Differentiation of syndromes by zang-fu viscera is the core of syndrome differentiation of Traditional Chinese Medicine.The logical contradiction which is very difficult to be solved due to the same-position relationship,cause-result relationship and subordinate relationship between the various zang-fu viscera syndromes,however,often lead to a relatively serious side effect on the system of syndrome differentiation in clinic.The aim of this paper is to reveal the logical contradictory relationship between the zangfu viscera syndromes,to invite the scientific field to pay attention on the problem and solve it.

There is a very serious logical contradiction among the basic conceptions in Chinese medicine such as syndrome,symptoms and signs,pathogens and pathogenesis.And the situation get worse after the new conceptions melt in,which include key pattern elements,syndrome pattern,pattern,pattern of syndrome differentiation and so on.It is urgent and necessary for signifi cant and basic Chinese medicine research that we should unify,normalize and purify the basic conceptions in Chinese medicine,by merging,accepting and rejecting of the conceptions or the terms concerned on the basis of the defi nition of the connotation anew.

Syndrome attribute determined by signs and symptoms of an animal model through intervening in the clini-cal and animal syndrome differentiation standards is not standardized, objective or rigorous. The signs and symptoms of people are difficult to be expressed fully and accurately in the animal body correspondingly. The signs and symptoms of animals are mostly without any syndrome information. There are no difference of signs and symptoms among differ-ent modeling methods. Hence, it is difficult to determine the syndrome-attribution of an animal model based on signs and symptoms. There are two problems in drug reduction to determine syndrome-attribution of animal models. Firstly, for drug reduction, only one group is used in the animal subject. There are no other two groups or multi-groups of drugs compared with each other to confirm the syndrome-attribution of animal models. Lots of research results indicat-ed that multiple drugs with different functions can change the state and the objective index of the same animal subject. Secondly, employing the control principle, adjusting and improving the best drug for the animal subject were used to determine the syndrome-attribute. However, these studies cannot be operated, because the preliminary studies, such as the essence of syndrome, have not provided generally recognized effect indexes and index groups.

Intervening animals by pathogen of traditional Chinese medicine (TCM) to establish animal model is the most common and easiest method to determine syndrome attribute of an animal model. However, the underlying prob-lem of this modeling method is that the concept of wind, cold and dampness in the nature are confused with the syn-drome of wind-cold-dampness summarized by abnormal appearance of clinical patients. The typical animal model establishment are through the methods of wind blowing, low temperature freezing, cold water immersion, environmen-tal humidity increasing. Modern medical modeling methods, such as chemicals, organ resections, are also used in the establishment of animal models. Then, the syndrome-attribution of modeling animal is evaluated by physicochemical indexes of modern medicine which is one of modeling methods that have been used by academia in early times. But animal model established by this method is a kind of disease model which is lack of sufficient theoretical and clini-cal evidences. Therefore, the syndrome-attribution should be reappraised among this kind of animal models.

Studies showed that animal model of the so-called simple syndrome currently have corresponding modern medical disease without exception. Even such animal model is called simple syndrome model, its properties is a cer-tain modern medicine disease. There is no specific corresponding relationship between the syndrome-attribution and the syndrome. The signs and symptoms differentiation and abnormal physical and chemical detection indices after pathogen-modeling of traditional Chinese medicine (TCM) cannot be determined since there are no specific corre-sponding relationships. The study on disease-syndrome combination model contains both modern medical modeling method and TCM modeling method. This type of modeling method has its own existing shortcomings. Meanwhile, two modeling methods used in the model establishment have uncertain relationship. The disease-syndrome combination model is usually not established in the comparison among different syndromes of one disease. Therefore, it has no ex-clusive attribute. There are many problems existed in the TCM modeling method, disease-syndrome combination modeling method, and syndrome-attribute evaluation methods. The basic reasons are the wide difference between symptoms and signs for diagnosis in modern medicine disease. There are a few symptoms and signs for diagnosis in modern medicine. But there are much more symptoms and signs for syndrome differentiation of the same disease. Many symptoms for syndrome differentiation are unknown for its source of origin existed in a virtual state. It caused that many virtual syndromes abstracted by virtual symptoms, and was reflected by the relevant standards. It leads to devastating consequences for the development of animal modeling method.

The canonical or official functions of formulae and traditional Chinese patent medicines and simple preparations are generally existing issues in terms of non-integrated presentation(short of the functions aiming at pathogeny and pathogenesis),confusion of logical relation and inconsistent indication etc.It causes a biggish negative influence on traditional Chinese medicine.This article has analyzed and explained these questions using a lot of illustrations,and given concrete ways of settling these issues.

Take the common diseases of TCM as the objects such as cough,retention of phlegm and morbid fluid,vomiting,diarrhea,diabetes,edema,stranguria,abdominal mass,jaundice,and consumption,the inherits and the differences in zang-fu syndromes of diseases between ancient time and now were inspected.As a result,a big difference has been appeared in zang-fu syndromes in distribution of same disease between ancient time and now.It mainly displays in: The quantity of zang-fu localizations of disease attribute is different;it has diversity on specific zang-fu organs in syndrome differentiation of disease;the main connected zang-fu organs are different;natures of zang-fu syndromes are different.It has the vital significance to profoundly understand the essence of treatment based on syndrome differentiation through out promulgating the tremendous changes of zang-fu syndrome differentiation of diseases between ancient and modern times.

Objective:To approach the potential rules ofsyndrome differentiation and medication for diabetes by ancient medical scholars.Methods:By DBMS(Data Base Management System) ofPuji Fang, the information about diabetes and its correlated disease was collected, such as kinds ofthe drugs, application times ofdrugs and the number ofprescription.The qualitative analysis and quantitive analysis were used to ascertain the optimal and common used drugs and pairs ofdrugs for diabetes, and to deduce the potential indication ofdiabetes in ancient times.Results:The most optimal drugs used for diabetes in ancient times were DwarfLilyturfTuber, trichosanthis, Ginseng and Indian Bread.The common used pairs ofdrugs were DwarfLilyturfTuber and trichosanthis, DwarfLilyturfTuber and Ginseng, trichosanthis and Golden Thread, Ginseng and Indian Bread.So we can deduce that the potential indications ofdiabetes were impairment ofbody fluid by dry and heat, and deficiency ofboth qi and yin.Conclusion:By integrated logic analysis and statistical analysis, we can reveal the ancient treatment rule ofthe disease and it provided reference for clinic today.

To compare herbalogy literature through the ages, ancient prescription literature, modern national pharmacopoeia and modern Chinese materia medica, we can confirm that the core of the traditional functions about atractylodes macrocephala have been recorded in modern national pharmacopoeia and Chinese materia medica. But atractylodes macrocephala's effects in treating anemofrigid-damp arthralgia, vomit, abdominal crymodynia, hypochondnrium or abdominal mass, chills and fever, all anemo-illness, dead muscle, gastric heat, spasm, jaundice, violent pathogenic wind, headache, five kinds of strain and seven impairments, therm-disease, epidemic pathogenic factors from mountains, knob and boss, agerasia and so on, were not included nowadays. By analysing the syndrome of the compatibility in ancient prescriptions including atractylodes macrocephala, some functions can be extracted, such as eliminating fever, calming down wind and stopping spasm, stopping cough, stopping wheez, calming the nerves, stopping bleeding, alleviating pain, promoting the production of body fluid. Whether atractylodes macrocephala has those functions need to be confirmed through empirical study and clinical research.

There was severe logical contradiction among the basic concepts in Chinese medicine such as syndrome, symptoms and signs, etiopathogenisis and pathogenesis .In this paper, from the comparative reseaech of the different versions of Basic Theory of Traditional Chinese Medicine (TCM) used in higher colleges and universities of TCM in recent 50 years,higher Colleges of Chinese medicine materials, it cleared up the evolution of the basic connotation of syndrome, symptoms and signs, pathogens and pathogenesis, and revealed fundamental reason for the occurance of logical contradiction.