute
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drug therapy
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Medicine, Chinese Traditional
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Phytotherapy
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Precursor Cell Lymphoblastic Leukemia-Lymphoma
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drug therapy
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Purpura, Thrombocytopenic, Idiopathic
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drug therapy
7.Research on practice rights of medical colleges and analysis on the countermeasures
Lingna MA ; Mei YIN ; Dexin MENG
Chinese Journal of Medical Education Research 2012;11(6):569-571
Analysis was conducted and rights concerning teachers,students and patients in practice teaching was defined from the perspectives of medicine,pedagogy,ethnics and law through investigating on reasons leading to problems and conflicts in medical universities' practice right.Effective solutions were proposed from the examination of doctor' s qualification,law and pedagogy.Standardization and legalization of clinical teaching was promoted from the perspective of ethnics.
8.Study for Antiinflammatory and Analgesia on Effective Parts of Meconopsis quintuplinervia Regel
Zhiwang WANG ; Mei GUO ; Jun MA
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(01):-
0.05),but analgesia effect of total alkaloid surpassed total flavonoids distinctively(P
9.Expressions of MMP-2, MMP-7 and TIMP-2 in lung carcinoma and their significance
Tonghua MEI ; Bin LUO ; Yin MA
Journal of Third Military Medical University 2003;0(16):-
Objective To investigate the expressions of matrix metalloproteinase 2 (MMP 2), matrix metalloproteinase 7 (MMP 7), and tissue inhibitor of matalloproteinase 2 (TIMP 2) in lung carcinoma tissue and their significance Methods The expressions of MMP 2, MMP 7, and TIMP 2 in 74 cases of lung carcinoma tissues and 20 cases of peri cancerous normal lung tissues were detected by immunohistochemical method, and the correlation between the expressions of these proteins and the clinicopathological parameters and the prognosis was analyzed Results MMP 2 and MMP 7 expressions in lung carcinoma tissues were significantly higher than those in peri cancerous normal lung tissues ( P 0 05), and the expression of TIMP 2 was significantly lower in lung carcinomas with lymph node metastasis than that in lung carcinomas without lymph node metastasis ( P
10.Parenteral organ injury and Immune status in children with rotavirus enteritis
Chinese Pediatric Emergency Medicine 2010;17(3):217-219
Objective To evaluate the parenteral complications and their risk factors and to study the immune status by detecting immunoglobulin and lymphocyte subsets in children with rotavirus enteritis. Methods Sixty-four children with rotavirus enteritis who were treated in Shengjing Hospital of China Medical University between January 2007 and December 2008(observation group) and 18 healthy chiIdren for health screening at pediatric health care center (normal control group) were reeruimd.Clinical manifestations were collected,stool specimens were detected for rotavirus using ELISA,lymphocyte subsets were detected using flow cytometer,and immunoglobulin.liver enzyme and myocardial enzyme were detected.Results Rotavirus enteritis may be complicated by parenteral complications(liver,myocardium,respiratory and nervous system).The activity of ALT,AST,LDH,CK and CK-mB were higher in observation group than that in normal control group(P<0.05).In observation group,liver injury rate in children younger than 12 months was higher than that in children older than 12 months,and the activity of CK and CK-mB were highcr in severe diarrhea cases[CK(324.5±995.5)U/dl,CK-mB(93.8 4±61.5)U/dl]than that in mild diarrhea cases [CK(252.8±130.4)U/dl,CK.mB(59.6±32.6)U/dl](P<0.05).The level of IgG was lower in observation group[(4.46±1.56)g/L]than that in control group[(5.80±1.67)g/L](P<0.05).Lymphocytes subsets study revealed that the activity of CD4+ in observation group[(29.0±4.18)%]was lower than that in control group[(38.6±3.97)%](P<0.05),the activity of CDl9+ [(38.8±3.94)%]was higher than that in control group[(23.1±7.70)%](P<0.05)and the CD4+/CD8+ ratio was reverse in observafion group.Conclusion Rotavirus enteritis may be complicated by parenteral injuries which get liver,myocardium,respiratory and nervous system involved.Children with rotavirus enteritis Call lead to low immune function.Determination of liver enzyme,myocardial enzyme,immunoglobulin and lymphocyte subsets has important clinical significance to monitoring the change of condition and guiding treatment.