Objective To study the influence of different time of lavipeditum with traditional Chinese medicine on recovery of gastrointestinal function right after cesarean section, to find the best lavipeditum time and improve the therapeutic effect of lavipeditum with traditional Chinese medicine. Methods 388 cases parturents after cesarean section were selected and were randomly divided into the observation group(200 cases)and the control group(188 cases)according to their bed number. The observation group began lavipeditum with Chinese medicine 6 hours after operation, and was scheduled 7:00-8:00 in the morning, 21:00-22:00 in the evening, lasted 20 minutes every time for consecutive 3 to 5 days. the control group started lavipeditum with Chinese medicine one day after operation, and continued lavipeditum any time they wanted. lasted 20 minutes every time for consecutive 3 to 5 days. Recovery of intestinal function were com-pared between the two groups. Results Postoperative recovery time of bowel sounds, anal exhaust time for the first time, the first defecation time, appetite and sleep quality three days after operation in the observation group were beuer compared with the control group. Conclusions Timing of lavipeditum with Chinese medicine is more effective for recovery of gastrointestinal function after cesarean section, it embodies the importance of time medicine and reach best aims.

Objective: To investigate the apoptosis-inducing effect of arsenic trioxide (As2O3) on gastric carcinoma cell line AGS in vitro and to assess the influence of As2O3 on the expression of signal transducers and activators of transcription 3 (STAT3) and vascular endothelial growth factor (VEGF). Methods: AGS cells were treated with different concentrations of As2O3 (1, 5, and 10 ?mol/L) for 24,48, and 72 h. The cell proliferation was detected by MTT assay, cell apoptosis and cell cycle distribution were measured by flow cytometry and TUNEL, and the expression of STAT3 and VEGF was investigated by ELISA, immunohistochemistry and real-time PCR. Results: (1) As2O3 inhibited AGS cell proliferation in a time- and dose-dependent manner; (2) FCM results showed a typical sub-diploid peak before G0/ G1 phase and cell cycle analysis showed G2/M phase arrest; (3) TUNEL analysis revealed the DNA fragmentation; (4) During the As2O3-induced apoptosis of AGS cells, the expression of STAT3 and VEGF was down-regulated, especially when As2O3 was at 10 mol/L. Conclusion: As2O3 can inhibit the proliferation of AGS cells and induce AGS cell apoptosis, which might be related with cell cycle block and down-regulation of STAT3 and VEGF expression.