2.Usefulness of Cell Blocks From Forceps and Brush Washing Fluid in Bronchoscopy
Mamiko KURIYAMA ; Makoto NAKAO ; Ryosuke KINOSHITA ; Hiroko KIYOTOSHI ; Masahiro SUGIHARA ; Norihisa TAKEDA ; Miki FUKAI ; Kazuyoshi YAMADA ; Masateru KITAJIMA ; Takuji TSUYUKI ; Hideki MURAMATSU
Journal of the Japanese Association of Rural Medicine 2023;72(4):307-313
Background: Cell blocks (CBs) from pleural fluid are frequently used in the practice of respiratory medicine, but there have been few reports on the use of CBs from forceps and brush washing fluid in bronchoscopy for pathological diagnosis. We retrospectively analyzed the usefulness of CBs from forceps and brush washing fluid. Patients and Methods: Patients who underwent bronchoscopy and had CBs made from forceps and brush washing fluid in bronchoscopy at our institution between June 2016 and May 2021 were included. Cases in which additional information was obtained from CBs were reviewed in detail. Results: In total, 138 patients had CBs made from forceps and brush washing fluid in bronchoscopy during the study period. EBUS-GS (endobronchial ultrasound-guide sheath) was used for 102 of these patients. The final diagnosis was lung cancer in 114 cases, infection disease in 10 cases, metastatic lung tumor in 8 cases, lymphoproliferative disease in 2 cases, sarcoidosis in 1 case, and organizing pneumonia in 1 case. There were 13 cases with additional information obtained from CBs, all of which were cases of malignant tumors. Conclusions: CBs from forceps and brush washing fluid in bronchoscopy were useful for pathological diagnosis in some cases.
3.Association between Asian dust exposure and respiratory function in children with bronchial asthma in Nagasaki Prefecture, Japan.
Takahiro NAKAMURA ; Yuji NISHIWAKI ; Kunio HASHIMOTO ; Ayano TAKEUCHI ; Tasuku KITAJIMA ; Kazuhiro KOMORI ; Kasumi TASHIRO ; Hideki HASUNUMA ; Kayo UEDA ; Atsushi SHIMIZU ; Hiroshi ODAJIMA ; Hiroyuki MORIUCHI ; Masahiro HASHIZUME
Environmental Health and Preventive Medicine 2020;25(1):8-8
BACKGROUND:
Studies on the adverse effects of Asian dust (AD) on respiratory function in children are scarce. The objective of this study was to examine the association between AD and respiratory function by measuring peak expiratory flow rates (PEFRs) in asthmatic children.
METHODS:
The study was carried out from March to May from 2014 through 2016. One hundred ten children with bronchial asthma were recruited from four hospitals in the Goto Islands and south Nagasaki area in Nagasaki prefecture. The parents were asked to record their children's PEFRs every morning/evening and clinical symptoms in an asthma diary. AD was assessed from light detection and ranging data, and a linear mixed-effects model was used to estimate the effects of AD on daily PEFR. Time-stratified case-crossover analyses were performed to examine the association between AD and asthma attacks defined by reduction levels in PEFR.
RESULTS:
AD was detected on 11 days in the Goto Islands, and on 23 days in the south Nagasaki area. After adjusting for age, sex, temperature, and daily oxidants, we found a consistent association between AD and a 1.1% to 1.7% decrease in PEFR in the mornings and a 0.7% to 1.3% decrease in the evenings at a lag of 0 to 5 days. AD was not associated with the number of asthma attacks, respiratory symptoms, or other symptoms at any lag days examined.
CONCLUSIONS
Exposure to AD was associated with reduced PEFR, although the effects were not large enough to induce clinically apparent symptoms, in clinically well-controlled asthmatic children.