1.Combined bilateral asymmetric hip dislocation and anterior shoulder dislocation
Uslu MUSTAFA ; Arican MEHMET ; Saritas AYHAN ; Buyukkaya RAMAZAN ; Kandis HAYATI
World Journal of Emergency Medicine 2012;3(4):311-313
BACKGROUND: Traumatic bilateral hip dislocation is a rare condition. Anterior shoulder dislocation combined with this condition is even a rare occurrence. A 57-year-old man had bilateral asymmetric hip dislocation with a posterior wall fracture of the left acetabulum associated with right shoulder anterior dislocation caused by falling down from a cherry tree. Traumatic hip dislocation and anterior shoulder dislocation represent a true orthopedic emergency. METHODS: Closed reduction was performed immediately for three of the dislocated joints. Posterior wall fracture of the left acetabulum was treated with open reduction and internal fixation by screws. Because of the severity of associated complications like aseptic necrosis or posttraumatic osteoarthritis, efforts were made to ensure prompt diagnosis, therapy and prognosis. RESULTS: The patient was successfully treated by open reduction and internal fixation of the left acetabulum, and discharged from the hospital. CONCLUSION: Traumatic asymmetric hip dislocation and anterior shoulder dislocation are an orthopedic emergency and early diagnosis with immediate reduction of the dislocation is the key determinants of excellent result of treatment.
2.The Effects of Phenyramidol and Diclofenac Treatment on Fracture Healing in Rats
Mücahit ÇELIK ; Zekeriya Okan KARADUMAN ; Yalcın TURHAN ; Mehmet ARICAN ; Mehmet GAMSIZKAN ; Sönmez SAGLAM ; Veysel ULUDAG
Clinics in Orthopedic Surgery 2024;16(5):836-844
Background:
Fracture healing or nonunion refers to a process in which many factors interact. In this study, we aimed to evaluate the radiological, histological, and biomechanical effects of phenyramidol and diclofenac, which are frequently used to treat postfracture ture pain worldwide, on fracture healing and nonunion in a rat femur fracture model.
Methods:
In this study, 72 male Wistar-Albino rats aged 2–3 months and weighing 250 ± 30 g were divided into 4 main groups.The rats were divided into 12 subgroups according to the early, middle, and late periods. A fracture model was created in rat femurs, and surgical fixation was performed. Postoperative analgesic treatment protocols included phenyramidol, diclofenac, phenyramidol + diclofenac, and the control group. The rats were sacrificed on the fifteenth, thirtieth, and forty-fifth days and were evaluated radiologically, histopathologically, and biomechanically.
Results:
Scoring was conducted independently by 2 orthopedists not involved in the study. When the results were analyzed statistically, no statistically significant difference was observed between the fifteenth and thirtieth day radiology score values of the control, diclofenac, phenyramidol, and Phenyramidol + diclofenac groups (p > 0.05), but there was a statistically significant difference (p < 0.05) between the forty-fifth day radiology score values of the control, diclofenac, phenyramidol, and phenyramidol + diclofenac groups.
Conclusions
Our study shows that the use of diclofenac or phenyramidol alone negatively affects postoperative fracture healing.However, this effect was less pronounced in the combined treatment group. Histologic examination revealed that neither treatment had a significant effect on healing. There were statistical differences in biomechanical and radiologic properties between the phenyramidol and diclofenac groups; in particular, the diclofenac group had lower biomechanical properties.
3.The Effects of Phenyramidol and Diclofenac Treatment on Fracture Healing in Rats
Mücahit ÇELIK ; Zekeriya Okan KARADUMAN ; Yalcın TURHAN ; Mehmet ARICAN ; Mehmet GAMSIZKAN ; Sönmez SAGLAM ; Veysel ULUDAG
Clinics in Orthopedic Surgery 2024;16(5):836-844
Background:
Fracture healing or nonunion refers to a process in which many factors interact. In this study, we aimed to evaluate the radiological, histological, and biomechanical effects of phenyramidol and diclofenac, which are frequently used to treat postfracture ture pain worldwide, on fracture healing and nonunion in a rat femur fracture model.
Methods:
In this study, 72 male Wistar-Albino rats aged 2–3 months and weighing 250 ± 30 g were divided into 4 main groups.The rats were divided into 12 subgroups according to the early, middle, and late periods. A fracture model was created in rat femurs, and surgical fixation was performed. Postoperative analgesic treatment protocols included phenyramidol, diclofenac, phenyramidol + diclofenac, and the control group. The rats were sacrificed on the fifteenth, thirtieth, and forty-fifth days and were evaluated radiologically, histopathologically, and biomechanically.
Results:
Scoring was conducted independently by 2 orthopedists not involved in the study. When the results were analyzed statistically, no statistically significant difference was observed between the fifteenth and thirtieth day radiology score values of the control, diclofenac, phenyramidol, and Phenyramidol + diclofenac groups (p > 0.05), but there was a statistically significant difference (p < 0.05) between the forty-fifth day radiology score values of the control, diclofenac, phenyramidol, and phenyramidol + diclofenac groups.
Conclusions
Our study shows that the use of diclofenac or phenyramidol alone negatively affects postoperative fracture healing.However, this effect was less pronounced in the combined treatment group. Histologic examination revealed that neither treatment had a significant effect on healing. There were statistical differences in biomechanical and radiologic properties between the phenyramidol and diclofenac groups; in particular, the diclofenac group had lower biomechanical properties.
4.The Effects of Phenyramidol and Diclofenac Treatment on Fracture Healing in Rats
Mücahit ÇELIK ; Zekeriya Okan KARADUMAN ; Yalcın TURHAN ; Mehmet ARICAN ; Mehmet GAMSIZKAN ; Sönmez SAGLAM ; Veysel ULUDAG
Clinics in Orthopedic Surgery 2024;16(5):836-844
Background:
Fracture healing or nonunion refers to a process in which many factors interact. In this study, we aimed to evaluate the radiological, histological, and biomechanical effects of phenyramidol and diclofenac, which are frequently used to treat postfracture ture pain worldwide, on fracture healing and nonunion in a rat femur fracture model.
Methods:
In this study, 72 male Wistar-Albino rats aged 2–3 months and weighing 250 ± 30 g were divided into 4 main groups.The rats were divided into 12 subgroups according to the early, middle, and late periods. A fracture model was created in rat femurs, and surgical fixation was performed. Postoperative analgesic treatment protocols included phenyramidol, diclofenac, phenyramidol + diclofenac, and the control group. The rats were sacrificed on the fifteenth, thirtieth, and forty-fifth days and were evaluated radiologically, histopathologically, and biomechanically.
Results:
Scoring was conducted independently by 2 orthopedists not involved in the study. When the results were analyzed statistically, no statistically significant difference was observed between the fifteenth and thirtieth day radiology score values of the control, diclofenac, phenyramidol, and Phenyramidol + diclofenac groups (p > 0.05), but there was a statistically significant difference (p < 0.05) between the forty-fifth day radiology score values of the control, diclofenac, phenyramidol, and phenyramidol + diclofenac groups.
Conclusions
Our study shows that the use of diclofenac or phenyramidol alone negatively affects postoperative fracture healing.However, this effect was less pronounced in the combined treatment group. Histologic examination revealed that neither treatment had a significant effect on healing. There were statistical differences in biomechanical and radiologic properties between the phenyramidol and diclofenac groups; in particular, the diclofenac group had lower biomechanical properties.
5.The Effects of Phenyramidol and Diclofenac Treatment on Fracture Healing in Rats
Mücahit ÇELIK ; Zekeriya Okan KARADUMAN ; Yalcın TURHAN ; Mehmet ARICAN ; Mehmet GAMSIZKAN ; Sönmez SAGLAM ; Veysel ULUDAG
Clinics in Orthopedic Surgery 2024;16(5):836-844
Background:
Fracture healing or nonunion refers to a process in which many factors interact. In this study, we aimed to evaluate the radiological, histological, and biomechanical effects of phenyramidol and diclofenac, which are frequently used to treat postfracture ture pain worldwide, on fracture healing and nonunion in a rat femur fracture model.
Methods:
In this study, 72 male Wistar-Albino rats aged 2–3 months and weighing 250 ± 30 g were divided into 4 main groups.The rats were divided into 12 subgroups according to the early, middle, and late periods. A fracture model was created in rat femurs, and surgical fixation was performed. Postoperative analgesic treatment protocols included phenyramidol, diclofenac, phenyramidol + diclofenac, and the control group. The rats were sacrificed on the fifteenth, thirtieth, and forty-fifth days and were evaluated radiologically, histopathologically, and biomechanically.
Results:
Scoring was conducted independently by 2 orthopedists not involved in the study. When the results were analyzed statistically, no statistically significant difference was observed between the fifteenth and thirtieth day radiology score values of the control, diclofenac, phenyramidol, and Phenyramidol + diclofenac groups (p > 0.05), but there was a statistically significant difference (p < 0.05) between the forty-fifth day radiology score values of the control, diclofenac, phenyramidol, and phenyramidol + diclofenac groups.
Conclusions
Our study shows that the use of diclofenac or phenyramidol alone negatively affects postoperative fracture healing.However, this effect was less pronounced in the combined treatment group. Histologic examination revealed that neither treatment had a significant effect on healing. There were statistical differences in biomechanical and radiologic properties between the phenyramidol and diclofenac groups; in particular, the diclofenac group had lower biomechanical properties.