1.Teratoma with Malignant Transformation in the Anterior Mediastinum: A Case Report.
Jung Im JUNG ; Seog Hee PARK ; Jae Gil PARK ; Sun Hee LEE ; Kyo Young LEE ; Seong Tai HAHN
Korean Journal of Radiology 2000;1(3):162-164
Malignant transformation of teratoma in the anterior mediastinum is rare; the mass usually has a long history and is seen in older patients. We report a case of teratoma with malignant transformation in the anterior mediastinum, complicated by rupture. CT revealed a lobulated, inhomogeneous cystic mass with a fat com-ponent and wall calcifications. The lateral wall was disrupted and consolidation in the adjacent left upper lobe was noted, suggesting rupture. A heterogeneously enhanced solid portion, obliterating the fat plane between the mass and the great vessels was present in the medial aspect of the mass, and pathologic examina-tion demonstrated the presence of adenocarcinoma.
Adenocarcinoma/pathology
;
Human
;
Male
;
Mediastinal Neoplasms/pathology/*radiography
;
Mediastinum/pathology
;
Middle Age
;
Rupture, Spontaneous
;
Teratoma/pathology/*radiography
2.Angiolipoma of the Posterior Mediastinum with Extension into the Spinal Canal: A Case Report.
Ja Young CHOI ; Jin Mo GOO ; Myung Jin CHUNG ; Hyo Cheol KIM ; Jung Gi IM
Korean Journal of Radiology 2000;1(4):212-214
Angiolipoma is a rare benign soft tissue tumor, an unusual variant of lipoma,consisting of fatty and vascular components and located in the subcutis, usually in the trunk and extremities. We report a case of posterior mediastinal angiolipo-ma extending into the spinal canal and showing both fat and angiomatous fea-tures on CT scan.
Aged
;
Angiolipoma/pathology/*radiography
;
Case Report
;
Female
;
Human
;
Mediastinal Neoplasms/pathology/*radiography
;
Spinal Canal/*pathology
;
Tomography, X-Ray Computed
3.Primary Malignant Melanoma of the Mediastinum: Radiologic and Pathologic Correlation in Two Case.
Sun Young PARK ; Mi Young KIM ; Eun Jin CHAE
Korean Journal of Radiology 2012;13(6):823-826
Primary malignant melanoma of the anterior mediastinum is extremely rare, accounting for 0.1-0.5% of all primary malignant neoplasms. These tumors may be mistakenly diagnosed as lymphomas, thymic carcinomas and malignant germ-cell tumors of the mediastinum. We describe two cases of primary malignant melanomas of the anterior mediastinum and report their CT and pathology findings.
Adult
;
Female
;
Humans
;
Male
;
Mediastinal Neoplasms/pathology/*radiography
;
Melanoma/pathology/*radiography
;
Middle Aged
;
Tomography, X-Ray Computed
4.Mediastinal Lymphangioma and Chylothorax: Thoracic Involvement of Gorham's Disease.
So Young YOO ; Jin Mo GOO ; Jung Gi IM
Korean Journal of Radiology 2002;3(2):130-132
We report a case of mediastinal lymphangioma associated with Gorham's disease in a 38-year-old man who had suffered recurrent clavicular fractures during a seven-year period. Mediastinal widening associated with osteolysis of the clavicles and the sternal manubrium was revealed by chest radiography, while computed tomography demonstrated a cystic anterior mediastinal mass infiltrating mediastinal fat and associated with osseous destruction of the clavicles and manubrium. Chylothorax recurred during the course of the disease.
Adult
;
Case Report
;
Chylothorax/*complications
;
Human
;
Lymphangioma/*complications/radiography
;
Male
;
Mediastinal Neoplasms/*complications/radiography
;
Osteolysis, Essential/*complications/pathology/radiography
;
Thoracic Vertebrae/*pathology
;
Tomography, X-Ray Computed
5.Imaging Findings of Follicular Dendritic Cell Sarcoma: Report of Four Cases.
Qiu LONG-HUA ; Xiao QIN ; Gu YA-JIA ; Wang JIAN ; Feng XIAO-YUAN
Korean Journal of Radiology 2011;12(1):122-128
Follicular dendritic cell sarcoma is a rare malignant neoplasm and little is known about its radiological features. We present here four cases of follicular dendritic cell sarcomas and we provide the image characteristics of these tumors to help radiologists recognize this entity when making a diagnosis.
Adult
;
Dendritic Cell Sarcoma, Follicular/pathology/*radiography
;
Diagnosis, Differential
;
Female
;
Gastrointestinal Neoplasms/radiography
;
Head and Neck Neoplasms/pathology/radiography
;
Humans
;
Male
;
Mediastinal Neoplasms/radiography
;
Middle Aged
;
Tomography, X-Ray Computed
6.A rare mediastinal tumour with spinal cord involvement in an adult.
Anand MANI ; Sanjay D DESHMUKH ; Pramod V LOKHANDE
Annals of the Academy of Medicine, Singapore 2011;40(9):432-433
Fatal Outcome
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Mediastinal Neoplasms
;
complications
;
diagnostic imaging
;
pathology
;
surgery
;
Mediastinum
;
diagnostic imaging
;
pathology
;
Neuroectodermal Tumors, Primitive, Peripheral
;
complications
;
diagnostic imaging
;
pathology
;
surgery
;
Radiography
;
Spinal Cord Diseases
;
diagnostic imaging
;
etiology
;
pathology
;
Young Adult
7.Dysphagia due to mediastinal tuberculous lymphadenitis presenting as an esophageal submucosal tumor: a case report.
Seung Ho PARK ; Jun Pyo CHUNG ; In Jae KIM ; Hyo Jin PARK ; Kwan Sik LEE ; Chae Yoon CHON ; In Suh PARK ; Ki Whang KIM ; Doo Yun LEE
Yonsei Medical Journal 1995;36(4):386-391
Mediastinal tuberculous lymphadenitis is rare in adults, and it is even rarer for dysphagia to be the presenting symptom of mediastinal tuberculous lymphadenitis. Mediastinal tuberculous lymphadenitis with esophageal symptoms has been presented as esophageal ulceration, mucosal or submucosal mass with ulceration, fistula or sinus formation, extrinsic compression, or displacement of the esophagus. An exaggerated form of extrinsic compression may be presented as a submucosal tumor, radiologically or endoscopically. A barium esophagography of a 34 year-old woman with painful dysphagia revealed a large submucosal tumor-like mass on the mid-esophagus. The symptom was spontaneously improved over a 3-week period together with reduction of the mass size. A computed tomography of the chest disclosed an enlarged subcarinal lymph node and histologic examination of the specimen obtained by thoracoscopic biopsy brought about a diagnosis of tuberculosis. We herein report a case of mediastinal tuberculosis with unusual manifestations.
Adult
;
Case Report
;
Deglutition Disorders/*etiology
;
Diagnosis, Differential
;
Esophageal Neoplasms/*diagnosis
;
Esophagoscopy
;
Esophagus/pathology/radiography
;
Female
;
Human
;
Mediastinal Diseases/*complications/*diagnosis
;
Radiography, Thoracic
;
Tomography, X-Ray Computed
;
Tuberculosis, Lymph Node/*complications/*diagnosis
8.Embryonal Rhabdomyosarcoma Arising from a Mediastinal Teratoma: An Unusual Case Report.
Young Joon RYU ; Su Hyun YOO ; Min Jung JUNG ; Sejin JANG ; Kyung Ja CHO
Journal of Korean Medical Science 2013;28(3):476-479
We report an unusual case of 9.5-cm-sized embryonal rhabdomyosarcoma arose from a mediastinal mature teratoma in a 46-yr-old man. A man presented with chest trauma as a result of an accident at 10 September 2011. On chest X-ray, an anterior mediastinal mass was detected. To obtain further information, chest computed tomography (CT) with contrast enhancement was performed, revealing an anterior mediastinal mass. Complete surgical excision was performed and entire specimen was evaluated. Pathologic diagnosis was embryonal rhabdomyosarcoma arising in mature cystic teratoma. After surgical excision, two cycles of dactinomycin-based chemotherapy were performed. Lung metastasis was detected on follow up CT in September 2012, and wedge resection was performed. Pathological finding of the lung lesion showed same feature with that of primary rhabdomyosarcoma.
Antibiotics, Antineoplastic/therapeutic use
;
Dactinomycin/therapeutic use
;
Desmin/metabolism
;
Humans
;
Immunohistochemistry
;
Lung Neoplasms/radiography/secondary/surgery
;
Male
;
Mediastinal Neoplasms/*diagnosis/pathology
;
Middle Aged
;
Neoplasms, Germ Cell and Embryonal/drug therapy/*radiography/surgery
;
Rhabdomyosarcoma, Embryonal/drug therapy/*radiography/surgery
;
Teratoma/*diagnosis/pathology
;
Tomography, X-Ray Computed
9.Clinicopathologic and immunohistochemical study of 23 cases of mesenchymal chondrosarcoma.
Zong-guo PANG ; Xing-zhuang HE ; Lan-yan WU ; Wei WEI ; Xiao-yu LIU ; Dian-ying LIAO ; Feng-yuan LI ; Xian-liang ZHANG
Chinese Journal of Pathology 2011;40(6):368-372
OBJECTIVETo study the clinicopathologic and immunohistochemical features of mesenchymal chondrosarcoma.
METHODSThe clinical and histologic features of 23 cases of mesenchymal chondrosarcoma were analyzed. Immunohistochemical study was also performed in 14 of the cases.
RESULTSThe age of patients ranged from 12 to 47 years. Fourteen of them occurred in males. Thirteen cases involved the bony skeleton and 5 cases affected the soft tissue. The patients presented with pain and/or swelling. Histologically, the tumor consisted of a mixture of undifferentiated small round cells and hyaline cartilage. Transition between the two components was demonstrated and growth plate-like cartilage was observed. Immunohistochemical study showed that the small round cells were positive for Sox9 (14/14), CD99 (12/14), vimentin (6/14), CD56 (4/14), CD57 (4/14), neuron-specific enolase (3/14) and desmin(1/14). They were negative for Coll-II, S-100 protein, epithelial membrane antigen, pan-cytokeratin, synaptophysin, chromogranin A, CD34 and c-erbB2.
CONCLUSIONSMesenchymal chondrosarcoma is a rare malignant tumor. Thorough histologic examination, when coupled with immunohistochemical findings, is helpful in arriving at a correct diagnosis.
12E7 Antigen ; Adolescent ; Adult ; Antigens, CD ; metabolism ; Bone Neoplasms ; diagnostic imaging ; metabolism ; pathology ; surgery ; Cell Adhesion Molecules ; metabolism ; Child ; Chondrosarcoma, Mesenchymal ; diagnostic imaging ; metabolism ; pathology ; secondary ; surgery ; Female ; Follow-Up Studies ; Humans ; Immunohistochemistry ; Lung Neoplasms ; secondary ; Male ; Mediastinal Neoplasms ; diagnostic imaging ; metabolism ; pathology ; surgery ; Middle Aged ; Neoplasm Recurrence, Local ; Orbital Neoplasms ; diagnostic imaging ; metabolism ; pathology ; surgery ; Radiography ; SOX9 Transcription Factor ; metabolism ; Vimentin ; metabolism ; Young Adult