1.Differences in Hematological and Clinical Features Between Essential Thrombocythemia Cases With JAK2- or CALR-Mutations.
Yoko KUBUKI ; Kotaro SHIDE ; Takuro KAMEDA ; Takumi YAMAJI ; Masaaki SEKINE ; Ayako KAMIUNTEN ; Keiichi AKIZUKI ; Haruko SHIMODA ; Yuki TAHIRA ; Kenichi NAKAMURA ; Hiroo ABE ; Tadashi MIIKE ; Hisayoshi IWAKIRI ; Yoshihiro TAHARA ; Mitsue SUETA ; Kanna HASHIMOTO ; Shojiro YAMAMOTO ; Satoru HASUIKE ; Tomonori HIDAKA ; Kenji NAGATA ; Akira KITANAKA ; Kazuya SHIMODA
Annals of Laboratory Medicine 2017;37(2):159-161
No abstract available.
Adolescent
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Adult
;
Age Factors
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Aged
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Aged, 80 and over
;
Amino Acid Sequence
;
Calreticulin/*genetics
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Child
;
DNA/chemistry/genetics/metabolism
;
Exons
;
Female
;
Humans
;
Janus Kinase 2/*genetics
;
Male
;
Middle Aged
;
Molecular Sequence Data
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Polymorphism, Single Nucleotide
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Receptors, Thrombopoietin/genetics
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Sequence Analysis, DNA
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Sex Factors
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Thrombocythemia, Essential/*diagnosis/genetics
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Young Adult
2.Regional disparity of certified teaching hospitals on physicians' workload and wages, and popularity among medical students in Japan.
Yutaro IKKI ; Masaaki YAMADA ; Michikazu SEKINE
Environmental Health and Preventive Medicine 2021;26(1):75-75
BACKGROUND:
Regional disparities in the working conditions of medical doctors have not been fully assessed in Japan. We aimed to clarify these differences in hospital characteristics: doctors' workload, wages, and popularity among medical students by city population sizes.
METHODS:
We targeted 423 teaching hospitals certified by the Japanese Society of Internal Medicine and assessed the working conditions of physicians specializing in internal medicine. We calculated their workload (the annual number of discharged patients per physician) and retrieved data on junior residents' monthly wages from the Resinavi Book which is popular among medical students in Japan to know the teaching hospital's information and each hospital's website. Furthermore, we explored the interim matching rate of each hospital as its popularity among medical students. Next, we classified cities in which all hospitals were located into eight groups based on their population size and compared the characteristics of these hospitals using a one-way analysis of variance.
RESULTS:
The average workload was 110.3, while the average workload in hospitals located in most populated cities (≥ 2,000,000) was 88.4 (p < 0.05). The average monthly wage was 351,199 Japanese yen, while that in most populated cities was 305,635.1 Japanese yen. The average popularity (matching rate) was 101.9%, and the rate in most populated areas was 142.7%, which was significantly higher than in other areas.
CONCLUSIONS
Hospitals in most populated areas had significantly lower workloads and wages; however, they were more popular among medical students than those in other areas. This study was the first to quantify the regional disparities in physicians' working conditions in Japan, and such disparities need to be corrected.
Cities/statistics & numerical data*
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Geography
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Hospitals, Teaching/statistics & numerical data*
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Japan
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Physicians/statistics & numerical data*
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Population Density
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Salaries and Fringe Benefits/statistics & numerical data*
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Students, Medical/psychology*
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Workload/statistics & numerical data*
3.Associations of socioeconomic status and lifestyle factors with dental neglect of elementary school children: the MEXT Super Shokuiku School Project.
Yukiko ASAKA ; Michikazu SEKINE ; Masaaki YAMADA ; Takashi TATSUSE
Environmental Health and Preventive Medicine 2020;25(1):73-73
BACKGROUND:
Despite the fact that there are parents who do not take children with untreated dental caries to a dental clinic, few studies have been conducted to identify the responsible underlying social and family factors. The aim of this study was to investigate whether socioeconomic status and lifestyle factors are associated with dental neglect in elementary school children.
METHODS:
This study was conducted in 2016 with 1655 children from the Super Shokuiku School Project in Toyama. Using Breslow's seven health behaviors, the survey assessed: the grade, sex, and lifestyle of the children; parental internet and game use and lifestyle; socioeconomic status. The odds ratios (OR) and 95% confidence intervals (CIs) for having untreated dental caries were calculated using logistic regression analysis.
RESULTS:
Among the children participating, 152 (3.2%) had untreated dental caries. Among them, 53 (34.9%) had not been taken to a dental clinic despite the school dentist's advice. Dental neglect was significantly associated with children in higher grades (OR, 2.08; 95% CI, 1.14-3.78), father's Internet and game use ≥ 2 h/day (OR, 1.99; 95% CI, 1.02-3.88), not being affluent (OR, 2.78; 95% CI, 1.14-6.81), and non-engagement in afterschool activities (OR, 1.99; 95% CI, 1.10-3.62).
CONCLUSIONS
Socioeconomic status was the strongest factor associated with dental neglect despite the fact that the children's medical expenses are paid in full by the National Health Insurance in Toyama, Japan. Future studies should investigate what factors prevent parents of non-affluent families from taking their children to dental clinics and how they can be socially supported to access adequate medical care.
Age Factors
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Child
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Dental Caries/psychology*
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Female
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Humans
;
Japan/epidemiology*
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Life Style
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Male
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Prevalence
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Social Class
4.Association between lifestyle, parental smoke, socioeconomic status, and academic performance in Japanese elementary school children: the Super Diet Education Project.
Masaaki YAMADA ; Michikazu SEKINE ; Takashi TATSUSE ; Yukiko ASAKA
Environmental Health and Preventive Medicine 2019;24(1):22-22
BACKGROUND:
Health and education are closely linked. However, few studies have explored the correlates of children's academic performance in Japan. We aimed to investigate comprehensively the associations of low academic performance among school children with lifestyles, parental smoke, and socioeconomic status.
METHODS:
In 2016, children aged 6 to 13 years from the Super Diet Education School Project were surveyed using questionnaires. The survey explored the lifestyles and subjective academic performance of 1663 children and asked their parents about parental smoke and subjective socioeconomic status. Academic performance and socioeconomic status were divided into three levels. Then, we defined subjective academic performance in the lower two levels as low academic performance. The odds ratios (OR) were analyzed by logistic regression analysis.
RESULTS:
Among all participants, 299 (18.0%) children reported low academic performance. In general, low academic performance was significantly associated with late wakeup time (OR = 1.36 for 6:30 to < 7 a.m. and OR = 2.48 for ≥ 7 a.m.), screen time ≥ 2 h (OR = 1.35), studying at home < 1 h (OR = 1.82), paternal smoke (OR = 1.47), maternal smoke (OR = 1.87), and low socioeconomic status (OR = 1.48). Analyses stratified by grade showed stronger associations between academic performance and socioeconomic status in senior (OR = 1.62 for middle, OR = 1.52 for low in grades 4 to 6) than in junior children (OR = 1.15 for middle, OR = 1.38 for low in grades 1 to 3).
CONCLUSIONS
Children's lifestyles, parental smoke, and socioeconomic status were significantly associated with low academic performance among Japanese children. Parents and health care providers should take these findings into consideration to prevent children from having low academic performance.
Academic Performance
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statistics & numerical data
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Adolescent
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Child
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Cross-Sectional Studies
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Female
;
Health Surveys
;
Humans
;
Japan
;
Life Style
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Male
;
Parents
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Risk Factors
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School Health Services
;
statistics & numerical data
;
Smoke
;
adverse effects
;
Social Class
5.Social and family factors as determinants of exercise habits in Japanese elementary school children: a cross-sectional study from the Super Shokuiku School Project.
Satomi SAWA ; Michikazu SEKINE ; Masaaki YAMADA ; Yugo FUKAZAWA ; Yusuke HIRAKU
Environmental Health and Preventive Medicine 2020;25(1):54-54
BACKGROUND:
Many studies have already reported on the relationship between exercise habits and health among schoolchildren. However, few have examined social and/or family factors as determinants of exercise habits.
METHODS:
This study's participants included 1721 schoolchildren aged between 6 and 13 who were involved in the Super Shokuiku School Project in January 2016. A survey was conducted to assess gender, grade level, physical activity, lifestyle, overall health, enrichment of school life, social background, and parental lifestyles. Both dislike and lack of physical activity were used to measure poor exercise habits; correlates were analyzed using logistic regression.
RESULTS:
"Lack of close friends" had the strongest links with both dislike (adjusted odds ratio [OR] 5.30; 95% confidence interval [CI], 2.78-10.1) and lack of (adjusted OR 5.40; 95% CI, 2.81-10.4) physical activity. Further, children who engaged in long periods of screen time and lacked parental communication also tended to dislike and lack physical activity. Children with mothers who were unemployed (housewives) and had unhealthy lifestyles, as well as those with poor health, were also more likely to lack physical activity.
CONCLUSION
Social and family factors (e.g., having close friends) may be determinants of exercise habits among schoolchildren, independent of their own lifestyle factors. Although a longitudinal study is needed to determine causality, substantial attention may thus be required to these factors when promoting physical activity in children.
Adolescent
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Age Factors
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Child
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Cross-Sectional Studies
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Exercise
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psychology
;
Family Characteristics
;
Female
;
Habits
;
Humans
;
Japan
;
Life Style
;
Male
;
Sex Factors
;
Socioeconomic Factors
6.Prevalence of molar incisor hypomineralization and regional differences throughout Japan.
Masato SAITOH ; Yuki NAKAMURA ; Mika HANASAKI ; Issei SAITOH ; Yuji MURAI ; Yoshihito KURASHIGE ; Satoshi FUKUMOTO ; Yukiko ASAKA ; Masaaki YAMADA ; Michikazu SEKINE ; Haruaki HAYASAKI ; Shigenari KIMOTO
Environmental Health and Preventive Medicine 2018;23(1):55-55
BACKGROUND:
Molar incisor hypomineralization (MIH) frequently occurs in children worldwide. However, MIH prevalence throughout Japan has not yet been investigated. The purpose of this study was to clarify MIH prevalence rates and to consider potential regional differences throughout Japan.
METHODS:
A total of 4496 children aged 7-9 years throughout Japan were evaluated in this study. MIH prevalence rates among children were evaluated in eight regions throughout Japan. A child's residence was defined as the mother's residence during pregnancy. The localization of demarcated opacities and enamel breakdown was recorded on a standard code form using a guided record chart. Logistic regression analysis was used to evaluate whether MIH prevalence rates differed among age groups, sex, and regions.
RESULTS:
The overall prevalence of MIH in Japan was 19.8%. The prevalence of MIH was 14.0% in the Hokkaido region, 11.7% in the Tohoku region, 18.5% in the Kanto Shin-Etsu region, 19.3% in the Tokai Hokuriku region, 22.3% in the Kinki region, 19.8% in the Chugoku region, 28.1% in the Shikoku region, and 25.3% in the Kyushu region. These regional differences were statistically significant. Moreover, MIH prevalence rates decreased with age. No significant sex differences in MIH prevalence rates were demonstrated.
CONCLUSIONS
To our knowledge, this is the first MIH study carried out in several regions throughout Japan. Regional differences existed in MIH prevalence rates; particularly, MIH occurred more frequently in children residing in southwestern areas than those in northeastern areas of Japan.
Child
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Dental Enamel Hypoplasia
;
epidemiology
;
etiology
;
Female
;
Humans
;
Japan
;
epidemiology
;
Male
;
Prevalence