1.Efficacy of Fentanyl Buccal Tablets for Patients Who Cannot Retain at the Above a Rear Molar between the Upper Cheek and Gum
Daisuke TAKEI ; Kazumasa MATSUZAKA ; Kinomi YOMIYA ; Masumi NAKAMURA
Palliative Care Research 2020;15(3):239-243
Fentanyl buccal tablets place the tablet at the buccal site (above a rear molar, between the upper cheek and gum) and wait until it dissolves, but some patients may not be able to retain it due to defects of the maxillary molars. The aim of this study was to evaluate the effectiveness and safety of fentanyl buccal tablets when they were used outside the buccal site. Seven patients were treated with fentanyl buccal tablets outside the buccal site. For each of 5 episodes in which effective dose was identified, were investigated to average pain intensity assessed on a 0 to 10 numerical rating scale at 30 min postadministration and reduction in pain intensity of more than 33%. Pain intensity significantly decreased at 30 min postadministration in 5 patients with effective doses identified (p<0.001). In 92.0% of episodes treated, there was a reduction in pain intensity of more than 33%. Adverse events were somnolence and nausea with mild. However, these effects did not result in discontinuation of medication. Our findings suggested that fentanyl buccal tablets can be used effectively and safely even when patients used outside the buccal site.
2.The dynamic movement for global health ─Hot topics on migrants and refugee health!, Supports for refugees─call for empowerment, Living conditions of refugees in Japan, Tragedy of Afghanistan: ─what the international society should do now?─, The role of international NGOs in the health sector in humanitarian crises: experiences of supporting the Thai-Myanmar border in chronic emergency situations, National Institute of Population and Social Security Research/Committee for Migration and Health, JAIH
Azusa IWAMOTO ; Yasuhide NAKAMURA ; Yukie KAN ; Khaled RESHAD ; Jun KOBAYASHI ; Yuka MAEKAWA ; Yoko FUCHIGAMI ; Masumi TANAKA ; Aya TABATA ; Tomoko KAMIYA ; Chika SATO ; Koichi IKEMURA ; Ryoko TOYAMA ; Miwa SAWABE ; Tadashi TAKEUCHI ; Toshiyuki WATANABE ; Tsubasa NAKAZATO ; Hiromi NISHIO ; Nanae ARITAKA ; Reiko HAYASHI
Journal of International Health 2022;37(3):113-131