1. Research progress of 3D printing technology in congenital heart disease
Chinese Journal of Applied Clinical Pediatrics 2019;34(18):1437-1440
3D printing technology has achieved good results in the diagnosis and guidance of congenital heart disease(CHD). Computed tomography (CT) and magnetic resonance imaging (MRI) are used as data sources to establish a three-dimensional model of the heart, which has been used clinically.The use of non-invasive techniques such as three-dimensional ultrasound to obtain data sources for 3D printing models can bring about changes in the diagnosis and treatment of CHD.This paper reviews the research progress of 3D printing technology in CHD with CT, MRI and 3D ultrasound.
2.Clinical application of percutaneous pulmonary valve implantation in patients with pulmonary valve regurgitation
Dong LIANG ; Maozheng XUAN ; Jiangzhen LI ; Taibing FAN
Chinese Journal of Applied Clinical Pediatrics 2020;35(4):318-320
Percutaneous pulmonary valve implantation (PPVI) is applied relatively late in clinical practice in China as an emerging technology, but it has developed rapidly with the increasing clinical attention paid to severe pulmonary valve regurgitation in medical level in China and the clinical appearance of congenital heart disease patients with right ventricular outflow obstruction after surgery.In the past ten years, European and American countries have applied PPVI in clinical practice, which has the advantages of minimally invasive, reproducibility and good postoperative efficacy compared with traditional surgery.The clinical application of PPVI in patients with pulmonary regurgitation is summarized.
3.Early and mid-term outcomes of aortic valvuloplasty in children
Weijie LIANG ; Maozheng XUAN ; Jiangzhen LI ; Dong LIANG ; Liyun ZHAO ; Sijie ZHOU ; Shubo SONG ; Bin LI ; Manman HU ; Taibing FAN
Chinese Journal of Applied Clinical Pediatrics 2023;38(9):681-685
Objective:To analyze the short and mid-term efficacy of aortic valvuloplasty with autopericardium on children with aortic valve diseases.Methods:A total of 26 children with aortic valve diseases (stenosis or regurgitation) who underwent aortic valvuloplasty with autopericardium in Fuwai Central China Cardiovascular Hospital from September 2017 to June 2021 were retrospectively analyzed.The short-term and mid-term follow-up data were collected.The maximum aortic valve pressure gradient, subaortic regurgitation area, left ventricular end-diastolic volume (LVEDV) and left ventricular ejection fraction (LVEF) were compared before and after operation.Paired t test was used to analyze the short-term and mid-term efficacy of aortic valvuloplasty with autopericardium on children with aortic valve diseases. Results:All 26 cases were successfully operated, and there were no deaths and serious complications during the follow-up period of (22.96±6.45) months.There was a significant difference between the preoperative and postoperative maximum aortic valve pressure gradient at 1 month ( t=7.85, P<0.05), 6 months ( t=6.43, P<0.05), 1 year ( t=6.16, P<0.05) and 2 years postoperatively ( t=4.22, P<0.05) in children with aortic stenosis or that combined with mild-to-moderate closure.The follow-up data of 9 children with simple aortic stenosis showed that there was a significant difference between the preoperative (8.87±3.57) cm 2 and postoperative aortic regurgitation area at 1 month ( t=6.85, P<0.05), 6 months ( t=5.13, P<0.05), 1 year ( t=6.62, P<0.05) and 2 years postoperatively ( t=5.41, P<0.05). The LVEDV of 26 children was significantly lower at 6 months[(63.54±27.61) mL], 1 year [(53.61±20.20) mL] and 2 years postoperatively [(64.39±17.78) mL] compared with that of preoperative level[(89.42±45.89) mL]( t=3.89, 4.67, 3.58, all P<0.05). The left ventricular pressure and volume decreased, the enlarged heart was narrowed down, and the geometry of the heart was restored.The LVEF of 26 patients also from (61.65±9.67)% before surgery increased to (67.88±4.69)% 6 months after surgery( t=3.68, P<0.05), and increased to (68.62±4.46)% 1 year after surgery( t=4.01, P<0.05), and increased to (67.55±3.09)% 2 years after operation( t=3.01, P<0.05), and the heart function was improved. Conclusions:Aortic valvuloplasty with autopericardium presents an effective short and mid-term efficacy on children with aortic valve diseases, which prevents or delays the aortic valve replacement.