1.Artificial intelligence technology in cardiac auscultation screening for congenital heart disease: present and future.
Weize XU ; Kai YU ; Jiajun XU ; Jingjing YE ; Haomin LI ; Qiang SHU
Journal of Zhejiang University. Medical sciences 2020;49(5):548-555
The electronic stethoscope combined with artificial intelligence (AI) technology has realized the digital acquisition of heart sounds and intelligent identification of congenital heart disease, which provides objective basis for heart sound auscultation and improves the accuracy of congenital heart disease diagnosis. At the present stage, the AI based cardiac auscultation technique mainly focuses on the research of AI algorithms, and the researchers have designed and summarized a variety of effective algorithms based on the characteristics of cardiac audio data, among which the mel-frequency cepstral coefficients (MFCC) is the most effective one, and widely used in the cardiac auscultation. However, the current cardiac sound analysis techniques are based on specific data sets, and have not been validated in clinic, so the performance of algorithms need to be further verified. The lack of heart sound data, especially the high-quality, standardized, publicly available heart sound database with disease labeling, further restricts the development of heart sound diagnostic analysis and its application in screening. Therefore, expert consensus is necessary in establishing an authoritative heart sound database and standardizing the heart sound auscultation screening process for congenital heart disease. This paper provides an overview of the research and application status of auscultation algorithm and hardware equipment based on AI in auscultation screening of congenital heart disease, and puts forward the problems to be solved in clinical application of AI auscultation screening technology.
Algorithms
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Artificial Intelligence
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Heart Auscultation/trends*
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Heart Defects, Congenital/diagnosis*
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Humans
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Mass Screening/methods*
2.Population Screening for Colorectal Cancer Means Getting FIT: The Past, Present, and Future of Colorectal Cancer Screening Using the Fecal Immunochemical Test for Hemoglobin (FIT).
James E ALLISON ; Callum G FRASER ; Stephen P HALLORAN ; Graeme P YOUNG
Gut and Liver 2014;8(2):117-130
Fecal immunochemical tests for hemoglobin (FIT) are changing the manner in which colorectal cancer (CRC) is screened. Although these tests are being performed worldwide, why is this test different from its predecessors? What evidence supports its adoption? How can this evidence best be used? This review addresses these questions and provides an understanding of FIT theory and practices to expedite international efforts to implement the use of FIT in CRC screening.
Colorectal Neoplasms/*diagnosis
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Early Detection of Cancer/methods/trends
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Feces/*chemistry
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Forecasting
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Global Health
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Hemoglobins/*analysis
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Humans
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Immunochemistry
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Mass Screening/methods/trends
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Occult Blood
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Sensitivity and Specificity