1.Suppression of the Ly6 antigens expression on P815 mastocytoma cells by expressing antisense RNA.
Chung Hee SONN ; Mee Rang PARK ; Young Sang KIM
Korean Journal of Immunology 1993;15(2):209-215
No abstract available.
Mastocytoma*
;
RNA, Antisense*
2.Pneumomediastinum developed during anesthesia.
Mee Young CHUNG ; Hee Soon KIM ; Sung Jin HONG
The Korean Journal of Critical Care Medicine 1991;6(2):131-134
No abstract available.
Anesthesia*
;
Mediastinal Emphysema*
3.The Mediating Effect of Emotional Dissonance in the Relationship between Emotional Labor and Burnout among Clinical Nurses.
Journal of Korean Academy of Nursing Administration 2013;19(5):647-657
PURPOSE: This study was done to identify the mediating effect of emotional dissonance in the relationship between emotional labor and burnout among clinical nurses. METHODS: A cross-sectional survey design was used. The participants were 257 nurses working at three general hospitals located in Seoul and Gyeonggi Province. Data were collected by convenience sampling using self-report questionnaires that consisted of general characteristics, and measures of emotional labor, emotional dissonance and burnout. Data were analyzed with descriptive statistics, t-test, ANOVA, correlation, and multiple regression. RESULTS: The findings of the multiple regression were as follows. First, surface acting of emotional labor showed significant positive effects on emotional dissonance and burnout. Second, when surface acting and emotional dissonance were entered into the regression model at the same time, surface acting showed an insignificant effect on burnout, however, emotional dissonance showed a significant effect. Finally, emotional dissonance had a mediating effect only between surface acting of emotional labor and burnout, not between deep acting and burnout. CONCLUSION: Results of the study suggest that as a way to reduce burnout, nursing administrators should develop educational programs for nurses to perform deep acting of emotional labor instead of surface acting at the moment of truth.
Administrative Personnel
;
Cross-Sectional Studies
;
Gyeonggi-do
;
Hospitals, General
;
Humans
;
Negotiating*
;
Nursing
;
Surveys and Questionnaires
;
Seoul
4.A case of thoracophagus diagnosed by abdominal ultrasonorgaphy at second trimester.
Young Joo CHOI ; Yong Mee LEE ; Kyu Ho CHUNG ; Sang Cheol PARK ; Kyu Hong CHOI
Korean Journal of Obstetrics and Gynecology 1992;35(8):1228-1232
No abstract available.
Female
;
Humans
;
Pregnancy
;
Pregnancy Trimester, Second*
5.Characterization of Haemophilus influenzae by SDS-PAGE, Restriction Enzyme Analysis and rRNA Gene Restriction Patterns.
Young Hee LEE ; Kyu Jam HWANG ; Song Mee BAE ; Ha Yong CHUNG
Journal of the Korean Society for Microbiology 1998;33(1):89-98
Among the fifty-three clinical isolates of Haemophilus influenzae, nineteen isolates including eight isolates of each biotype I-VIII, six of serotype b (Hib) strains and five of nontypeable strains were characterized by SDS-PAGE about outer membrane protein (OMP), restriction enzyme analysis (REA) and rRNA gene restriction pattems. OMP patterns showed to common band patterns in each H. influenzae isolate. Based on the two major proteins, 31KDa-38KDa, isolated strains were classified into 7 subtypes. In the OMP patterns about biotype and serotype, the specific pattern of each biotype was not distinguishable, but all of the serotype b strains were shown identical unique pattern, therefore it made distinctive difference with nontypeable strains. The digested genomic DNAs with EcoRI were identical result with rRNA gene restriction. It was more subdivided into 10 ribotypes. The most common ribotype I and serotype 1 accounted for 6 strains (31.6%) and 7 strains (36.8%) of the 19 clinical isolates, respectively. Hib isolates that were both OMP subtype 1 and ribotype I accounted for 2 strains (10.5%). In the epidemiologically unrelated strains, the putative association between the subtypes could not be confirmed. According to these results, the three methods were discriminatory and appropriate techniques for epidemiological studies of H. influenzae.
DNA
;
Electrophoresis, Polyacrylamide Gel*
;
Genes, rRNA*
;
Haemophilus influenzae type b
;
Haemophilus influenzae*
;
Haemophilus*
;
Influenza, Human
;
Membrane Proteins
;
Restriction Mapping*
;
Ribotyping
6.The Use of Transesophageal Echocardiography for Pulmonary Artery Catheter Placement: Two cases.
Byung Ho LEE ; Jun Seok CHEA ; Chang Jae KIM ; Mee Young CHUNG ; Seon Heu SEO
Korean Journal of Anesthesiology 1997;33(5):953-956
The transesophageal echocardiography (TEE) has been used for the assessment of right and left ventricular function, valvular structure and function, regional wall motion abnormalities and localization of intravascular catheters, cannular and prosthesis. We inserted the pulmonary artery catheter (PAC) under the guidance of intraoperative TEE because of the difficulty of placing PAC with the pressure tracing method in two patients. The PAC was inserted from right atrium to right ventricle with the basal four chamber view and advanced to pulmonary artery through pulmonary valve with the longitudinal view of TEE. We observed typical pulmonary arterial wave form to confirm the correct position. We suggest that the TEE can be used for successful placement of a PAC to facilitate manipulation of the catheter as an alternative method in the patients whose PAC can not be positioned with the pressure tracing method.
Catheters*
;
Echocardiography, Transesophageal*
;
Heart Atria
;
Heart Ventricles
;
Humans
;
Prostheses and Implants
;
Pulmonary Artery*
;
Pulmonary Valve
;
Ventricular Function, Left
7.Expression of Neuroendocrine Cells in Benign Prostatic Hyperplasia and the Effect of Dihydrotestosterone .
Sung Joon HONG ; Soo Mee KWON ; Sun Il KIM ; Hea Young OH ; Bong Chul CHUNG
Korean Journal of Urology 2003;44(3):267-271
PURPOSE: Neuroendocrine (NE) cells of the prostate are considered to be involved in the pathogenesis of benign prostate hyperplasia (BPH). By a comparative analysis of NE cell density in BPH tissue of men who were either exposed to or not exposed to 5alpha-reductase inhibitor, we investigated the relationship between NE cells and BPH, and the effect of androgen deprivation on NE cells. MATERIALS AND METHODS: Prostate tissue specimens, obtained from 30 men by transurethral resection of the prostate or radical cystoprostatectomy, were used. Of the 30 patients, 10 had a prostate smaller than 25 ml (normal control), the other 20 had a prostate larger than 40ml, 10 of who had taken 5alpha-reductase inhibitor (finasteride) for 3 months before surgery (androgen blockade group), and 10 who had not (BPH group). The distribution of NE cells in the prostate was examined using the anti-chromogranin A (CgA) antibody, and the density of the CgA-positive cells was compared by an optical dissector method. Immunoblotting was performed using the neuron specific enolase (NSE) antibody. A Mann-Whitney U test was used in a statistical analysis. RESULTS: Most of the CgA-positive NE cells were localized between the acinar epithelial cells. The mean numbers of CgA-positive NE cells per acinus in the normal controls and the BPH groups were 1.67+/-0.78 and 4.45+/-2.54, respectively, and the difference was statistically significant (p<0.05). However, the mean number of CgA-positive NE cells in the androgen blockade group, was 4.93+/-2.17, which was similar to the BPH group. In a NSE immunoblotting study, a distinct band was observed in the BPH and androgen blockade groups, but the density of the band was higher in the androgen blockade group. CONCLUSIONS: Our results suggest that NE cells may be involved in the hyperplastic process of BPH. Inhibition of dihydrotestosterone, caused by the oral administration of the 5alpha-reductase inhibitor, failed to induce any significant change in the NE cells, probably due to the incomplete androgen blockade.
Administration, Oral
;
Cell Count
;
Dihydrotestosterone*
;
Epithelial Cells
;
Humans
;
Hyperplasia
;
Immunoblotting
;
Male
;
Neuroendocrine Cells*
;
Phosphopyruvate Hydratase
;
Prostate
;
Prostatic Hyperplasia*
8.A Case of Double Primary Cancer in Stomach and Rectum.
Won Young TAK ; Young Mee YUN ; Byung Chul AN ; Sung Rok KIM ; Kyu Sik KWAK ; Young Hwan CHOI ; Joon Mo CHUNG
Korean Journal of Gastrointestinal Endoscopy 1991;11(1):97-100
Double primary cancer is defined as the case of primary malignant tumors, which must be arise in different sites and have a different histologic appearences. The number of reported cases of double primary malignant tumors has increased in recent and the occurrence of multiple primary cancers in the same individuals is one of the interesting subjects for investigation and research in relation to the carcinogenic mechanism and/or genetic factors. We have experienced a case with double primary malignant tumors of different site origins such as stomach adenocarcinoma and rectal adenocarcinoma, which were diagnosed by biopsies with gastro and colono fiberscopy. For its great rarity, we report this case with review of literatures.
Adenocarcinoma
;
Biopsy
;
Rectum*
;
Stomach*
9.Synchronous Double Primary Cancer of Esophageal Small Cell Carcinoma and Gastric Adenocarcinoma.
Joon Mo CHUNG ; Yong Hwan CHOI ; Young Oh KWEON ; Young Mee YUN ; Byeong Cheal AHN ; Sung Kook KIM
Korean Journal of Gastrointestinal Endoscopy 1995;15(3):495-500
Double primary cancer means that more than two cancers with different origin exist independently in an individual. The diagnosis of double primary cancer was determined by following criteria. Each of the tumors must present a definite picture of malignancy, and each must be distinct, and the probability of one being a metastasis of the other must be excluded. Small cell carcinoma has a distinct biological behavior such as, early invasion and metastasis, a rapid clinical course, and significant sensitivity to chemotherapy. Small cell carcinoma in the esophagus is relatively rare, and rarer when it is combined with other malignant disease. We have experienced a case of double primary cancer, a 70-year-old man with esophageal small cell carcinoma and gastric adenocarcinoma, which were diagnosed by gastrointestinal endoscopic biopsy. A review of the Korean medical literature failed to reveal any previously described case of esophageal small cell carcinoma with gastric adenocareinoma. We report this case with review of literatures.
Adenocarcinoma*
;
Aged
;
Biopsy
;
Carcinoma, Small Cell*
;
Diagnosis
;
Drug Therapy
;
Esophagus
;
Humans
;
Neoplasm Metastasis
10.Two Cases of Thin Basement Membrane Nephropathy presented with Minimal Change Nephrotic Syndrome.
Young Mee SEO ; Jae Gul CHUNG ; En Sil YU ; Jin Yeong JEONG ; Young Seo PARK
Journal of the Korean Pediatric Society 2000;43(7):978-982
Thin basement membrane nephropathy(TBMN) is defined histologically as follows: 1) By light rnicroscopy only minor abnormalities are detected in the glomeruli at most minor mesangial widening. 2) By electron microscopy, diffuse thinning of glomerular basement rnembrane is demonstrated. 3) By immunofluorescence, absence of immunoglobulins and complement components is demonstrated. 4) Alport's syndrome and systemic diseases that may affect the glomerular structure have been excluded. TBMN presented frequently with recurrent or persistent microscopic hematuria. Massive proteinuria such as in nephrotic syndrome rarely occurs in TBMN. We reported two cases of TBMN presented with typical minimal change nephrotic syndrome.
Basement Membrane*
;
Complement System Proteins
;
Fluorescent Antibody Technique
;
Hematuria
;
Immunoglobulins
;
Microscopy, Electron
;
Nephritis, Hereditary
;
Nephrosis, Lipoid*
;
Nephrotic Syndrome
;
Proteinuria