1.Case of Pseudoaneurysm Mimicking a Soft Tissue Sarcoma: A Diagnostic Pitfall
Sandeep Albert ; Sanju Daniel ; Mohamad Gouse ; Vinu Mathew Cherian
Malaysian Journal of Medical Sciences 2015;22(2):61-64
Pseudoaneurysms represent a pulsating encapsulated hematoma in communication with the lumen of a ruptured vessel. We present a 33-year-old male with a pseudoaneurysm of the profunda femoris artery. At presentation and on further evaluation, he was diagnosed with a possible soft tissue sarcoma of the distal thigh. Catastrophic haemorrhage occurred at the time of a planned, elective open biopsy. This case report emphasises the importance of considering pseudoaneurysm as a crucial differential diagnosis in atypical swellings and scrutinising all suspected soft tissue tumours with a contrast study or a Doppler ultrasound.
2.Preoperative determination of tibial nail length: An anthropometric study.
Renjit-Thomas ISSAC ; Hitesh GOPALAN ; Mathew ABRAHAM ; Cherian JOHN ; Sujith-Mathew ISSAC ; Diju JACOB
Chinese Journal of Traumatology 2016;19(3):151-155
OBJECTIVETo assess the correlation between five anthropometric parameters and the distance from tibial tuberosity to medial malleolus in 100 volunteers.
METHODSSix anthropometric parameters were measured in 50 male and 50 female medical students using a metallic scale: medial knee joint line to ankle joint line (K-A), medial knee joint line to medial malleolus (K-MM), tibial tuberosity to ankle joint (TT-A), tibial tuberosity to medial malleolus (TT- MM), olecranon to 5th metacarpal head (O-MH) and body height (BH). Nail size predicted based upon TT-MM measurement was chosen as ideal nail size. A constant was derived for each of the six anthropometric parameters which was either added or subtracted to each measurement to derive nail size. A regression equation was applied to BH measurements. Nail sizes calculated were compared with that obtained from TT-MM measurement and accuracy was evaluated. Accuracy of O-MH and BH regression equations recommended by other authors were calculated in our data.
RESULTSAdding 11 mm to TT-A distance had highest accuracy (81%) and correlation (0.966) in predicting nails correctly. Subtracting 33 mm from K-MM measurement and 25 mm from K-A distance derived accurate sizes in 69% and 76% respectively. Adding 6 mm to O-MH distance had a poor accuracy of 51%. Nail size prediction based upon body height regression equation derived correct nail sizes in only 34% of the cases. Regression equation analysis by other authors based on O-MH and BH distances yielded correct sizes in 11% and 5% of the cases respectively.
CONCLUSIONTT-A, K-A and K-MM measurements can be used simultaneously to increase accuracy of nail size prediction. This method would be helpful in determining nail size preoperatively especially when one anatomic landmark is difficult to palpate.
Adult ; Anthropometry ; Body Height ; Bone Nails ; Female ; Fracture Fixation, Intramedullary ; instrumentation ; Humans ; Male ; Preoperative Care ; Tibial Fractures ; surgery
3.Nonoperatively treated infraglenoid tubercle avulsion.
Renjit Thomas ISSAC ; Hitesh GOPALAN ; Cherian JOHN ; Mathew ABRAHAM ; Sujith Mathew ISSAC
Chinese Journal of Traumatology 2014;17(5):301-304
Infraglenoid tubercle avulsion fractures are extremely rare injuries. We report a 38-year-old male with glenoid cavity fracture and infraglenoid tubercle avulsion of the left shoulder following a fall from bike. He refused surgery and was treated nonoperatively. Follow-up radiography and CT at 18 months revealed a malunited infraglenoid tubercle with signs of early glenohumeral osteoarthritis. He did not have shoulder instability or pain and had a fair-good functional outcome. There are no previously published data on the anatomic outcome of nonoperatively treated displaced infraglenoid tubercle avulsion fractures based on CT.
Adult
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Bicycling
;
injuries
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Humans
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Male
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Scapula
;
injuries
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Shoulder Fractures
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diagnostic imaging
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therapy
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Tomography, X-Ray Computed
4.REtrospective Multicenter INdian Study of Derivo Embolization Device (REMIND): Periprocedural Safety
Niranjan Prakash MAHAJAN ; Mudasir MUSHTAQ ; Amit BHATTI ; Sukalyan PURKAYASTHA ; Nitin DANGE ; Mathew CHERIAN ; Vipul GUPTA ; Vikram HUDED
Neurointervention 2021;16(3):232-239
Purpose:
The treatment of aneurysms with characteristics such as complex morphology, fusiform, blister-like, wide neck, or large size has been revolutionized with the introduction of flow diverters. Though flow diverters have several advantages over coiling, they also have certain important disadvantages such as the lack of immediate protection against rupture, the risk of ischemic stroke, the need for antiplatelet therapy, and long latency for complete effect. The Derivo Embolization Device (DED) is a second-generation self-expanding device that is claimed to be less thrombogenic than conventional devices. We retrospectively evaluated the periprocedural safety and risks associated with the DED across 5 centers in India.
Materials and Methods:
This is a multicentric, retrospective, observational study of DED, conducted at 5 high volume endovascular therapy centers in India from May 2018 to June 2020. Periprocedural demographic, clinical, and angiographic data were collected from a retrospective review of patient charts.
Results:
A total of 96 patients, including 56 (58.3%) females, aged between 16–80 years (60±12.7 years) harboring 106 aneurysms were studied. Seven (7.3%) were noted to harbor multiple aneurysms: 6 had 3 aneurysms each, while 1 patient had 5 aneurysms. The following aneurysm characteristics were noted: average size, 9.8±8.2 mm; average neck size, 6.9±8.5 mm; wide-necked (>4 mm), 63 (59.4%); giant (>25 mm), 8 (7.5%); and anterior circulation location, 98 (92.5%). Eighteen (17%) of these were ruptured. Additional balloon angioplasty was performed in 5 (5.2%) patients. Intraprocedural problems were encountered in 3 (3.1%), of which only 1 had clinical implications, the device fish-mouthing with stent thrombosis resulting in a malignant middle cerebral artery territory infarction. The modified Rankin scale at 3 months was worse in 1 patient.
Conclusion
DED is a newer generation flow diverter stent with a low periprocedural complication rate.
5.Tenecteplase versus alteplase (TENVALT): A study comparing two thrombolytic agents in acute ischemic stroke
Kaushik Sundar ; Lomesh Bhirud ; Ajay Panwar ; Jerin Jose Cherian ; Eldho Mathew Paul ; Gigy Varkey Kuruttukulam
Neurology Asia 2019;24(3):203-208
Background & Objective: The Indian data comparing the efficacy and safety outcomes of tenecteplase
and alteplase in acute ischemic stroke is scarce. We aimed to compare the outcomes of two agents in
an Indian population. Methods: TENVALT study was a single centre, retrospective study. Patients aged
18 years or older with acute ischemic stroke were included in this study if they presented within 3
hours of symptom onset and had a deficit with National Institute of Health Stroke Scale (NIHSS) score
> 4, had a modified Rankin score (mRS) of 2 or less before the stroke onset and had no evidence of
hemorrhage on non-contrast computed tomography of brain. A good functional recovery (mRS score
of 0-2) at the end of three months was defined as the primary efficacy outcome. The development of
symptomatic intracerebral hemorrhage was considered as the primary safety outcome. Results: A total
of 120 patients (alteplase, n=65; tenecteplase, n=55) underwent stroke thrombolysis during this study.
The mean age of the presentation in tenecteplase group was 66.6 years and in alteplase group was
62.5 years. Most of the study subjects were males in both the groups (tenecteplase, 78.2%; alteplase,
61.5%). Hypertension was the most common comorbidity in both the groups (tenecteplase, 67.3%;
alteplase, 76.9%). Median mRS score at 3 months of follow up was 2 in tenecteplase and 1 in alteplase group; however, the difference between the total number of patients having good functional recovery (mRS 0-2) in the two groups was not statistically significant (tenecteplase 74.5 vs alteplase 87.7%, P=0.09). The total number of patients who had symptomatic intracranial hemorrhage was comparable between the two groups (tenecteplase, 5.5%; alteplase, 6.2%). Conclusion: Tenecteplase appears to be an efficacious alternative to alteplase for stroke thrombolysis and may be better suited to developing countries considering its low cost and ease of administration.