Objective To explore the clinical features,treatment methods and effects of late-stage burned complicated with stress ulcer.Methods The clinical data of 206 burned patients were retrospectively analyzed,and the clinical features,treatment methods and effects of burned patients complicated with stress ulcer were analyzed.Results In 206 patients,there were 42 late-stage burned patients complicated with stress ulcer(20.4％),of which 34 cases were cured(81.0％),8 cases died(19.0％) (3 cases died of stress ulcer bleeding,5 cases died of stress ulcer bleeding complications).Conclusion The probability of late-stage burned complicated with stress ulcer is high and dangerous.For the patients with late-stage burned patients complicated with stress ulcer,early enteral nutrition,gastric mucosal protection,wound sepsis to prevent wound infection,the treatment measures should be effectively put into practice,which will be good for making patients stable,and then the patients can be cured.

Strontium-89(89Sr)therapy has been recognized as an effective method for treating bone metastases. It functions as a calcium analog that binds with collagen matrix produced by the MC3T3-E1 cells during collagen mineralization. 89Sr emits pure β rays which palliate bone pains and reduce the number of new metastasis sites. Response to 89Sr is affected by factors such as the location, size and histological type of lung cancer, the type of metastasis and the duration of treatment, and can be predicted by relief of bone pain, elimination of metastasis, CD4 +/CD8 +, ALP, and others. 89Sr therapy is safe and effective. Repeat administration or combined used with other treatments can improve the therapeutic effect of 89Sr.

Objective :To establish a simple, reproducible brain edema model induced by endotoxin in infant rats and explore the role of intracellular free calcium and calmodulin (CaM). in the development of brain edema. Methods: A total of 45 infant rats were divided randomly into endotoxin treated( n = 36) and control( n = 9) group. The animals were intraperitoneally injected with 10mg/kg of endotoxin or saline respectively. The brain tissue intracelluar free [Ca2 + ] as well as the expression of CaM was detected by fluorescence and protein hybridizaton methods respectively. The tissue water content,Evans Blue content and pathology under electronic microscope were also observed. Results:Brain water and EB content were remarkably increased in endotoxin treated animals compared with those in the control, in which the intracellular free [Ca2+ ] was also significantly increased and the expression of CaM up - regulated. Electron microscopic studies revealed that the blood - brain barrier(BBB)was disrupted with neuronal degeneration,neurogliocyte swelling and necrosis. Conculsion :These results suggest that LPS increases the intracellular free [Ca2+ ] ,and activates the CaM - dependent function via Ca2+ /CaM pathway,which might relate to the increased BBB permeability and brain edema formation.

OBJECTIVE To study the influence of enzyme detergent for improving the quality during the cleaning of medical instruments.METHODS The 360 pieces of contaminated instruments for manually cleaning were divided into two groups with 180 pieces each, one group as test one immersed in Lionser enzyme solution 5 minutes at 1∶200 and another one as control immersed in non-enzymatic detergent 30 minutes at 1∶200.Eventually flush all instruments using free water.RESULTS Significant difference(P

ObjectiveTo observe the effect of Sanfeng Rougan Tang on the type of Ganyang Shangkang essential hypertension.Methods42 essential hypertension patients in type of Ganyang Shangkang Zhen were treated with Sanfeng Rougan Tang. The anti-hypertension medicine remained if the patient had taken. The blood pressure and symptoms of the patients was recorded before and a month after treatment.ResultsAfter treatment, the blood pressure and clinical symptoms of the patients had been significantly improved. The ratio of the blood pressure control was 95.2%, and of the primary symptoms control was 94.4%.ConclusionSanfeng Rougan Tang is effective on the type of Ganyang Shangkang essential hypertension.

ObjectiveTo investigate the effect of psychological intervention on quality of life (QOL) of patients with mammary carcinoma.Methods64 patients with mammary carcinoma were divided into intervention group (n=36) and control group (n=28), and psychological status and QOL of patients of two groups were analyzed after treatment.ResultsThe psychological status and QOL of intervention group was better than that of control group (P<0.05～0.001).ConclusionThe psychological intervention in full stage being in hospital can improve QOL of patients with mammary carcinoma, and it is clinically significant to improve cure rate and survival rate of patients.

Objective To compare the clinical effects of low-temperature plasma ablation combined with adenoidectomy and decolle-ment in the treatment for patients with sleep apnea syndrome.Methods Totally 68 patients with sleep apnea syndrome who underwent elec-tive surgical treatment in our hospital from June 2013 to February 2015 were selected as the study objects.According to the order of treat-ment,the patients were randomly divided into the control group and the observation group,with 34 cases in each group.The control group were treated by routine decollement.The observation group were treated by low-temperature plasma ablation combined with adenoidectomy.After operation,the 2 groups were followed up for 6 months.The improvement effects of different operative methods in clinical symptoms and prog-nosis of patients with sleep apnea syndrome were compared.Results The total effective rate in the observation group (97.06%)was higher than that in the control group (82.35%),and the difference was statistically significant (P <0.05).The postoperative VAS pain grading of the observation group was relatively lower.The normal proportion (50.00%) was significantly higher than that in the control group (11.76%).Patients with moderate and severe pain in the control group accounted for 44.12% and 14.71% respectively,which were signif-icantly higher than those in the observation group(P <0.05).The incidence of postoperative bleeding in the observation group(2.94%)was significantly lower than that in the control group while the incidence of fever was higher than that in the control group (P <0.05).After oper-ation and at the end of the follow-up,OSA-18 score of the observation group decreased significantly and were (46.66 ±7.87)and (33.47 ± 10.59)respectively.The decreased range was greater than those in the control group (P <0.05).Conclusion To adopt low-temperature plasma radiofrequency ablation combined with adenoidectomy in the treatment of patients with sleep apnea syndrome can improve the surgical treatment effect,reduce postoperative pain,reduce the incidence of postoperative bleeding,optimize patients’quality of life and improve the prognosis.

Objective To investigate the nutrition support during stress response period after tumor ex-tirpation in middle-aged and elderly patients with oral and maxillofacial tumors. Methods Sixty patients who had undergone maxillofacial tumor extirpation were randomly divided into nutrition therapy group (n = 35) and control group ( n = 25 ). Patients in nutrition therapy group received enteral nutritional treatment, while patients in control group fed themselves. The nutritional status of the two groups before operations were evaluated with Concise Nutritional Assessment Indicators of human body measurement and biochemistry were used to evaluate the nutritional conditions. The incidence of post-operational complications and recovery time ( from the operation to discharge) were analyzed. Results The weight and arm muscle circumference in the nutrition therapy group significantly decreased after operations (P <0. 05). However, in the control group, all the nutritional indica-tors except the total lymphocyte count were significantly lower than the baseline levels after operations (P < 0. 05 ) ; particularly, of the average body weight decreased by about 6 kg. The incidence of complications in the nutrition therapy group was significantly lower than that in control group (5. 7% vs. 12. 0% , P <0. 05). The recovery time was significantly longer in the control group than that in the nutrition therapy group [ (28. 62± 2.38) vs. (22. 76± 3. 24) d, P < 0. 01 ]. Conclusion The nutritional support during the stress response period can satisfy the demands of high catabolism after maxillofacial tumor extirpation operation in middle-aged and elderly patients.

Objective To explore the curative effects,prognostic factors,and adverse reactions of different treatment modalities of chemotherapy in patients with non-small cell lung cancer (NSCLC).Methods151 NSCLC patients were randomly assigned into 3 groups to undergo concurrent chemoradiotherapy ( n = 43 ) ,sequential chemo-radiotherapy ( n = 49 ) ,or pure chemotherapy (n = 59).The clinical data were analyzed.ResultsThe short-term effective rates of the concurrent and sequential chemo-radiotherapy groups were 81.4% and 73.5% respectively with no significantly difference between them,but both significantly higher than that of the pure chemotherapy group ( 39.0% ,both P ＜ 0.05 ).The mortality of the concurrent cherno-radiation group was 53.5% ,significantly lower than those of the sequential chemo-radiotherapy and pure chemotherapy groups (67.3% and 67.8% respectively,both P ＜0.05).The median survival time of the concurrent chemo-radiotherapy group was 26 months,significantly longer than those of the sequential chemo-radiotherapy and pure chemotherapy groups ( 12 and 11 months respectively,both P ＜ 0.05).The l-year survival rates of the 3 groups were 80.2% ,47.1%,and 45.6%.The 2-year survival rates were 58.2% ,38.5% ,and 24.4% ,and the 3-year survival rates were 32.7% ,27.5% ,and 0,respectively.The white blood cell decrease rates of the grades Ⅲ～Ⅳ of the concurrent chemo-radiotherapy group were significantly higher than those of the other 2 groups (both P ＜0.05 ).There were no significant differences in the rates of radiation esophagitis and radiation pneumonitis between the concurrent and sequential chemo-radiotherapy groups.Age,performance status score,clinical staging,and treatment modality were the 4 influencing factors in the prognosis of NSCLC ( all P ＜ 0.05 ).Conclusion Relatively safe with tolerable adverse reactions,concurrent chemo-radiotherapy is superior to sequential chemo-radiotherapy,particularly to pure chemotherapy,in increase of median survival time and survival rate in treatment of NSCLC.Age,PS,clinical staging and therapy method are independent indicators influencing the prognosis.

Objective To evaluate the long-term prognostic capacity of the SYNTAX score Ⅱ(SxScore Ⅱ) and SYNTAX score (SxScore) in patients undergoing left main percutaneous coronary intervention (LM-PCI). Methods A total of 209 patients undergoing unprotected LM-PCI in the Cardiology Department of the Affiliated Hospital of PAP of Logistic College were prospectively collected. Follow up was carried out by telephone or outpatient or rehospitalization. The clinical endpoint focused on MACCE after PCI including composite death, nonfatal myocardial infarction, target vessel revascularization and stroke. The secondary endpoint included cardiac death and stent thrombosis. The SxScore and SxScoreⅡ were retrospectively calculated according to results of coronary angiography and clinical features of patients. Patients were stratified according to tertiles of low (≤22), intermediate (23-32), and high (≥33). The clinical data were comparedbetween three groups. The predictive ability of two scoring systems to MACCE after PCI was compared by COX regression evaluation. Results In 209 patients, 12 patients were lost to follow-up (5.7%), and the median follow-up was 30.2 months, 56 cases (28.4%) were observed to suffer from MACCE. The incidence rates of MACCE were 19.0%, 28.6%and 44.4%in SxScore low, intermediate and high groups respectively. The incidence rates of MACCE were 12.8%, 23.8%and 45.5%in SxScoreⅡlow, intermediate and high groups respectively. Single factor analysis showed that SxScore, SxScoreⅡ, age, diabetes and left ventricular ejection fraction (LVEF) were the independent predictors of MACCE. Multivariate analysis showed that SxScore and SxScoreⅡwere still risk independent predictors for MACCE. Conclusion Both SxScore and SxScoreⅡare independent risk predictors for MACCE in patients with unprotected left main coronary artery disease undergoing PCI treatment.