1.Kampo Medicine Treatment for Various Chronic Treatment-resistant Skin Diseases except for Atopic Dermatitis—Research of their Background for the Reason Why They are so Resistant—
Masamitsu ISHII ; Manabu MAEDA ; Michiyo SAKURAI ; Yoshio HASHIMOTO ; Tetsuo SANDA ; Teruo KUROKAWA ;
Kampo Medicine 2011;62(2):241-276
2.Utility of Dermoscopy before and after Laser Irradiation in Port Wine Stains.
Makiko SHIRAKAWA ; Toshiyuki OZAWA ; Satoki WAKAMI ; Masamitsu ISHII ; Teruichi HARADA
Annals of Dermatology 2012;24(1):7-10
BACKGROUND: Port wine stains (PWSs) are commonly treated with pulsed dye laser (PDL) as a standard therapy. However, it is not easy to predict the minimal effective dose in the first treatment session. OBJECTIVE: The aim of this study was to assess whether dermoscopic findings before and after laser irradiation corresponded with the clinical improvement of PWS in patients undergoing PDL therapy. METHODS: Seven untreated PWSs in 6 patients (a male and 5 females), who presented to our hospital between May 2008 to January 2010, were assessed in this study. The mean age was 36.3 years, ranging from 14 to 57 years. A PDL with a wavelength of 585 nm and a spot size of 7 mm was used. Before and after test irradiation, patients underwent dermoscopy and clinical photography, and we assessed whether the dermoscopic findings corresponded with clinical improvement after 3 months. RESULTS: There were no obvious differences observed in the clinical photographs between each test level immediately after irradiation. However, dermoscopic photographs showed differences as the irradiated energy increased. These changes corresponded to the clinical improvement after 3 months. CONCLUSION: Our study indicates that the minimal effective fluence can be predicted by observing dermoscopic change immediately after irradiation. We think that examining the dermoscopic findings immediately after irradiation allows the laser surgeon to predict the minimal effective fluence and this prevents adverse effects of the skin.
Dermoscopy
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Humans
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Lasers, Dye
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Male
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Photography
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Port-Wine Stain
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Skin