1.Evaluation of Myocardial Protection and Postoperative Early Diastolic Function in Aortic Stenosis with Severe Concentric Hypertrophy.
Masafumi NATSUAKI ; Tsuyoshi ITOH ; Masaru YOSHIKAI ; Kouzou NAITOH ; Yoshihiro NAKAYAMA ; Tetsuya UENO ; Naoki MINATO ; Masahito SAKAI
Japanese Journal of Cardiovascular Surgery 1993;22(5):387-393
Postoperative cardiac function and the occurrence of arrythmia depend upon myocardial protection during open heart surgery in severe concentric hypertrophy. The effect of myocardial protection was evaluated in terms of several released cardiac enzymes before and after reperfusion, and postoperative left ventricular (LV) cardiac function from cardiac pool scintigram in 21 cases with aortic stenosis (AS Group). These data were compared with 20 cases with aortic regurgitation (AR Group). Heart weight and aortic cross-clamping time were not significantly different in these two groups. The enzymatic values in peak total creatine-kinase (CK) and peak CK-MB fraction were higher in the AS group than in the AR group, and peak GOT was significantly elevated in the AS group (peak GOT: 93±32 in AS group, 64±17IU/l in the AR group, p<0.01). Among the cases in the AS group, six cases with LV small cavity (LVDd<4cm) and severe concentric hypertrophy were associated with high values of released enzyme and the occurrence of ventricular arrythmia. Postoperative cardiac function was estimated from both systolic parameters such as LV ejection fraction (LVEF) or peak ejection rate (PER) and diastolic parameters such as peak filling rate (PFR) or early diastolic filling rate (1/3PFR). Postoperative LVEF and PER improved to normal control levels in the AS group with preoperatively depressed systolic function, although values were decreased in the AR group with impaired systolic function. The postoperative early diastolic peak filling rate did not recover to control levels in the AS group as well as the AR group, and was impaired in the AS group with severe concentric hypertrophy due to elevated chamber stiffness and the delay of time to peak filling rate. In severe concentric hypertrophy, we used several techniques for myocardial protection of terminal blood cardioplegia, and gradually increased reperfusion pressure and LV venting after reperfusion. Late results revealed a good clinical course in all 21 cases except for the occurrence of arrythmia in three.
2.A Case Report of Double False Aneurysms Associated with a Penetrating Atherosclerotic Ulcer.
Kazuyoshi Doi ; Tuyoshi Itoh ; Masafumi Natsuaki ; Hiroaki Norita ; Kouzou Naito ; Masahito Sakai ; Keiji Kamohara ; Nobuhisa Yonemitsu
Japanese Journal of Cardiovascular Surgery 1998;27(6):372-375
A 72-year-old man was admitted with an abnormal shadow on chest X-ray. Chest CT and aortography showed double saccular aneurysms at the aortic arch and the descending thoracic aorta. Three-dimensional CT was useful to detect the association between the arch aneurysm and neck vessels. Graft replacement, from the distal arch to the descending thoracic aorta, was performed by the lateral approach with hypothermic arrest and open proximal method. The aorta had severe atherosclerotic changes and the intima was absent at the orifices of the aneurysms. Pathological examination showed the aneurysmal wall to be composed of fibrous tissue without medial components. These macroscopic and pathological findings of aneurysms corresponded with double pseudo-aneurysms originating from the penetrating atherosclerotic ulcer.
3.Results of Laminoplasty for Cervical Spondylotic Myelopathy.
Akihiko OKAMOTO ; Masafumi ISHIZUKI ; Yasushi ISOBE ; Norio SAITOH ; Masami TOMINAGA ; Hidehiko OZAWA ; Taisuke TANIZAWA ; Yasuo SUGATA ; Tomoyuki MOCHIZUKI ; Kenji HARA ; Kazuyuki SAKAI
Journal of the Japanese Association of Rural Medicine 2001;49(5):729-732
[Follow-up studies were made of 35 patient who underwent laminoplasty for cervical spondylotic myelopathy for 22 monthoon averages]
The conditions of 35 patients were observed consecutively after laminoplasty.
The mean JOA scores were improved from 8.7 to 12.5. Postoperative JOA scores correlated with preoperarive JOA scores (r=0.60, p<0.01) and ages at the time of the operation (r=-0.45, p<0.01). The period from the onset of the disease to the operation and the vertebral canal diameters didnot [No significant correlation who found between- and-] influence the operative results of the operation.
4.Clinical and MRI Characteristics of Uterine Cervical Adenocarcinoma: Its Variants and Mimics
Tsukasa SAIDA ; Akiko SAKATA ; Yumiko Oishi TANAKA ; Hiroyuki OCHI ; Toshitaka ISHIGURO ; Masafumi SAKAI ; Hiroaki TAKAHASHI ; Toyomi SATOH ; Manabu MINAMI
Korean Journal of Radiology 2019;20(3):364-377
Adenocarcinoma currently accounts for 10–25% of all uterine cervical carcinomas and has a variety of histopathological subtypes. Among them, mucinous carcinoma gastric type is not associated with high-risk human papillomavirus (HPV) infection and a poor prognosis, while villoglandular carcinoma has an association with high-risk HPV infection and a good prognosis. They show relatively characteristic imaging findings which can be suggested by magnetic resonance imaging (MRI), though the former is sometimes difficult to be distinguished from lobular endocervical glandular hyperplasia. Various kinds of other tumors including squamous cell carcinoma should be also differentiated on MRI, while it is currently difficult to distinguish them on MRI, and HPV screening and pathological confirmation are usually necessary for definite diagnosis and further patient management.
Adenocarcinoma
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Adenocarcinoma, Mucinous
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Carcinoma, Squamous Cell
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Diagnosis
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Humans
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Hyperplasia
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Magnetic Resonance Imaging
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Mass Screening
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Prognosis
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Uterine Cervical Neoplasms
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Uterus