The authors reviewed findings of enhanced abdominal computed tomographic (CT) scans to the difference between a higher dose of conventional ionic contrast media(iothalamate meglumine) and a lower dose of a new, nonionic contrast material (ioversol). One hundred adult patients were divided into two groups. Each group consisted of 50 patients. Iothalamate meglumine and ioversol were intravenously administered in each group. The ratio of the male to female in the former was 28.22, and the latter 29:21. We examine the degree of renal streak artifact and measure the Hounsfield number of urine in renal collecting system. There were significant differences of the degree of the streak artifact depending upon the osmolality of contrast media used and that was related with urine CT number (P value<0.005). We authors conclude that nonionic low osmolar contrast media is prone to cause streak artifacts and distortions of renal image than conventional ionic high osmolar contrast media.
Adult ; Artifacts* ; Contrast Media* ; Female ; Humans ; Iothalamate Meglumine ; Kidney* ; Male ; Osmolar Concentration

Conray ventriculography is a method for the roentgenographic visualization of the cerebral ventricular system with meglumine iothalamate 60%(Conray). Although it has been known that ventriculography using Conray 60% offers definite advantages compared to that with other contrast media and untoward reactions have been reported as mild and transitory ones, a significant disadvantage is the possible development of seizures. Recently we had performed Conray ventriculogrqaphy and analized their untoward reactions in 25 cases which were previously proved hydrocephalic by cerebral angiographies, from march, 1973 to August, 1974. They included twenty cases of brain tumor and five cases of hydrocephalus. Untoward reactions were analized with respect to the different concentration of the contrast media used, communicating or noncommunicating pathway of the cerebrospinal fluid and the different sites of obstruction in the cerebrospinal fluid pathway. The results were as follows: 1. Headache and convulsion were more frequently observed in cases of ventriculography using undiluted Conray. 2. High frequency of vomiting was observed in cases with communicating pathway of the cerebrospinal fluid. 3. There seemed to be no difference in untoward reactions between the levels of obstruction in the cerebrospinal fluid pathway.
Brain Neoplasms ; Cerebral Angiography ; Cerebrospinal Fluid ; Contrast Media ; Headache ; Hydrocephalus ; Iothalamate Meglumine ; Seizures ; Vomiting

No abstract available.
Barium* ; Child* ; Diatrizoate Meglumine* ; Humans ; Intussusception*

Meconium plug syndrome (MPS) is the mildest and most common form of functional distal obstruction in the newborn. It is a transient obstruction of the distal colon and occasionally small bowel that is caused by inspissated immobile meconium. Neonates with MPS commonly presented with abdominal distension, bilious vomiting and problem with passage of meconium plugs. A plain abdominal radiograph often reveals generalized gaseous distention of the small bowel loops without an air-fluid level. A contrast enema is diagnostic, showing the outline of the meconium plug, and therapeutic if the plugs are passed out. In some cases of MPS there is failure to pass the meconium with the contrast enema, and emergent surgery is then required. We report here two cases of MPS that were diagnosed and treated by exploratory laparotomy and one case treated with Gastrografin enema.
Colon ; Diatrizoate Meglumine ; Enema ; Humans ; Infant, Newborn ; Laparotomy ; Meconium* ; Vomiting

Since 1929, the iodine compounds were used intravenous pyelogram by the Swick, it was accepted for the use of intravenous pyelogram in the worldwide. Nevertheless, it has several minor and major side reactions, also it has been used to IVP or cholecystography at X-ray room without prepared for side reaction or resuscitation. We have experienced a case of sever hypersensitivity reaction with the urografin during IVP at X-ray room. Here, we review with the several articles including its etiology, symptoms and treatments. Especially, we classified the mild and severe reactionsby David and Frederick from Table 1 Table 6. Furthermore we considered that t is necessary to prepared the resuscitating instruments during IVP with urografin under local or general anesthesia.
Anesthesia, General ; Cholecystography ; Diatrizoate Meglumine* ; Hypersensitivity* ; Iodine Compounds ; Resuscitation

PURPOSE: We compared the use of diluted gastrografin enema- and air enema CT for the evaluation of the diagnostic accuracy of preoperative lesion detection and the staging of colorectal carcinoma. MATERIALS AND METHODS: Forty-two patients (43 lesions) with colorectal carcinoma, diagnosed by barium enema and/or colonoscopy, underwent preoperative diluted (2.5%) gastrografin enema CT, and in another 26 patients (27 lesions) with colorectal carcinoma, air enema CT was performed. The presence or absence of lesion, its spread (T), and peritumoral lymph node (N) were analyzed. All patients underwent surgery and pathologic confirmation was obtained. RESULTS: Gastrografin enema CT and air enema CT demonstrated the primary tumor in 97.7% (42 of 43) and 96.3% of cases (26 of 27), respectively. A comparison of gastrografin enema CT and the pathologic results showed that the disease was correctly staged as T2 in five of six cases, as T3 in 28 of 31, and as T4 in two of five. Using air enema CT, the disease was correctly staged as T2 in three of three cases, as T3 in 17 of 21, and as T4 in one of two. Overall, carcinoma was correctly staged by gastrografin enema CT in 83% of cases (35 of 42) and by air enema CT in 81% (21 of 26). Nodal involvement was accurately detected in 64% of cases (27 of 42) using gastrografin enema CT and in 69% (18 of 26) using air enema CT. CONCLUSIONS: These findings suggest that the use of gastrografin enema or air enema CT does not significantly affect the diagnostic outcome.
Barium ; Colonoscopy ; Colorectal Neoplasms* ; Diatrizoate Meglumine ; Enema* ; Humans ; Lymph Nodes

PURPOSE: We compared the use of diluted gastrografin enema- and air enema CT for the evaluation of the diagnostic accuracy of preoperative lesion detection and the staging of colorectal carcinoma. MATERIALS AND METHODS: Forty-two patients (43 lesions) with colorectal carcinoma, diagnosed by barium enema and/or colonoscopy, underwent preoperative diluted (2.5%) gastrografin enema CT, and in another 26 patients (27 lesions) with colorectal carcinoma, air enema CT was performed. The presence or absence of lesion, its spread (T), and peritumoral lymph node (N) were analyzed. All patients underwent surgery and pathologic confirmation was obtained. RESULTS: Gastrografin enema CT and air enema CT demonstrated the primary tumor in 97.7% (42 of 43) and 96.3% of cases (26 of 27), respectively. A comparison of gastrografin enema CT and the pathologic results showed that the disease was correctly staged as T2 in five of six cases, as T3 in 28 of 31, and as T4 in two of five. Using air enema CT, the disease was correctly staged as T2 in three of three cases, as T3 in 17 of 21, and as T4 in one of two. Overall, carcinoma was correctly staged by gastrografin enema CT in 83% of cases (35 of 42) and by air enema CT in 81% (21 of 26). Nodal involvement was accurately detected in 64% of cases (27 of 42) using gastrografin enema CT and in 69% (18 of 26) using air enema CT. CONCLUSIONS: These findings suggest that the use of gastrografin enema or air enema CT does not significantly affect the diagnostic outcome.
Barium ; Colonoscopy ; Colorectal Neoplasms* ; Diatrizoate Meglumine ; Enema* ; Humans ; Lymph Nodes

OBJECTIVE: We wanted to report on our experience with modified radiology-guided percutaneous gastrostomy (MRPG) without endoscopic or nasogastric access for treating patients with complete obstruction of the upper digestive tract. MATERIALS AND METHODS: Fourteen oncology patients (13 had hypopharyngeal cancer and 1 had upper esophageal cancer) with complete obstruction of the upper digestive tract were recruited. Conventional percutaneous endoscopic gastrostomy (PEG) and radiologic (fluoroscopy-guided) percutaneous gastrostomy (RPG) were not feasible in all the patients. An MRPG technique (with a combination of ultrasound, an air enema and fluoroscopic guidance) was performed in these patients. RESULTS: We achieved successfully percutaneous gastrostomy using the modified technique in all patients without any major or minor complications after the procedure. CONCLUSION: A modified radiology-guided percutaneous gastrostomy technique can be safely performed in patients who failed to receive conventional PEG or RPG due to the absence of nasogastric access in the completely obstructed upper digestive tract.
Adult ; Aged ; Conscious Sedation ; Contrast Media/diagnostic use ; Esophageal Neoplasms/radiography/*surgery ; Female ; Gastrostomy/*methods ; Humans ; Intestinal Obstruction/radiography/*surgery ; Iothalamate Meglumine/diagnostic use ; Laryngeal Neoplasms/radiography/*surgery ; Male ; Middle Aged ; Radiography, Interventional ; Retrospective Studies ; Upper Gastrointestinal Tract/radiography/*surgery

PURPOSE: The aim of this study was to determine a safe gastrointestinal contrast agent that could be used in various clinical situations where there is a risk of aspiration using a rabbit model. MATERIALS AND METHODS: 30 healthy white rabbits were used. The rabbits were divided into 5 groups containing six animals each, one control group (anesthesia only) and 4 groups receiving various contrast agents [Solotop (Barium sulphate suspension), Gastrografin (Sodium and meglumine amidotrizoate), and Telebrix (Meglumine ioxitalamate), Visipaque (Iodixanol)]. The contrast agents were injected selectively into a main bronchus via a catheter inserted under fluoroscopy guidance. The rabbits were sacrificed either 1 day or 7 days after injecting the contrast agents, and the tissue reaction of the bronchi and lungs were examined both macro- and microscopically. The level of alveolar septal thickening, peribronchiolar lymphocytic infiltration, pulmonary congestion and edema, inflammatory exudate in the alveoli or bronchiolar lumina, microabscess formation, necrosis, pigmentation of materials injected, and fibropurulent pleurisy were evaluated and graded according to the severity as follows: no change, mild, moderate, marked in degree. RESULTS: The common microscopic findings were alveolar septal thickening and peribronchiolar lymphocytic infiltration. Pulmonary congestion and edema, inflammatory exudate in the alveoli or bronchiolar lumina were observed in 21 out of 24 rabbits receiving the contrast agents. Pigmentation of the materials injected was observed only in the group receiving Solotop. An inflammatory exudate in the alveoli and bronchiolar/bronchial lumina, microabscess formation, and necrosis were noted in most groups, but was more frequent and severe in the group receiving Gastrografin. CONCLUSION: The histopathological reactions of the rabbit lungs after the intrabronchial application of a contrast agent showed variable degrees of inflammatory reactions. Gastrografin produced most severe and extensive reaction, Solotop and Telebrix a moderate reaction, and Visipaque a minimal reaction. Therefore, a non-ionic dimeric contrast agent such as Visipaque may be the safest contrast agent in the lung when a GI tract examination is performed in clinical situations where there is a risk of aspiration.
Animals ; Bronchi ; Catheters ; Contrast Media* ; Diatrizoate Meglumine ; Edema ; Estrogens, Conjugated (USP) ; Exudates and Transudates ; Fluoroscopy ; Gastrointestinal Tract ; Lung* ; Meglumine ; Necrosis ; Pigmentation ; Pleurisy ; Rabbits

PURPOSE: This study is to evaluate the efficacy of small bowel displacement system (SBDS) in post-operative pelvic radiation therapy (RT) of rectal cancer patients by measurement of small bowel volume included in the radiation fields receiving therapeutic dose. MATERIALS AND METHOD: Ten consecutive new rectal cancer patients referred to the department of Radiation Oncology of Samsung Medical Center in May of 1997 were included in this study. All patients were asked to drink Gastrographin before simulation and were laid prone for conventional simulation and CT scans with and without SBDS. The volume of opacified small bowel on CT scans, which was to be included in the radiation fields receiving therapeutic dose, was measured using picture archiving and communication system (PACS). RESULTS: The average small bowel volumes with and without SBDS were 176.0ml (5.2- 415.6ml) and 185.1ml (54.5- 434.2ml), respectively. The changes of small bowel volume with SBDS compared to those without SBDS were more than 10% decrease in three, less than 10% decreaseintwo,lessthan10%increaseinthree,andmorethan10%increaseintwopatients. CONCLUSION: No significant advantage of using SBDS in post-operative pelvic RT for rectal cancer patients has been shown by small bowel volume measurement using CT scan considering additional effort and time needed for simulation and treatment setup.
Diatrizoate Meglumine ; Humans ; Radiation Oncology ; Rectal Neoplasms* ; Tomography, X-Ray Computed