1.Prognosis in children with traumatic injuries referring to the emergency department
Akbaryan FARZAD ; Derakhshanfar HOJJAT ; Heidari KAMRAN ; Vafaei ALI ; Matin SOMAIEH
Chinese Journal of Traumatology 2019;22(6):323-327
Purpose:Trauma may lead to serious complications in children patients.The purpose of this study was to investigate prognosis in children with traumatic injuries.Methods:This cross-sectional study was conducted on all of the children (<18 years old) who had suffered traumatic injuries and transferred to the emergency department of Imam Hussein Hospital by emergency medical services.After selecting the children,a checklist including information such as demographic characteristics,trauma type,consciousness level,and final outcome was recorded.Finally,the data were analyzed using t-test,Chi-square test and ANOVA.Results:In total of 564 children were investigated.Among them,70% were males,and 33.2% were in the age range of 5-12 years.The mechanism of injuries in 97.9% of the cases was blunt trauma.The most common chief complaint among the affected children was nausea.The majority of them had stable vital signs and normal neurological tests results.However,1.06% of them died during hospitalization.The results indicated that the final outcome in the children affected by traumatic injuries is significantly related to the type of trauma,the location of traumatic event,the vehicle used to transport them to emergency departments and their Glasgow coma scale score (p < 0.05).Conclusion:Considering the young age of the child patients and over half of trauma happened at home,it is important to raise parents' awareness about the risky places and activities,which were likely to result in traumatic injuries for children.
2.Contribution of chromosomal aberrations to the pathogenesis of primary and secondary amenorrhea: A study from Western Iran
Azam AZIMI ; Matin HEIDARI ; Reza ALIBAKHSHI ; Sara HAMANI ; Negar SALIMI ; Parham NEJATI ; Nazanin JALILIAN
Clinical and Experimental Reproductive Medicine 2025;52(1):65-70
Objective:
Amenorrhea is an abnormal condition characterized by the absence of menstruation in women of reproductive age. According to the World Health Organization, amenorrhea ranks as the sixth leading cause of female infertility. Approximately 2% to 5% of women of reproductive age experience amenorrhea, which can be classified as primary amenorrhea (PA) or secondary amenorrhea (SA). Several studies have named chromosomal abnormalities among the main causes of amenorrhea, though the prevalence of these abnormalities may differ across populations. The objective of this study was to ascertain the frequency and types of chromosomal abnormalities in women with amenorrhea in Kermanshah Province, Iran.
Methods:
This retrospective study included patients with PA and SA who underwent standard cytogenetic analysis. We also conducted a review of the literature on chromosomal abnormalities and their prevalence in SA.
Results:
Among the 137 cases of PA in this study, 22% exhibited chromosomal abnormalities. Numerical changes were the most common finding (46.6%) in this group, including 45,X, mosaic, and 47,XXX karyotypes. These were followed by the 46,XY karyotype (40%). Of the 51 cases of SA that received chromosomal analysis, abnormalities were identified in only one case. Additionally, our review of the literature revealed that chromosomal aberrations are responsible for 7% of SA cases globally.
Conclusion
In this study, we successfully characterized the cytogenetic causes of PA and SA in a substantial population from Kermanshah Province, Iran.
3.Contribution of chromosomal aberrations to the pathogenesis of primary and secondary amenorrhea: A study from Western Iran
Azam AZIMI ; Matin HEIDARI ; Reza ALIBAKHSHI ; Sara HAMANI ; Negar SALIMI ; Parham NEJATI ; Nazanin JALILIAN
Clinical and Experimental Reproductive Medicine 2025;52(1):65-70
Objective:
Amenorrhea is an abnormal condition characterized by the absence of menstruation in women of reproductive age. According to the World Health Organization, amenorrhea ranks as the sixth leading cause of female infertility. Approximately 2% to 5% of women of reproductive age experience amenorrhea, which can be classified as primary amenorrhea (PA) or secondary amenorrhea (SA). Several studies have named chromosomal abnormalities among the main causes of amenorrhea, though the prevalence of these abnormalities may differ across populations. The objective of this study was to ascertain the frequency and types of chromosomal abnormalities in women with amenorrhea in Kermanshah Province, Iran.
Methods:
This retrospective study included patients with PA and SA who underwent standard cytogenetic analysis. We also conducted a review of the literature on chromosomal abnormalities and their prevalence in SA.
Results:
Among the 137 cases of PA in this study, 22% exhibited chromosomal abnormalities. Numerical changes were the most common finding (46.6%) in this group, including 45,X, mosaic, and 47,XXX karyotypes. These were followed by the 46,XY karyotype (40%). Of the 51 cases of SA that received chromosomal analysis, abnormalities were identified in only one case. Additionally, our review of the literature revealed that chromosomal aberrations are responsible for 7% of SA cases globally.
Conclusion
In this study, we successfully characterized the cytogenetic causes of PA and SA in a substantial population from Kermanshah Province, Iran.
4.Contribution of chromosomal aberrations to the pathogenesis of primary and secondary amenorrhea: A study from Western Iran
Azam AZIMI ; Matin HEIDARI ; Reza ALIBAKHSHI ; Sara HAMANI ; Negar SALIMI ; Parham NEJATI ; Nazanin JALILIAN
Clinical and Experimental Reproductive Medicine 2025;52(1):65-70
Objective:
Amenorrhea is an abnormal condition characterized by the absence of menstruation in women of reproductive age. According to the World Health Organization, amenorrhea ranks as the sixth leading cause of female infertility. Approximately 2% to 5% of women of reproductive age experience amenorrhea, which can be classified as primary amenorrhea (PA) or secondary amenorrhea (SA). Several studies have named chromosomal abnormalities among the main causes of amenorrhea, though the prevalence of these abnormalities may differ across populations. The objective of this study was to ascertain the frequency and types of chromosomal abnormalities in women with amenorrhea in Kermanshah Province, Iran.
Methods:
This retrospective study included patients with PA and SA who underwent standard cytogenetic analysis. We also conducted a review of the literature on chromosomal abnormalities and their prevalence in SA.
Results:
Among the 137 cases of PA in this study, 22% exhibited chromosomal abnormalities. Numerical changes were the most common finding (46.6%) in this group, including 45,X, mosaic, and 47,XXX karyotypes. These were followed by the 46,XY karyotype (40%). Of the 51 cases of SA that received chromosomal analysis, abnormalities were identified in only one case. Additionally, our review of the literature revealed that chromosomal aberrations are responsible for 7% of SA cases globally.
Conclusion
In this study, we successfully characterized the cytogenetic causes of PA and SA in a substantial population from Kermanshah Province, Iran.
5. Prognosis in children with traumatic injuries referring to the emergency department
Farzad AKBARYAN ; Hojjat DERAKHSHANFAR ; Kamran HEIDARI ; Ali VAFAEI ; Somaieh MATIN
Chinese Journal of Traumatology 2019;22(6):323-327