Primary cutaneous lymphoma are non-Hodgkin lymphomas with no evidence of extracutaneous disease. Classified into cutaneous T-cell lymphoma and cutaneous B-cell lymphoma from the WHO-EORTC classification 2018. 10 cases per million inhabitants per year worldwide are seen, wherein 20-25% are primary cutaneous B-cell lymphomas, with PCFCL having 12% frequency. Only 17 cases of cutaneous B cell lymphoma are recorded in the Philippines from 2011 to 2023. This rare case will add to the minimal data on the disease in the Philippines.

A 70-year old, Filipino male presenting with nodules, papules and plaques on the nose, forehead, preauricular areas, and temples of the face. Histopathologically, it showed atypical lymphoid follicles which were positive for CD20 and Bcl6 and negative for Bcl2, MUM-1, Cyclin D1, CD10 and CD5. Since there was no extracutaneous involvement, the final diagnosis was Primary Cutaneous Follicle Center Cell Lymphoma. He was treated with external beam radiation therapy with complete response, and no recurrence seven months after radiation therapy.

PFCL presents as papules, plaques, or tumors with a predilection for the scalp, forehead, and posterior torso. On dermoscopy, salmon-colored area and pro-eminent serpentine vessels, some having white circles with scales and arborizing vessels. Histologically, it expresses CD20 and Bcl-6, and predominantly Bcl-2 negative, but some cases show positive cells. Imaging and work-up ruled out systemic involvement Local radiation shows a close to 100% response rate.

PCFCL is still a rare disease nationwide.

Human ; Male ; Aged: 65-79 Yrs Old