1.Localized Thymic Amyloidosis Presenting with Myasthenia Gravis: Case Report.
Seung Myoung SON ; Yong Moon LEE ; Si Wook KIM ; Ok Jun LEE
Journal of Korean Medical Science 2014;29(1):145-148
A mediastinal mass was incidentally found on chest radiography in a 46-yr-old woman who had had myasthenia gravis (MG) for 2 months. Computed tomography revealed a 4-cm in size, well-defined, and lobulating mass with nodular calcification that was located in the thymus. Microscopically, the mass consisted of diffuse amorphous eosinophilic materials. These deposits exhibited apple-green birefringence under polarized light microscopy after Congo red staining. Immunohistochemical analysis revealed that they were positive for both kappa and lambda light chains and negative for amyloid A. A diagnosis of localized primary thymic amyloidosis was finally made. After thymectomy, the symptoms of MG were controlled with reduced corticosteroid requirements. Localized thymic amyloidosis associated with MG has not been reported to date.
Amyloidosis/complications/*radiography/*surgery
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Calcinosis/*radiography/*surgery
;
Female
;
Humans
;
Immunoglobulin kappa-Chains/immunology
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Immunoglobulin lambda-Chains/immunology
;
Mediastinum/radiography/surgery
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Middle Aged
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Myasthenia Gravis/*complications
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Radiography, Thoracic
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Thymectomy
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Thymus Gland/radiography/surgery
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Tomography, X-Ray Computed
2.Mediastinal impalement with a fibreglass sheet.
Welege Samantha Buddhika WIMALACHANDRA ; Atasha ASMAT
Singapore medical journal 2014;55(9):e148-9
Mediastinal impalement injuries are uncommon and often fatal. There have been very few reported cases of survival following mediastinal impalement. Patients who present with these injuries always undergo operative intervention regardless of their underlying haemodynamic status or associated injuries. We herein present a case of mediastinal impalement injury, where a sheet of fibreglass had fractured the manubrium and entered the anterior mediastinum with no associated great vessel injury. The fibreglass sheet was removed via a partial sternotomy and the patient made an uneventful postoperative recovery.
Adult
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Foreign Bodies
;
surgery
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Glass
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Humans
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Male
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Mediastinum
;
surgery
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Occupational Injuries
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Radiography, Thoracic
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Sternotomy
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Thoracic Injuries
;
surgery
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Tomography, X-Ray Computed
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Wounds, Penetrating
;
surgery
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Wounds, Stab
;
surgery
3.Cardiac echinococcosis.
Hua REN ; Heng ZHANG ; Chao-ji ZHANG ; Zhen-zong DU
Chinese Medical Sciences Journal 2005;20(4):276-278
4.A late onset solitary mediastinal cystic lymphangioma in a 66-year-old woman who underwent kidney transplantation.
Jung Mo LEE ; Sang Hoon LEE ; Youngmok PARK ; Chi Young KIM ; Eun Kyoung GOAG ; Eun Hye LEE ; Ji Eun PARK ; Chang Young LEE ; Se Kyu KIM
Yeungnam University Journal of Medicine 2015;32(2):155-158
Lymphangioma is a congenital abnormality of the lymphatic system detected primarily in early childhood. There are rare reports of mediastinal lymphangioma in older adults. We hereby report on a 66-year-old female patient who underwent kidney transplantation 20 years previously and who developed pathologically confirmed solitary mediastinal lymphangioma 1 year ago. Chest radiography showed a mediastinal nodule, which was not observed 2 year previously, therefore she was referred to the pulmonary division. She had no symptoms, and chest computed tomography demonstrated a 25-mm, well-defined, low-density nodule located at the anterior mediastinum. The size of the nodule had increased from 25 mm to 34 mm 1 year later, and it was completely resected via video-assisted thoracic surgery. The histological diagnosis was cystic lymphangioma. Therefore, we recommend that clinicians consider cystic lymphangioma as a possible diagnosis even in older patients with a mediastinal cystic mass that shows progressive enlargement.
Adult
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Aged*
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Congenital Abnormalities
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Diagnosis
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Female
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Humans
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Kidney Transplantation*
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Kidney*
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Lymphangioma*
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Lymphangioma, Cystic
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Lymphatic System
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Mediastinal Cyst*
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Mediastinum
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Radiography
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Thoracic Surgery, Video-Assisted
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Thorax
5.A rare mediastinal tumour with spinal cord involvement in an adult.
Anand MANI ; Sanjay D DESHMUKH ; Pramod V LOKHANDE
Annals of the Academy of Medicine, Singapore 2011;40(9):432-433
Fatal Outcome
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Humans
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Magnetic Resonance Imaging
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Male
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Mediastinal Neoplasms
;
complications
;
diagnostic imaging
;
pathology
;
surgery
;
Mediastinum
;
diagnostic imaging
;
pathology
;
Neuroectodermal Tumors, Primitive, Peripheral
;
complications
;
diagnostic imaging
;
pathology
;
surgery
;
Radiography
;
Spinal Cord Diseases
;
diagnostic imaging
;
etiology
;
pathology
;
Young Adult