1.Shellfish/crustacean oral allergy syndrome among national service pre-enlistees in Singapore
Bernard Yu Hor THONG ; Shalini ARULANANDAM ; Sze Chin TAN ; Teck Choon TAN ; Grace Yin Lai CHAN ; Justina Wei Lyn TAN ; Mark Chong Wei YEOW ; Chwee Ying TANG ; Jinfeng HOU ; Khai Pang LEONG
Asia Pacific Allergy 2018;8(2):e18-
		                        		
		                        			
		                        			BACKGROUND: All Singaporean males undergo medical screening prior to compulsory military service. A history of possible food allergy may require referral to a specialist Allergy clinic to ensure that special dietary needs can be taken into account during field training and deployment. OBJECTIVE: To study the pattern of food allergy among pre-enlistees who were referred to a specialist allergy clinic to work up suspected food allergy. METHODS: Retrospective study of all pre-enlistees registered in the Clinical Immunology/Allergy New Case Registry referred to the Allergy Clinic from 1 August 2015 to 31 May 2016 for suspected food allergy. RESULTS: One hundred twenty pre-enlistees reporting food allergy symptoms other than rash alone were referred to the Allergy Clinic during the study period. Of these, 77 (64.2%) had food allergy. Among those with food allergy, mean age was 19.1 ± 1.5 years. They comprised predominantly Chinese (66.2%) and Malays (20.8%). The most commonly reported foods were shellfish/crustaceans (78%), peanut (15.6%), and egg (6.5%). Self-limiting oral allergy syndrome, OAS (itchy lips and throat with/without lip angioedema) was the most common manifestation (n = 33, 42.9%) followed by anaphylaxis (n = 23, 29.9%). Majority of OAS was from shellfish/crustacean (90.6%); of which shrimp (30.3%), crab (15.2%), and lobster (3.0%) were the most common. Mild childhood asthma (69.7%), allergic rhinitis (6.3%), and eczema (6.1%) were the most common atopic conditions among individuals with shellfish/crustacean OAS. This pattern was similar for shellfish/crustacean anaphylaxis. Skin prick tests were most commonly positive for shrimp (OAS 87.1% vs. anaphylaxis 100%), crab (OAS 95.8% vs. 90.9%), and lobster (OAS 91.7% vs. 63.6%). CONCLUSION: OAS to shellfish/crustaceans was more common than anaphylaxis among this study population of young males referred for food allergy symptoms other than rash alone.
		                        		
		                        		
		                        		
		                        			Anaphylaxis
		                        			;
		                        		
		                        			Arachis
		                        			;
		                        		
		                        			Asian Continental Ancestry Group
		                        			;
		                        		
		                        			Asthma
		                        			;
		                        		
		                        			Eczema
		                        			;
		                        		
		                        			Exanthema
		                        			;
		                        		
		                        			Food Hypersensitivity
		                        			;
		                        		
		                        			Humans
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		                        			Hypersensitivity
		                        			;
		                        		
		                        			Lip
		                        			;
		                        		
		                        			Male
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		                        			Mass Screening
		                        			;
		                        		
		                        			Military Personnel
		                        			;
		                        		
		                        			Ovum
		                        			;
		                        		
		                        			Pharynx
		                        			;
		                        		
		                        			Referral and Consultation
		                        			;
		                        		
		                        			Retrospective Studies
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		                        			Rhinitis, Allergic
		                        			;
		                        		
		                        			Shellfish
		                        			;
		                        		
		                        			Singapore
		                        			;
		                        		
		                        			Skin
		                        			;
		                        		
		                        			Specialization
		                        			
		                        		
		                        	
 
            
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