BACKGROUND: Diseases related with cardiovascular risk factors such as hypertension, diabetes mellitus, coronary artery disease, hyperlipidemia and cerebrovascular disease are increasing according to the change of dietary patterns with economy growth and other causes such as low physical activity. Many studies showed the effects and benefits of exercise in people who had diseases related to cardiovascular risk factors, but there are few studies on the effects of exercise in healthy people. Therefore this study investigated the influence of exercise on cardiovascular risk factors in healthy adults. METHODS: 2,413 people who participated in periodic health examinations at Taegu medical center from May to July, in 1998 were assessed with respect to height, weight, blood pressure, fasting blood glucose, serum total cholesterol and subjects responded to the self-administered questionnaires. We reviewed 881 subjects. Subjects were classified as exereise group if they reported exercising for at least 30 minutes, 5 or more days of the week, and as control group if they reported exercising once a week or less. We observed the difference in Body Mass Index(BMI), fasting blood glucose, systolic and diastolic blood pressure, serum total cholesterol and the prevalence of overweight, hypertension, hypercholesterolemia, hyperglycemia between study groups. RESULTS: There were no differences in sex, age, education, economic status, occupation between the study groups. Serum total cholesterol, systolic and diastolic blood pressure, fasting blood glucose and BMI were significantly lower for the exercise group. The prevalence of overweight, hypertension, and hyperlipidemia were significantly lower for the exercise group. The prevalence of diabetes mellitus were lower for the exercise group, but were not statistically significant. CONCLUSIONS: In healthy peoples, they who were regularly exercise were significantly lowered in cardiovascular risk factors and diseases related with cardiovascular risk factors than nonexercising peopl
Adult* ; Blood Glucose ; Blood Pressure ; Cholesterol ; Coronary Artery Disease ; Daegu ; Diabetes Mellitus ; Education ; Fasting ; Humans ; Hypercholesterolemia ; Hyperglycemia ; Hyperlipidemias ; Hypertension ; Motor Activity ; Occupations ; Overweight ; Prevalence ; Risk Factors* ; Surveys and Questionnaires

BACKGROUND: Diseases related with cardiovascular risk factors such as hypertension, diabetes mellitus, coronary artery disease, hyperlipidemia and cerebrovascular disease are increasing according to the change of dietary patterns with economy growth and other causes such as low physical activity. Many studies showed the effects and benefits of exercise in people who had diseases related to cardiovascular risk factors, but there are few studies on the effects of exercise in healthy people. Therefore this study investigated the influence of exercise on cardiovascular risk factors in healthy adults. METHODS: 2,413 people who participated in periodic health examinations at Taegu medical center from May to July, in 1998 were assessed with respect to height, weight, blood pressure, fasting blood glucose, serum total cholesterol and subjects responded to the self-administered questionnaires. We reviewed 881 subjects. Subjects were classified as exereise group if they reported exercising for at least 30 minutes, 5 or more days of the week, and as control group if they reported exercising once a week or less. We observed the difference in Body Mass Index(BMI), fasting blood glucose, systolic and diastolic blood pressure, serum total cholesterol and the prevalence of overweight, hypertension, hypercholesterolemia, hyperglycemia between study groups. RESULTS: There were no differences in sex, age, education, economic status, occupation between the study groups. Serum total cholesterol, systolic and diastolic blood pressure, fasting blood glucose and BMI were significantly lower for the exercise group. The prevalence of overweight, hypertension, and hyperlipidemia were significantly lower for the exercise group. The prevalence of diabetes mellitus were lower for the exercise group, but were not statistically significant. CONCLUSIONS: In healthy peoples, they who were regularly exercise were significantly lowered in cardiovascular risk factors and diseases related with cardiovascular risk factors than nonexercising peopl
Adult* ; Blood Glucose ; Blood Pressure ; Cholesterol ; Coronary Artery Disease ; Daegu ; Diabetes Mellitus ; Education ; Fasting ; Humans ; Hypercholesterolemia ; Hyperglycemia ; Hyperlipidemias ; Hypertension ; Motor Activity ; Occupations ; Overweight ; Prevalence ; Risk Factors* ; Surveys and Questionnaires

Clear cell hidradenoma is a tumor that originates from a sweat gland and typically involves the dermis and subcutaneous tissue. Malignant clear cell hidradenoma is very rare, and surgical excision is usually performed without imaging. There are few reports of the ultrasonographic findings of malignant clear cell hidradenomas. Herein, we present the ultrasonographic characteristics of a malignant clear cell hidradenoma.

Clear cell hidradenoma is a tumor that originates from a sweat gland and typically involves the dermis and subcutaneous tissue. Malignant clear cell hidradenoma is very rare, and surgical excision is usually performed without imaging. There are few reports of the ultrasonographic findings of malignant clear cell hidradenomas. Herein, we present the ultrasonographic characteristics of a malignant clear cell hidradenoma.

PURPOSE: Purpose of this study was to investigate the status of depression in academic high school students and path analysis model for exploring the mediating role of entrapment to depression in relation to academic stress and perceived social support. METHODS: Measurements were four reliable questionnaires measuring academic stress, social support, entrapment, and depression. Data were collected from students in 17 high schools in Seoul. RESULTS: Students (n=5,346) completing the questionnaires indicated depression & entrapment from academic stress. Depression was more prevalent in girls, those whose parents' household income was less than two million won, who did not live with father or mother or both due to divorce, separation, or death, and those who smoked or used alcohol. Entrapment was more prevalent in students similar to cases of depression and in seniors. According to the proposed path model, 48.6% of depression was explained by academic stress, social support, and entrapment. The indirect effect of entrapment as a mediator between academic stress and depression was verified and larger than the direct effect of academic stress on depression. CONCLUSION: Considering levels of depression and entrapment demonstrated by these students, better mental health programs with diverse strategies should be developed for their psychological well-being.
Adaptation, Psychological ; Adolescent ; *Depression ; Female ; Humans ; Male ; Questionnaires ; Republic of Korea ; Social Support ; Socioeconomic Factors ; Stress, Psychological ; Students/*psychology ; Young Adult

A 73-year-old man who had undergone a right pneumonectomy and open window thoracostomy due to tuberculous empyema, presented with purulent discharge from the previous operation site. The computed tomography of the chest showed diffuse pleural thickening and a low attenuated lesion, with air bubbles in a dependent portion of the right hemithorax. These air bubbles were revealed to be due to 7 pieces of retained surgical gauze by flexible bronchoscopy. The patient showed marked clinical improvement with diminished purulent discharge after removal of the foreign bodies.
Aged ; Bronchoscopy ; Empyema, Tuberculous ; Foreign Bodies ; Humans ; Pneumonectomy ; Thoracostomy* ; Thorax

PURPOSE: The complication after colostomy formation may place undue hardship and emotional trauma on the ostomates. The purpose of this study was to find the effect of preoperative stoma site marking on postoperative stoma related complication. METHODS: We recruited 127 colostomy patients who underwent sigmoid or descending end colostomy, by elective operation. Transverse colostomy, loop colostomy, and emergency operation were excluded in this study. We divided the patients into two groups according to pre-operative stoma site marking by an enterostomal therapist. Postoperative stoma related complications were compared and analysed prospectively using chi-square test and paired t-test. Significance was assigned to a P value of < 0.05. RESULTS: Among 127 patients, 49 were marked preoperatively (marking group) while 78 were not marked (non- marking group). Overall stoma related complications were developed in 32 (25%) cases. Major complications including prolapse, parastomal hernia, stenosis were developed in 10 (8%) cases and minor complications including peristomal dermatitis and wound infection were developed in 22 (17%) cases. Stoma related complications were developed in 7 (14%) cases in the marking group and 25 (32%) cases in the non-marking group (P<0.05). Major complications were developed in 2 (4%) cases in the marking group and 8 (10%) cases in the non-marking group. Minor complications were developed in 5 (10%) cases in the marking group and 17 (22%) cases in the non-marking group. However, the difference in major and minor complications between the groups was not statistically significant. Of minor complications in the non-marking group, 9 (53%) cases due solely to postoperative frequent stool leakage caused by inappropriate location of the stoma. However, in the marking group, postoperative stool leakage was not observed. CONCLUSIONS: Preoperative stoma site marking by an enterostomal therapist may reduce postoperative stoma related complication. All elective procedure that result in stoma formation should be assessed and marked preoperatively.
Colon, Sigmoid ; Colostomy ; Constriction, Pathologic ; Dermatitis ; Emergencies ; Hernia ; Humans ; Prolapse ; Prospective Studies ; Wound Infection

BACKGROUND: Absence of CD34-positive fibroblasts was reported within the stroma associated with invasive carcinomas. Conversely, tumor-associated desmoplastic stroma is characterized by the presence of smooth muscle actin (SMA)-reactive myofibroblasts. The present study was undertaken in order to elucidate whether the different distributions of stromal CD34-positive fibroblasts and SMA-reactive myofibroblasts are sensitive or specific markers of tumor invasion in small lung adenocarcinomas. METHODS: Immunohistochemical stainings for CD34 and SMA were done in 37 peripheral adenocarcinomas less than 3.0 cm in diameter, including 16 adenocarcinomas with bronchioloalveolar carcinoma (BAC) and invasive components (mixed), and 21 invasive adenocarcinomas without BAC components (invasive). RESULTS: The fibroblasts within the BAC components of the mixed group were mainly CD34-positive (81.2%) and preferentially SMA-negative (56.3%). In contrast, the fibroblasts within the invasive components of the mixed group were mainly CD34-negative (75.0%) and SMApositive (87.5%). The stromal cells of the invasive group were mostly negative for CD34 (90.5%) and positive for SMA (95.3%). CONCLUSIONS: The loss of CD34 and the acquisition of SMA in the stromal cells within the tumor were related to tumor invasion (p<0.05). Thus, expression patterns of CD34 and SMA can be used to detect small foci of early stromal invasion in adenocarcinomas of the lung.
Actins* ; Adenocarcinoma* ; Adenocarcinoma, Bronchiolo-Alveolar ; Fibroblasts ; Lung* ; Muscle, Smooth* ; Myofibroblasts ; Neoplasm Invasiveness ; Stromal Cells

Hypereosinophilic syndrome (HES) is characterized by a sustained eosinophilia of 1,500/mm3 or more in the absence of any known causes or the signs and symptoms of organ involvement. We report a 64-year-old man with HES initially presenting with involvement of the liver and bone marrow. Despite controlling the eosinophilia by corticosteroid, he developed a cerebral infarction and later progressive interstitial pneumonia. Brain angiography revealed a severe stenosis of the proximal right internal carotid artery (ICA) and a complete obstruction of the intracranial ICA. An open lung biopsy revealed fibrosis and lymphoplasma cell infiltration without eosinophils, which were consistent with nonspecific interstitial pneumonia.
Angiography ; Biopsy ; Bone Marrow ; Brain ; Carotid Artery, Internal ; Cerebral Infarction ; Constriction, Pathologic ; Eosinophilia ; Eosinophils ; Fibrosis ; Humans ; Hypereosinophilic Syndrome* ; Liver ; Lung Diseases, Interstitial ; Lung* ; Middle Aged

In recent years, next-generation sequencing (NGS)–based genetic testing has become crucial in cancer care. While its primary objective is to identify actionable genetic alterations to guide treatment decisions, its scope has broadened to encompass aiding in pathological diagnosis and exploring resistance mechanisms. With the ongoing expansion in NGS application and reliance, a compelling necessity arises for expert consensus on its application in solid cancers. To address this demand, the forthcoming recommendations not only provide pragmatic guidance for the clinical use of NGS but also systematically classify actionable genes based on specific cancer types. Additionally, these recommendations will incorporate expert perspectives on crucial biomarkers, ensuring informed decisions regarding circulating tumor DNA panel testing.