1.Asthma Management in the time of COVID-19
Nicole Yu-Fang Sieow ; Mariko Siyue Koh
The Singapore Family Physician 2020;46(4):66-71
Asthma is a chronic inflammatory airway disease which results in variable expiratory airflow limitation. While there is currently no evidence that asthma increases the risk of COVID-19 or its severity of illness, new data emerges daily. This article outlines the recommendations by Global Initiative for Asthma (GINA), British Thoracic Society (BTS) and National Asthma Council Australia (NACA) which are relevant to primary care management of asthma in light of the COVID-19 pandemic.
2.Endobronchial ultrasound-guided tranbronchial needle aspiration (EBUS-TBNA) in the diagnosis and staging of lung cancer.
Devanand ANANTHAM ; Mariko Siyue KOH
Chinese Journal of Lung Cancer 2010;13(5):418-423
Biopsy, Fine-Needle
;
methods
;
Bronchi
;
diagnostic imaging
;
pathology
;
Endosonography
;
methods
;
Humans
;
Lung Neoplasms
;
diagnosis
;
pathology
;
Mediastinum
;
pathology
;
Neoplasm Staging
3.Zero Tolerance Towards Asthma Deaths in Singapore: Role of the Family Doctor
Hui Zhong CHAI ; Mariko Siyue Koh
The Singapore Family Physician 2018;44(4):10-13
Asthma is a common chronic respiratory disease in Singapore and it is the primary cause of chronic respiratory disease burden in childhood and early adulthood. Despite having one of the best healthcare systems in the world, our asthma mortality rates are several folds higher than other first world countries. Most asthma deaths are preventable. We illustrate a case of fatal asthma and highlight some learning points from this case.
4.The AsthmaID Tool in Singapore: Four Simple Questions to Detect Patients in need of an Asthma Review by a Specialist
Bennett Ong ; Mariko Siyue Koh ; Maarten Beekman ; Julie Hales ; Tze Lee Tan
The Singapore Family Physician 2021;47(1):50-53
A rising prevalence of asthma in Singapore translates to a more considerable patient care burden for general practitioners. Along with diagnosing and managing the treatment of asthma, general practitioners must recognise when referral to a respiratory specialist
is necessary. Although mild to moderate asthma is generally manageable in the primary care setting, patients with poorly controlled, difficult-to-treat, or severe asthma may benefit from referral to a specialist. Currently, many of these patients are not receiving optimal care, which places them at risk of asthma exacerbations and unnecessary systemic corticosteroid use. AsthmaID was developed as a tool for general practitioners to identify patients with asthma for whom a specialist evaluation could help improve asthma symptom control and optimise treatment strategies. Using four questions developed by asthma experts and rooted in the Global Initiative for Asthma report, AsthmaID quickly identifies patients who may benefit from a specialist referral without requiring additional patient assessments or testing modalities. Implementation of AsthmaID in clinical practice has the potential to transform the patient care pathway, thereby improving the quality of care for patients with asthma.
5.Managing adult asthma during the COVID-19 pandemic: A 2022 review and current recommendations.
Kheng Yong ONG ; Pei Yee TIEW ; Mariko Siyue KOH
Annals of the Academy of Medicine, Singapore 2022;51(10):637-647
INTRODUCTION:
This review aims to examine asthma management during the COVID-19 pandemic.
METHOD:
Relevant recommendations and articles were identified by respiratory professional societies and PubMed search using the terms "asthma" and "COVID-19", and examined for relevance and inclusion in this study.
RESULTS:
Recommendations for the management of asthma have remained similar but are now supported by new evidence between the years 2020 and 2022. Patients with well-controlled, mild-to-moderate asthma are unlikely to be at increased risk of acquiring COVID-19 or having worse outcomes from COVID-19. All asthma patients should receive COVID-19 vaccination. Spirometry can be performed with the usual strict infection control procedures unless there is a suspicion of COVID-19. Mask-wearing and other health measures remain important for asthma patients.
CONCLUSION
While previous recommendations were largely based on expert opinion, the tremendous amount of literature published since the pandemic first emerged 2 years ago has helped guide respiratory professional bodies to update their recommendations. This study provides a timely review of the various recommendations and can be used to guide healthcare professionals in managing asthma patients, as the world prepares for a future with COVID-19 becoming endemic. The long-term consequences of COVID-19 infection in asthma patients and the ripple effects of COVID-19 remain uncertain and deserve ongoing study.
Adult
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Humans
;
COVID-19
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Pandemics/prevention & control*
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COVID-19 Vaccines
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Asthma/epidemiology*
;
Infection Control
7.Heterogeneity of non-cystic-fibrosis bronchiectasis in multiethnic Singapore: A prospective cohort study at a tertiary pulmonology centre.
Si Ling YOUNG ; Youxin PUAN ; Si Yuan CHEW ; Salahudeen Mohamed HAJA MOHIDEEN ; Pei Yee TIEW ; Gan Liang TAN ; Mariko Siyue KOH ; Ken Cheah Hooi LEE
Annals of the Academy of Medicine, Singapore 2021;50(7):556-565
INTRODUCTION:
Non-cystic fibrosis bronchiectasis (NCFB) is a highly heterogenous disease. We describe the clinical characteristics of NCFB patients and evaluate the performance of Bronchiectasis Severity Index (BSI) in predicting mortality.
METHODS:
Patients attending the bronchiectasis clinic between August 2015 and April 2020 with radiologically proven bronchiectasis on computed tomography were recruited. Clinical characteristics, spirometry, radiology, microbiology and clinical course over a median period of 2.4 years is presented.
RESULTS:
A total of 168 patients were enrolled in this prospective cohort study. They were predominantly women (67.8%), Chinese (87.5%) and never-smokers (76.9%). Median age of diagnosis was 64 years (interquartile range 56-71) and the most common aetiology was "idiopathic" bronchiectasis (44.6%). Thirty-nine percent had normal spirometries. Compared to female patients, there were more smokers among the male patients (53.8% versus 8.5%,
CONCLUSION
The NCFB cohort in Singapore has unique characteristics with sex differences. Over half the patients had a history of haemoptysis. The BSI score is a useful predictor of mortality in our population.
Aged
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Bronchiectasis/epidemiology*
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Cohort Studies
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Female
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Fibrosis
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Humans
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Male
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Middle Aged
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Prospective Studies
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Pulmonary Medicine
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Severity of Illness Index
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Singapore/epidemiology*